Tin-protoporphyrin potentiates arsenite-induced DNA strand breaks, chromatid breaks and kinetochore-negative micronuclei in human fibroblasts

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 452, Issue 1, 2000, Pages 41-50

  Ho, I Ching ^a   Yih, Ling Huei ^a   Kao, Cheng Yuan ^a   Lee, Te Chang ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Arsenite; Chromatid breaks; DNA strand breaks; Heme oxygenase; Kinetochore; Micronuclei; Single cell gel electrophoresis assay; Tin protoporphyrin

Indexed keywords

ANTIOXIDANT; ARSENITE SODIUM; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; HEMIN; PROTOPORPHYRIN TIN;

ARTICLE; CELL PROTECTION; CENTROMERE; CHROMATID; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYME INDUCTION; GENETIC DAMAGE; HUMAN; HUMAN CELL; MICRONUCLEUS TEST; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN FIBROBLAST; WESTERN BLOTTING;

ARSENITES; CELL SURVIVAL; CELLS, CULTURED; CHROMOSOME ABERRATIONS; COMET ASSAY; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; FIBROBLASTS; HEME OXYGENASE (DECYCLIZING); HUMANS; INFANT, NEWBORN; KINETOCHORES; MALE; METALLOPORPHYRINS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; PROTOPORPHYRINS; TUMOR CELLS, CULTURED;

EID: 0034691768     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00035-X     Document Type: Article

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