메뉴 건너뛰기




Volumn 5, Issue 1, 1999, Pages 27-42

(±)- 18-methoxycoronaridine: A novel Iboga alkaloid congener having potential anti-addictive efficacy

Author keywords

Addiction; Dependence; Dopamine; Drug self administration; Ethanol; In vivo microdialysis; Nicotine; Nicotinic receptors; NMDA receptors; Opioid receptors; Opioids; Serotonin; Sigma2 receptors; Stimulants

Indexed keywords

18 METHOXYCORONARIDINE; ALCOHOL; CENTRAL STIMULANT AGENT; DOPAMINE; IBOGAINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINE; NICOTINIC RECEPTOR; OPIATE; OPIATE RECEPTOR; SEROTONIN; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

EID: 0032885961     PISSN: 1080563X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3458.1999.tb00084.x     Document Type: Review
Times cited : (40)

References (42)
  • 1
    • 0032500737 scopus 로고    scopus 로고
    • Transition from moderate to excessive drug intake: Change in hedonic set point
    • Ahmed SH, Koob GF. Transition from moderate to excessive drug intake: Change in hedonic set point. Science 1998;282:298-300.
    • (1998) Science , vol.282 , pp. 298-300
    • Ahmed, S.H.1    Koob, G.F.2
  • 2
    • 0031024617 scopus 로고    scopus 로고
    • Ibogaine: A potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors
    • Badio B, Padgett WL, Daly JW. Ibogaine: A potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors. Mol Pharmacol 1997;51:1-5.
    • (1997) Mol Pharmacol , vol.51 , pp. 1-5
    • Badio, B.1    Padgett, W.L.2    Daly, J.W.3
  • 5
    • 0027329007 scopus 로고
    • Inhibitory effects of ibogaine on cocaine self-administration in rats
    • Cappendijk SLT, Dzoljic MR. Inhibitory effects of ibogaine on cocaine self-administration in rats. Eur J Pharmacol 1993;241:261-265.
    • (1993) Eur J Pharmacol , vol.241 , pp. 261-265
    • Cappendijk, S.L.T.1    Dzoljic, M.R.2
  • 8
    • 0023766225 scopus 로고
    • Effect of ibogaine on naloxone precipitated withdrawal syndrome in chronic morphine dependent rats
    • Dzoijic ED, Kaplan CD, Dzoljic MR. Effect of ibogaine on naloxone precipitated withdrawal syndrome in chronic morphine dependent rats. Arch Int Pharmacodyn 1988;294:64-70.
    • (1988) Arch Int Pharmacodyn , vol.294 , pp. 64-70
    • Dzoijic, E.D.1    Kaplan, C.D.2    Dzoljic, M.R.3
  • 9
    • 0029932986 scopus 로고    scopus 로고
    • 18- Methoxycoronaridine, a non-toxic iboga alkaloid congener: Effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats
    • Glick SD, Kuehne ME, Maisonneuve IM, Bandarage UK, Molinari HH. 18- Methoxycoronaridine, a non-toxic iboga alkaloid congener: Effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. Brain Res 1996;719:29-35.
    • (1996) Brain Res , vol.719 , pp. 29-35
    • Glick, S.D.1    Kuehne, M.E.2    Maisonneuve, I.M.3    Bandarage, U.K.4    Molinari, H.H.5
  • 10
    • 0027977892 scopus 로고
    • Effects of iboga alkaloids on morphine and cocaine self-administration in rats: Relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum
    • Glick SD, Kuehne ME, Raucci J, et al. Effects of iboga alkaloids on morphine and cocaine self-administration in rats: Relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. Brain Res 1994;657:14-22.
    • (1994) Brain Res , vol.657 , pp. 14-22
    • Glick, S.D.1    Kuehne, M.E.2    Raucci, J.3
  • 11
    • 0029001901 scopus 로고
    • Kappa opioid inhibition of morphine and cocaine self-administration in rats
    • Glick SD, Maisonneuve IM, Raucci J, Archer S. Kappa opioid inhibition of morphine and cocaine self-administration in rats. Brain Res 1995;681:147-152.
    • (1995) Brain Res , vol.681 , pp. 147-152
    • Glick, S.D.1    Maisonneuve, I.M.2    Raucci, J.3    Archer, S.4
  • 14
    • 0026554710 scopus 로고
    • Effects of ibogaine on acute signs of morphine withdrawal in rats: Independence from tremor
    • Glick SD, Rossman K, Rao NC, Maisonneuve IM, Carlson JN. Effects of ibogaine on acute signs of morphine withdrawal in rats: Independence from tremor. Neuropharmacology 1992;31:497-500.
    • (1992) Neuropharmacology , vol.31 , pp. 497-500
    • Glick, S.D.1    Rossman, K.2    Rao, N.C.3    Maisonneuve, I.M.4    Carlson, J.N.5
  • 15
    • 0026021819 scopus 로고
    • Effects and after-effects of ibogaine on morphine self-administration in rats
