Ofloxacin penetration into the eye after intravenous and topical administration

Retina

Volumn 17, Issue 6, 1997, Pages 535-539

  Fiscella, Richard G ^a,c   Shapiro, Michael J ^a   Solomon, Marcus J ^a   Kurtz, Ronald M ^b   Mui, Sandra ^a   Labib, Sami ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c NONE   (United States)

Author keywords

Aqueous; Intravenous; Quinolone; Vitreous

Indexed keywords

OFLOXACIN;

ADULT; AGED; ANTIBIOTIC THERAPY; AQUEOUS HUMOR; ARTICLE; CLINICAL ARTICLE; DRUG PENETRATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; MALE; MINIMUM INHIBITORY CONCENTRATION; ORAL DRUG ADMINISTRATION; PREOPERATIVE PERIOD; SURGICAL TECHNIQUE; TOPICAL DRUG ADMINISTRATION; VITRECTOMY;

EID: 0031467994     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006982-199706000-00008     Document Type: Article

References (12)

1. Todd PA, Faulds D. Ofloxacin, a reappraisal of its antimicrobial activity, pharmacology and therapeutic use. Drugs 1991;42:825-876.
2. Osato MS, Jensen HG, Trousdale MD, et al. The comparative in vitro activity of ofloxacin and selected ophthalmic antimicrobial agents against ocular bacterial isolates. Am J Ophthalmol 1989;108:380-386.
3. Gwon A, the Ofloxacin Study Group II. Ofloxacin vs tobramycin for the treatment of external ocular infection. Arch Ophthalmol 1992;110:1234-1237.
4. Gwon A, the Ofloxacin Study Group. Topical ofloxacin compared with gentamicin in the treatment of external ocular infection. Br J Ophthalmol 1992;76:714-718.
5. Donnenfeld ED, Schrier A, Perry HD, et al. Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous humor. Ophthalmology 1994;101:902-905.
6. Borrmann L, Tang-Liu D, Kann J, et al. Ofloxacin in human serum, urine, and tear film after topical application. Cornea 1992;11:226-230.
7. Matsumoto SS, Stern ME, Oda RM, et al. Effect of ofloxacin on corneal epithelial wound healing evaluated by in vitro and in vivo methods. Drug Invest 1993;6:96-103.
8. von Gunten S, Lew D, Paccolat F, et al. Aqueous humor penetration of ofloxacin given by various routes. Am J Ophthalmol 1994;117:87-89.
9. Donnenfeld ED, Perry HD, Snyder RW, et al. Intracorneal, aqueous, and vitreous humor penetration of topical and oral ofloxacin. Arch Ophthalmol 1997;115:173-176.
10. Cunha-Vaz J, Debreu JRF, Campos AJ, Figo GM. Early breakdown of the blood-retinal barrier in diabetes. Br J Ophthalmol 1975;59:649-656.
11. O'Brien TP, Maguire MG, Fink NE, et al. Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Arch Ophthalmol 1995;113:1257-1265.
12. Gatti G. Panozzo G. Effect of inflammation on intraocular penetration of intravenous ofloxacin in albino rabbits. Antimicrob Agents Chemother 1995;39:549-552.