Interactions between 18-methoxycoronaridine (18-MC) and cocaine: Dissociation of behavioural and neurochemical sensitization

Brain Research

Volumn 871, Issue 2, 2000, Pages 245-258

  Szumlinski, Karen K ^a   McCafferty, Caterina A ^b   Maisonneuve, Isabelle M ^a   Glick, Stanley D ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

18 Methoxycoronaridine (18 MC); Cocaine; Dopamine; Drug addiction; Locomotor activity; Sensitization

Indexed keywords

18 METHOXYCORONARIDINE; ALKALOID; BENZOYLECGONINE; COCAINE; NORCOCAINE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG DEPENDENCE; FEMALE; LONG TERM CARE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SENSITIZATION; STEREOTYPY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; FEMALE; IBOGAINE; MICRODIALYSIS; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; STEREOTYPED BEHAVIOR;

EID: 0034698424     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02424-0     Document Type: Article

References (55)

1. A.V. Azaryan, B.J. Clock, J.G. Rosenberger, B.M. Cox, Transient upregulation of μ, opioid receptor mRNA levels in nucleus accumbens during chronic cocaine administration, Can. J. Physiol. Pharmacol. 76 (1998) 278-283.
2. H.N. Bhargava, S. Kumar, Sensitization to the locomotor stimulant effect of cocaine modifies the binding of [3H]MK-801 to brain regions and spinal cord of the mouse, Gen. Pharmacol. 32 (1999) 359-363.
3. K.C. Berridge, T.E. Robinson, What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?, Brain Res. Rev. 28 (1998) 309-369.
4. J.R. Blackburn, K.K. Szumlinski, Ibogaine effects on sweet preference and amphetamine-induced locomotion: Implications for drug addiction, Behav. Brain Res. 89 (1997) 99-106.
5. C. Cadoni, G. Di Chiara, Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine, Eur. J. Pharmacol. 387 (2000) R23-25.
6. C. Cadoni, G. Di Chiara, Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine, Neuroscience 90 (1999) 447-455.
7. C. Cadoni, M. Solinas, G. Di Chiara, Psychostimulant sensitization: differential changes in accumbal shell and core dopamine, Eur. J. Pharmacol. 388 (2000) 69-76.
8. S. Cohen, Cocaine, J. Am. Med. Assoc 231 (1972) 74-75.
9. V. Deroche, M. Le Moal, P.V. Piazza, Cocaine self-administration increases the incentive motivational properties of the drugs in rats, Eur. J. Neurosci. 11 (1999) 2731-2736.
10. T.J. De Vries, A.N.M. Schoffelmeer, R. Binnekade, A.H. Mulder, L.J.M.J. Vanderschuren, Drug-induced reinstatement of heroin- and cocaine-seeking behaviour following long-term extinction is associated with expression of behavioural sensitization, Eur. J. Neurosci. 10 (1998) 3565-3571.
11. G. Di Chiara, Drug addiction as dopamine-dependent associative learning disorder, Eur. J. Pharmacol. 375 (1999) 13-30.
12. F.J. Dunne, Substance misuse in the young, Br. J. Hosp. Med. 50 (1993) 643-649.
13. V.S. Estevez, B.T. Ho, L.F. Englert, Inhibition of the metabolism of cocaine by SKF-525A, Res. Commun. Chem. Pathol. Pharmacol. 17 (1977) 179-182.
14. J.L. Falk, F. Ma, C.E. Lau, Chronic oral cocaine self-administration pharmacokinetics and effects on spontaneous and discriminative motor functions, J. Pharmacol. Exp. Ther. 257 (1991) 57-465.
15. H.C. Fibiger, A.G. Phillips, Reward, motivation, cognition: Psychobiology of mesotelencephalic dopamine systems, in: V.B. Mountcastle, F.E. Bloom, S.R. Geiger (Eds.), Handbook of physiology: the nervous system, Vol. 4, American Physiological Society, Bethesda, MD, 1986, pp. 647-675.