    • Glick SD, Rossman K, Steindorf S, Carlson JN. Effects and after-effects of ibogaine on morphine self-administration in rats. Eur J Pharmacol 1991;195:341-345.
    • (1991) Eur J Pharmacol , vol.195 , pp. 341-345
    • Glick, S.D.1    Rossman, K.2    Steindorf, S.3    Carlson, J.N.4
  • 16
    • 0342313495 scopus 로고    scopus 로고
    • Tissue distribution of ibogaine after intraperitoneal and subcutaneous administration
    • Hough LB, Pearl SM, Glick SD. Tissue distribution of ibogaine after intraperitoneal and subcutaneous administration. Life Sci 1996;58:PL119-122.
    • (1996) Life Sci , vol.58
    • Hough, L.B.1    Pearl, S.M.2    Glick, S.D.3
  • 17
    • 0024550767 scopus 로고
    • Role of opioid antagonists in treating intravenous cocaine abuse
    • Kosten TR, Kleber HD, Morgan C. Role of opioid antagonists in treating intravenous cocaine abuse. Life Sci 1989;44:887-892.
    • (1989) Life Sci , vol.44 , pp. 887-892
    • Kosten, T.R.1    Kleber, H.D.2    Morgan, C.3
  • 19
    • 0013848559 scopus 로고
    • A uniform numbering system for indole alkaloids
    • Le Men J, Taylor WI. A uniform numbering system for indole alkaloids. Experientia 1965;21:508-510.
    • (1965) Experientia , vol.21 , pp. 508-510
    • Le Men, J.1    Taylor, W.I.2
  • 21
    • 0026544018 scopus 로고
    • Interactions between ibogaine and cocaine in rats: In vivo microdialysis and motor behavior
    • Maisonneuve IM, Glick SD. Interactions between ibogaine and cocaine in rats: In vivo microdialysis and motor behavior. Eur J Pharmacol 1992;212:263-266.
    • (1992) Eur J Pharmacol , vol.212 , pp. 263-266
    • Maisonneuve, I.M.1    Glick, S.D.2
  • 22
    • 0025853499 scopus 로고
    • Interactions between ibogaine, a potential anti-addictive agent, and morphine: In vivo microdialysis study
    • Maisonneuve IM, Keller RW, Glick SD. Interactions between ibogaine, a potential anti-addictive agent, and morphine: In vivo microdialysis study. Eur J Pharmacol 1991;199:35-42.
    • (1991) Eur J Pharmacol , vol.199 , pp. 35-42
    • Maisonneuve, I.M.1    Keller, R.W.2    Glick, S.D.3
  • 24
    • 0026563313 scopus 로고
    • Acute and prolonged effects of ibogaine on brain dopamine metabolism and morphine-induced locomotor activity in rats
    • Maisonneuve IM, Rossman KL, Keller RW, Glick SD. Acute and prolonged effects of ibogaine on brain dopamine metabolism and morphine-induced locomotor activity in rats. Brain Res 1992;575:69-73.
    • (1992) Brain Res , vol.575 , pp. 69-73
    • Maisonneuve, I.M.1    Rossman, K.L.2    Keller, R.W.3    Glick, S.D.4
  • 26
    • 0029001030 scopus 로고
    • Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex
    • Mash DC, Staley JK, Pablo JP, Holohean AM, Hackman JC, Davidoff RA. Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex. Neurosci Lett 1995;192:53-56.
    • (1995) Neurosci Lett , vol.192 , pp. 53-56
    • Mash, D.C.1    Staley, J.K.2    Pablo, J.P.3    Holohean, A.M.4    Hackman, J.C.5    Davidoff, R.A.6
  • 28
    • 0027419954 scopus 로고
    • Ibogaine induces glial activation in parasagittal zones of the cerebellum
    • O'Hearn E, Long DB, Molliver ME. Ibogaine induces glial activation in parasagittal zones of the cerebellum. Neuroreport 1993;4:299-302.
    • (1993) Neuroreport , vol.4 , pp. 299-302
    • O'Hearn, E.1    Long, D.B.2    Molliver, M.E.3
  • 29
    • 0027171217 scopus 로고
    • Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after ibogaine or harmaline
    • O'Hearn E, Molliver ME. Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after ibogaine or harmaline. Neuroscience 1993;55:303-310.
    • (1993) Neuroscience , vol.55 , pp. 303-310
    • O'Hearn, E.1    Molliver, M.E.2
  • 30
    • 0028937127 scopus 로고
    • Radioligand binding study of noribogaine, a likely metabolite of ibogaine
    • Pearl SM, Herrick-Davis K, Teitler M, Glick SD. Radioligand binding study of noribogaine, a likely metabolite of ibogaine. Brain Res 1995;675:342-344.
    • (1995) Brain Res , vol.675 , pp. 342-344
    • Pearl, S.M.1    Herrick-Davis, K.2    Teitler, M.3    Glick, S.D.4
  • 31
    • 0030796645 scopus 로고    scopus 로고
    • Sex differences in ibogaine antagonism of morphine-induced locomotor acitvity and in ibogaine brain levels and metabolism
