Correlation of cyclin D1 mRNA levels with clinico-pathological parameters and clinical outcome in human breast carcinomas

International Journal of Cancer

Volumn 89, Issue 1, 2000, Pages 39-43

  Utsumi, Toshiaki ^a   Yoshimura, Noriko ^a   Maruta, Morito ^a   Takeuchi, Shinji ^b   Ando, Jiro ^c   Mizoguchi, Yoshikazu ^a   Harada, Nobuhiro ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Marumo Hospital   (Japan)

^c TOCHIGI CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; ESTROGEN RECEPTOR; MESSENGER RNA;

ADULT; AGED; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST SURGERY; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CELL CYCLE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; BREAST NEOPLASMS; CYCLIN D1; HUMANS; MIDDLE AGED; PROGNOSIS; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL ANALYSIS;

EID: 0034688134     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(20000120)89:1<39::AID-IJC7>3.0.CO;2-T     Document Type: Article

References (21)

1. ALTMAN, D.G., LAUSEN, B., SAUERBREI, W. and SCHUMACHER, M., Dangers of using "optimal" cutpoints in the evaluation of prognostic factors. J. nat. Cancer Inst., 86, 829-835 (1994).
2. 1-arrested human breast cancer cells. Oncogene, 12, 2315-2324 (1996).
3. WAF1 immunohistochemical expression. Int. J. Cancer, 74, 171-174 (1997).
4. BLOOM, H.J.G. and RICHARDSON, W.W., Histological grading and prognosis in breast cancer. A study of 1409 cases of which 359 have been followed for 15 years. Brit. J. Cancer, 11, 359-377 (1957).
5. DAKSIS, J.I., LU, R.Y., FACCHINI, L.M., MARHIN, W.W. and PENN, L.J., Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle. Oncogene, 9, 3635-3645 (1994).
6. DONNELLAN, R. and CHETTY, R., Cyclin D1 and human neoplasia. Mol. Pathol., 51, 1-7 (1998).
7. 1 cyclins in senescent human diploid fibroblasts: Accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc. nat. Acad. Sci. (Wash.), 90, 11034-11038 (1993).
8. GILLETT, C., SMITH, P., GREGORY, W., RICHARDS, M., MILLIS, R., PETERS, G. and BARNES, D., Cyclin D1 and prognosis in human breast cancer. Int. J. Cancer, 69, 92-99 (1996).
9. GRANA, X. and REDDY, E.P., Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs). Oncogene, 11, 211-219 (1995).
10. KRANENBURG, O., VAN DER EB, A.J. and ZANTEMA, A., Cyclin D1 is an essential mediator of apoplotic neuronal cell death. EMBO J., 15, 46-54 (1996).
11. MICHALIDES, R., HAGEMAN, P., VAN TINTEREN, H., HOUBEN, L., WIENTJENS, E., KLOMPMAKER, R. and PETERSE, J., A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer. Brit. J. Cancer, 73, 728-734 (1996).
12. PAGANO, M., THEODORAS, A.M., TAM, S.W. and DRAETTA, G.F., Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Gene. Develop., 8, 1627-1639 (1994).
13. PELOSIO, P., BARBARESCHI, M., BONOLDI, E., MARCHETTI, A., VERDERIO, P., CAFFO, O., BEVILACQUA, P., BORACCHI, P., BUTTITTA, F., BARBAZZA, R., DALLA PALMA, P. and GASPARINI, G., Clinical significance of cyclin D1 expression in patients with node-positive breast carcinoma treated with adjuvant therapy. Ann. Oncol., 7, 695-703 (1996).
14. 1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2. J. biol. Chem., 272, 10882-10894 (1997).
15. 1 phase in rodent fibroblasts. Gene Develop., 7, 1559-1571 (1993).
16. 1 cyclins. Cell, 73, 1059-1065 (1993).
17. SHERR, C.J., G1 phase progression: Cycling on cue. Cell, 79, 551-555 (1994).
18. UTSUMI, T., HARADA, N., MARUTA, M. and TAKAGI, Y., Presence of alternatively spliced transcripts of aromatase gene in human breast cancer. J. clin. Endocrinol. Metab., 81, 2344-2349 (1996).
19. UTSUMI, T., YOSHIMURA, N., TAKEUCHI, S., ANDO, J., MARUTA, M., MAEDA, K. and HARADA, N., Steroid sulfatase expression is an independent predictor of recurrence in human breast cancer. Cancer Res., 59, 377-381 (1999).
20. VAN DIEST, P.J., MICHALIDES, R.J.A.M., JANNINK, L., VAN DER VALK, P., PETERSE, H.L., DE JONG, J.S., MEIJER, C.J.L.M. and BAAK, J.P.A., Cyclin D1 expression in invasive breast cancer. Correlations and prognostic value. Amer. J. Pathol., 150, 705-711 (1997).
21. WATTS, C.K.W., BRADY, A., SARCEVIC, B., DEFAZIO, A., MUSGROVE, E.A. and SUTHERLAND, R.L., Antiestrogen inhibition of cell cycle progression in breast cancer cells is associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation. Mol. Endocrinol., 9, 1804-1813 (1995).