16. G. Frenken, From the roots up: Ibogaine and addict self-help, in: K.R. Alper, S.D. Glick (Eds.) The Alkaloids. Ibogaine: Proceedings of an Interdisciplinary Conference. Academic Press, New York, 2000, in press.
17. F.H. Gawin, M.E. Khalsa-Denison, Is craving mood-driven or self-propelled? Sensitization and "street" stimulant addiction, NIDA Res. Monogr. 163 (1999) 224-250.
18. S.D. Glick, M.E. Kuehne, I.M. Maisonneuve, U.K. Bandarage, H.H. Molinari, 18-methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats, Brain Res. 719 (1996) 29-35.
19. S.D. Glick, I.M. Maisonneuve, Mechanisms of anti-addictive actions of ibogaine, Ann. N.Y. Acad. Sci. 844 (1998) 214-226.
20. S.D. Glick, I.M. Maisonneuve, L.B. Hough, M.E. Kuehne, U.K. Bandarage, (±)-18-Methoxycoronaridine: A novel iboga alkaloid congener having potential anti-addictive efficacy, CNS Drug Rev. 5 (1999) 27-42.
21. S.D. Glick, I.M. Maisonneuve, K.K. Szumlinski, 18-Methoxycoronaridine (18-MC) and ibogaine: comparison of anti-addictive efficacy, toxicity and mechanisms of action. Ann. N.Y. Acad. Sci. (1999), in press.
22. C.A. Heidbreder, J. Feldon, Amphetamine-induced neurochemical and locomotor responses are expressed differentially across the anteroposterior axis of the core and shell subterritories of the nucleus accumbens, Synapse 29 (1998) 310-322.
23. A.L. Jongen-Relo, H.J. Groenewegen, P. Voorn, Evidence for a multi-compartmental histochemical organization of the nucleus accumbens in the rat, J. Comp. Neurol. 337 (1993) 267-276.
24. P.W. Kalivas, P. Duffy, L.A. DuMars, C. Skinner, Behavioral and neurochemical effects of acute and daily cocaine administration in rats, J. Pharmacol. Exp. Ther. 245 (1988) 485-492.
25. P.W. Kalivas, R.C. Pierce, J. Cornish, B.A. Sorg, A role for sensitization in craving and relapse in cocaine addiction, J. Psychopharmacol. 12 (1998) 49-53.
26. P.W. Kalivas, J. Stewart, Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity, Brain Res. Rev. 16 (1991) 223-244.
27. G.F. Koob, Drugs of abuse: Anatomy, pharmacology and function of reward pathways, Trends Pharmacol. Sci. 13 (1992) 177-184.
28. J.C. Kramer, Introduction to amphetamine abuse, in: E.H. Ellinwood, S. Cohen (Eds.), Current Concepts in Amphetamine Abuse, NIMH, Rockville, MD, 1970, pp. 177-184.
29. I.M. Maisonneuve, S.D. Glick, Interactions between ibogaine and cocaine in rats: in vivo microdialysis and motor behavior, Eur. J. Pharmacol. 212 (1992) 263-266.
30. I.M. Maisonneuve, R.W. Keller Jr., S.D. Glick, Interactions of ibogaine and D-amphetamine: in vivo microdialysis and motor behaviour in rats, Brain Res. 579 (1992) 87-92.
31. I.M. Maisonneuve, K.E. Visker, G.L. Mann, U.K. Bandarage, M.E. Kuehne, S.D. Glick, Time-dependent interactions between iboga agents and cocaine, Eur. J. Pharmacol. 336 (1997) 123-126.
32. 3H]cocaine in acutely and chronically treated rats, J. Pharmacol. Exp. Ther. 196 (1976) 556-569.
33. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, Orlando, FL, 1984.
34. S.M. Pearl, D.W. Johnson, S.D. Click, Prior morphine exposure enhances ibogaine antagonism of morphine-induced locomotor stimulation, Psychopharmacology 121 (1995)470-475.
35. A.C. Phillips, P. Di Ciano, Behavioural sensitization is induced by intravenous self-administration of cocaine by rats, Psychopharmacology 124 (1996) 279-281.
36. M.E.A. Reith, M. Benuck, A. Lajtha, Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice, J. Pharmacol. Exp. Ther. 243 (1987) 281-287.
37. T.E. Robinson, J.B. Becker, Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis, Brain Res. Rev. 11 (1986) 157-198.
