In vivo myocardial infarct size reduction by a caspase inhibitor administered after the onset of ischemia

European Journal of Pharmacology

Volumn 402, Issue 1-2, 2000, Pages 139-142

  Huang, Jing Qi ^a   Radinovic, Steve ^a   Rezaiefar, Parisa ^a   Black, Shawn C ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b PFIZER INC   (United States)

Author keywords

Apoptosis; Cardiac ischemia; Caspase inhibitor; Infarct; Reperfusion injury

Indexed keywords

CASPASE INHIBITOR; DRUG VEHICLE; N BENZYLOXYCARBONYL VALYLALANYLASPARTYLFLUOROMETHYLKETONE; N TERT BUTYLOXYCARBONYL ASPARTYLFLUOROMETHYLKETONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; CASPASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME INHIBITORS; HEMODYNAMIC PROCESSES; MALE; MYOCARDIAL INFARCTION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 0034683202     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00477-5     Document Type: Article

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