Contralateral heat hyperalgesia induced by unilaterally intraplantar bee venom injection is produced by central changes: A behavioral study in the conscious rat

Neuroscience Letters

Volumn 284, Issue 1-2, 2000, Pages 45-48

  Chen, Hui Sheng ^a   Chen, Jun ^a   Sun, Yan Yan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Central sensitization; Contralateral heat hyperalgesia; N methyl D aspartate; Non N methyl D aspartate receptors; Spinal cord; Subcutaneous bee venom injection

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; BEE VENOM; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; HEAT SENSITIVITY; HYPERALGESIA; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SENSITIZATION; SPINAL CORD DORSAL HORN; TISSUE INJURY;

ANIMALS; BEE VENOMS; FEMALE; FOOT; FUNCTIONAL LATERALITY; HYPERALGESIA; HYPERTHERMIA, INDUCED; MALE; NOCICEPTORS; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, N-METHYL-D-ASPARTATE; REFLEX; SPINAL CORD;

EID: 0034697390     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00955-1     Document Type: Article

References (14)

1. Chen J., Luo C., Li H.L., Chen H.S. Primary hyperalgesia to mechanical and heat stimuli following subcutaneous bee venom injection into the plantar surface of hindpaw in the conscious rat: a comparative study with the formalin test. Pain. 83:1999;67-76.
2. Coderre T.J., Melzack R. Increased pain sensitivity following heat injury involves a central mechanism. Behav. Brain Res. 15:1985;259-262.
3. Donaldson L.F. Unilateral arthritis: contralateral effects. Trends Neurosci. 22:1999;495-496.
4. Fitzgerald M. Alterations in the ipsi- and contralateral afferent inputs of dorsal horn cells produced by capsaicin treatment of one sciatic nerve in the rat. Brain Res. 248:1982;97-107.
5. Kayer V., Guilbaud G. Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat. Pain. 28:1987;99-107.
6. Kissin I., Lee S.S., Bardley E.L. Effect of prolonged nerve block on inflammatory hyperalgesia in rats: prevention of late hyperalgesia. Anesthesiology. 88:1998;224-232.
7. Koltzenburg M., Wall P.D., McMahon S.B. Does the right side know what the left is doing. Trends Neurosci. 22:1999;122-127.
8. Lariviere W.R., Melzack R. The bee venom test: a new tonic-pain test. Pain. 66:1996;271-277.
9. Light A.R., Perl E.R. Reeximanition of the dorsal root projection to the spinal dorsal horn including observation on the differential termination of course and fine fibers. J. Comp. Neurol. 186:1979;117-132.
10. Lowrie M.B. Contralateral effects of peripheral nerve injury. Trends Neurosci. 22:1999;496-497.
11. Luo C., Chen J., Li H.L., Li J.S. Spatial and temporal expression of c-Fos protein in the spinal cord of anesthetized rat induced by subcutaneous bee venom injection. Brain Res. 806:1998;175-185.
12. Mapp P.I., Terenghi G., Walsh D.A., Chen S.T., Cruwys S.C., Garrett N., Kidd B.L., Polak J.M., Blake D.R. Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord. Neuroscience. 57:1993;1091-1096.
13. Zheng J.H., Chen J. Modulatory roles of the ATP P2x-purinoceptor in generation of the persistent nociception induced by subcutaneous bee venom injection in the conscious rat. Neurosci. Lett. 278:2000;41-44.
14. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:1983;109-110.