38. T.E. Robinson, K.C. Berridge, The neural basis of drug craving: an incentive-sensitization theory of drug addiction, Brain Res. Rev. 18 (1993) 247-291.
39. S.G. Sheppard, A preliminary investigation of ibogaine: case reports and recommendations for further study, J. Subst. Abuse Treat. 11 (1994) 379-385.
40. J. Stewart, Conditioned stimulus control of the expression of sensitization of the behavioral activating effects of opiate and stimulant drugs, in: I. Gormezano, E.A. Wasserman (Eds.), Learning and Memory: Behavioral and Biological Substrates, Lawrence Erlbaum Publishers, Hillsdale, NJ, 1982, pp. 129-151.
41. J. Stewart, A. Badiani, Tolerance and sensitization to the behavioral effects of drugs, Behav. Pharmacol. 4 (1993) 289-312.
42. K.K. Szumlinski, M.Y. Balogun, I.M. Maisonneuve, S.D. Glick, Interactions between iboga agents and methamphetamine sensitization: studies of locomotion and stereotypy in rats, Psychopharmacology (2000), in press.
43. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, Ibogaine enhances the expression of locomotor sensitization in rats chronically treated with cocaine, Pharmacol. Biochem. Behav. 63 (1999) 457-464.
44. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, Pretreatment with the putative anti-addictive drug, ibogaine, increases the potency of cocaine to elicit locomotor responding: a study with acute and chronic cocaine-treated rats, Psychopharmacology 145 (1999) 227-233.
45. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, Iboga agents enhance the expression of cocaine-induced stereotypy in acute and chronic cocaine-treated rats, Behav. Pharmacol. 10 (1999) S92.
46. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, 18-Methoxycoronaridine (18-MC) differentially alters the sensitized behavioural and dopaminergic responses to repeated cocaine and morphine administration: Implications for sensitization in the mediation of drug addiction, Ann. N.Y. Acad. Sci. (2000), in press.
47. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, The potential anti-addictive agent, 18-methoxycoronaridine (18-MC) blocks the sensitized dopamine and locomotor responses produced by repeated morphine treatment, Brain Res. 864 (2000) 13-23.
48. J. Turchan, B. Przewlocka, W. Lason, R. Przewlocki, Effects of repeated psychomotorstimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain, Neuroscience 85 (1998) 1051-1059.
49. J. Turchan, B. Przewlocka, G. Toth, W. Lason, A. Borsodi, R. Przewlocki, The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat, Neuroscience 91 (1999) 971-977.
50. E.M. Unterwald, J.M. Rubenfeld, M.J. Kreek, Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors, Neuroreport 15 (1994) 1613-1616.
51. R.A. Wise, M.A. Bozarth, A psychomotor stimulant theory of addiction, Psychol. Rev. 94 (1987) 469-492.
52. V. Yuferov, Y. Zhou, R. Spangler, C.E. Maggos, A. Ho, M.J. Kreek, Acute "binge" cocaine increases mu-opioid receptor mRNA levels in areas of the rat mesolimbic mesocortical dopamine system, Brain Res. Bull. 48 (1999) 109-112.
53. D.S. Zahm, Functional-anatomical implications of the nucleus accumbens core and shell territories, Ann. N.Y. Acad. Sci. 877 (1999) 113-128.
54. D.S. Zahm, L. Heimer, Specificity in the efferent projections of the nucleus accumbens in the rat: Comparison of the rostral pole projection patterns with those of the core and shell, J. Comp. Neurol. 327 (1993) 220-232.
55. K.K. Szumlinski, I.M. Maisonneuve, S.D. Glick, Differential effects of ibogaine on behavioural and dopamine sensitization, Eur. J. Pharmacol. (2000), in press.