    • Pearl SM, Hough LB, Boyd DL, Glick SD. Sex differences in ibogaine antagonism of morphine-induced locomotor acitvity and in ibogaine brain levels and metabolism. Pharmacol Biochem Behav 1997;57:809-815.
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 809-815
    • Pearl, S.M.1    Hough, L.B.2    Boyd, D.L.3    Glick, S.D.4
  • 32
    • 0029562346 scopus 로고
    • NMDA antagonist properties of the putative antiaddictive drug, ibogaine
    • Popik P, Layer RT, Fossom LH, et al. NMDA antagonist properties of the putative antiaddictive drug, ibogaine. J Pharmacol Exp Ther 1995;275:753-760.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 753-760
    • Popik, P.1    Layer, R.T.2    Fossom, L.H.3
  • 34
    • 0028244851 scopus 로고
    • Abbreviated ibogaine congeners. Synthesis and reactions of tropan-3-yl-2 and -3-indoles. Investigation of an unusual isomerization of 2-substituted indoles using computational and spectroscopic techniques
    • Repke DB, Artis DR, Nelson JT, Wong EHF. Abbreviated ibogaine congeners. Synthesis and reactions of tropan-3-yl-2 and -3-indoles. Investigation of an unusual isomerization of 2-substituted indoles using computational and spectroscopic techniques. J Org Chem 1994;59:2164-2171.
    • (1994) J Org Chem , vol.59 , pp. 2164-2171
    • Repke, D.B.1    Artis, D.R.2    Nelson, J.T.3    Wong, E.H.F.4
  • 35
    • 0029142626 scopus 로고
    • Attenuation of alcohol intake by ibogaine in three strains of alcohol-preferring rats
    • Rezvani AH, Overstreet DH, Lee YW. Attenuation of alcohol intake by ibogaine in three strains of alcohol-preferring rats. Pharmacol Biochem Behav 1995;52:615-620.
    • (1995) Pharmacol Biochem Behav , vol.52 , pp. 615-620
    • Rezvani, A.H.1    Overstreet, D.H.2    Lee, Y.W.3
  • 36
    • 0030830104 scopus 로고    scopus 로고
    • Attenuation of alcohol consumption by a novel non-toxic ibogaine analog (18-methoxycoronaridine) in alcohol preferring rats
    • Rezvani AH, Overstreet DH, Yang Y, et al. Attenuation of alcohol consumption by a novel non-toxic ibogaine analog (18-methoxycoronaridine) in alcohol preferring rats. Pharmacol Biochem Behav 1997;58:615-619.
    • (1997) Pharmacol Biochem Behav , vol.58 , pp. 615-619
    • Rezvani, A.H.1    Overstreet, D.H.2    Yang, Y.3
  • 37
    • 0032507673 scopus 로고    scopus 로고
    • Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats
    • Rho B, Glick SD. Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats. Neuroreport 1998;9:1283-1285.
    • (1998) Neuroreport , vol.9 , pp. 1283-1285
    • Rho, B.1    Glick, S.D.2
  • 38
    • 0030593916 scopus 로고    scopus 로고
    • Ibogaine selectively inhibits nicotinic receptor-mediated catecholamine release
    • Schneider AS, Nagel JE, Mah SJ. Ibogaine selectively inhibits nicotinic receptor-mediated catecholamine release. Eur J Pharmacol 1996;317:R1-R2.
    • (1996) Eur J Pharmacol , vol.317
    • Schneider, A.S.1    Nagel, J.E.2    Mah, S.J.3
  • 39
    • 0029844299 scopus 로고    scopus 로고
    • Pharmacological screen for activities of 12-hydroxyibogamine: A primary metabolite of the indole alkaloid ibogaine
    • Staley JK, Ouyang Q, Pablo J, et al. Pharmacological screen for activities of 12-hydroxyibogamine: A primary metabolite of the indole alkaloid ibogaine. Psychopharmacology 1996;127:10-18.
    • (1996) Psychopharmacology , vol.127 , pp. 10-18
    • Staley, J.K.1    Ouyang, Q.2    Pablo, J.3
  • 40
    • 0028932306 scopus 로고
    • Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity
    • Sweetnam PM, Lancaster J, Snowman A, et al. Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity. Psychopharmacology 1995;18:369-376.
    • (1995) Psychopharmacology , vol.18 , pp. 369-376
    • Sweetnam, P.M.1    Lancaster, J.2    Snowman, A.3
  • 42
    • 0032479991 scopus 로고    scopus 로고
    • Acute iboga alkaloid effects on extracellular serotonin (S-HT) levels in nucleus accumbens and striatum in rats
    • Wet D, Maisonneuve IM, Kuehne ME, Glick SD. Acute iboga alkaloid effects on extracellular serotonin (S-HT) levels in nucleus accumbens and striatum in rats. Brain Res 1998;800:260-268.
    • (1998) Brain Res , vol.800 , pp. 260-268
    • Wet, D.1    Maisonneuve, I.M.2    Kuehne, M.E.3    Glick, S.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.