Coeliac disease - A future for peptide therapy?

Lancet

Volumn 356, Issue 9226, 2000, Pages 270-271

  Mowat, A M ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLIADIN; HLA DQ ANTIGEN; PEPTIDE;

AMINO ACID SEQUENCE; ANTIGEN RECOGNITION; CELIAC DISEASE; GLUTEN FREE DIET; HUMAN; IMMUNOLOGICAL TOLERANCE; NOTE; PATIENT COMPLIANCE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0034702570     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)02499-5     Document Type: Note

References (19)

1. H Arentz‐Hansen R Körner Ø Molberg The intestinal T cell response to alpha‐gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase J Exp Med 191 2000 603 612
2. RP Anderson P Degano AJ Godkin DP Jewell AVS Hill In vivo antigen challenge in celiac disease identifies a single transglutaminasemodified peptide as the dominant A‐gliadin T‐cell epitope Nat Med 6 2000 337 342
3. TT MacDonald M Bajaj‐Elliott SLF Pender T cells orchestrate intestinal mucosal shape and integrity Immunol Today 20 1999 505 510
4. EM Nilsen KE Lundin P Krajci H Scott LM Sollid P Brandtzaeg Gluten specific, HLA‐DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma Gut 37 1995 766 776
5. LM Sollid E Thorsby HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis Gastroenterology 105 1993 910 922
6. DR Madden The three dimensional structure of peptide MHC complexes Ann Rev Immunol 13 1995 587 622
7. G Mantzaris DP Jewell In vivo toxicity of a synthetic dodecapeptide from A gliadin in patients with coeliac disease Scand J Gastroenterol 26 1991 392 398
8. *0201) heterodimer Human Immunol 39 1994 243 252
9. R Sturgess P Day HJ Ellis Wheat peptide challenge in coeliac disease Lancet 343 1994 758 761
10. RG Shidrawi P Day R Przemioslo HJ Ellis JM Nelufer PJ Ciclitira In vitro toxicity of gluten peptides in coeliac disease assessed by organ culture Scand J Gastroenterol 30 1995 758 763
11. G de Ritis S Auricchio HW Jones EJ Lew JE Bernardin DD Kasarda In vitro (organ culture) studies of the toxicity of specific A‐gliadin peptides in celiac disease Gastroenterology 94 1988 41 49
12. Y van de Wal YM Kooy PA Van Veelen Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin Proc Natl Acad Sci 95 1998 10050 10054
13. M ten Dam Y Van de Wal ML Mearin Anti‐alpha‐gliadin antibodies (AGA) in the serum of coeliac children and controls recognize an identical collection of linear epitopes of alpha‐gliadin Clin Exp Immunol 114 1998 189 195
14. Ø Molberg SN McAdam R Körner Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut‐derived peptides in celiac disease Nat Med 4 1998 713 717
15. Y van de Wal Y Kooy P Van Veelen W Vader F Koning S Pena Coeliac disease: it takes three to tango! Gut 46 2000 734 737
16. AMcI Mowat Dietary modifications: food dependent autoimmunity in coeliac disease Gut 43 1998 599 600
17. *0201) molecule Immunogenetics 44 1996 246 253
18. AMcI Mowat HL Weiner Oral tolerance: basic mechanisms and clinical implications Ogra PL Mestecky J Lamm ME Strober W McGhee JR Bienenstock J Mucosal Immunol 2nd edn. 1999 Academic Press San Diego 587 617
19. C Lock D Smilek A Gautam M Vaysburd S Dwivedy H McDevitt Competitive inhibition of antigen presentation in animal models of autoimmune disease Semin Immunol 3 1991 247 255