A single substitution of the insulin receptor kinase inhibits serine autophosphorylation in vitro: Evidence for an interaction between the C- terminus and the activation loop

Biochemistry

Volumn 39, Issue 24, 2000, Pages 7170-7177

  Noelle, Volker ^a,b   Tennagels, Norbert ^a,c   Klein, Helmut W ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MILTENYI BIOTEC GMBH   (Germany)

^c SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR KINASE; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; GENE OVEREXPRESSION; PEPTIDE MAPPING; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION;

HUMANS; KINETICS; MUTATION; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PHOSPHATES; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, INSULIN; RECOMBINANT PROTEINS; SERINE; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 0034691316     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991915x     Document Type: Article

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