Comparison of hypoglycaemia awareness and hormonal counterregulation during induced controlled hypoglycaemia: A contribution to the assessment of hypoglycaemia awareness in type 1 (IDDM) diabetics;Vergleich des hypoglykamieempfindens und der hormonellen gegenregulation wahrend einer kontrollierten hypoglykamie: Ein beitrag zur diagnostik des hypoglykamie-unawareness-syndroms bei typ-1-diabetikern

Deutsche Medizinische Wochenschrift

Volumn 125, Issue 7, 2000, Pages 177-181

  Schneider, S ^a   Beyer, J ^a,b   Sarnighausen, H E ^a   Burchert, D ^a   Kann, P ^a   Kustner E ^a   Kunt, T ^a  

^a Klinik und Poliklinik für Innere Medizin mit Endokrinologie und Stoffwechselerkrankungen   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; GLUCAGON; HEMOGLOBIN A1C; GLYCOSYLATED HEMOGLOBIN;

ADRENALIN BLOOD LEVEL; ADULT; ARTICLE; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; GLUCAGON BLOOD LEVEL; HUMAN; HYPERINSULINEMIA; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; SYMPTOMATOLOGY; AROUSAL; AWARENESS; BLOOD; COHORT ANALYSIS; GLUCOSE CLAMP TECHNIQUE; HOMEOSTASIS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PATIENT ATTITUDE; PATIENT EDUCATION; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

ADULT; AROUSAL; AWARENESS; COHORT STUDIES; DIABETES MELLITUS, TYPE 1; EPINEPHRINE; FEMALE; GLUCAGON; GLUCOSE CLAMP TECHNIQUE; HEMOGLOBIN A, GLYCOSYLATED; HOMEOSTASIS; HUMANS; HYPOGLYCEMIA; MALE; MIDDLE AGED; PATIENT EDUCATION; SICK ROLE;

EID: 0034681220     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1024015     Document Type: Article

References (29)

1. 1 Amiel, S. A.: Hypoglycemia associated syndrome. Acta Diabetologica 35 (1998), 226-231.
2. 2 Bayer Diagnostik GmbH: Betriebsanleitung und Herstellerempfehlung über den Betrieb und Wartung von Biostatorgeräten.
3. 3 Beyer, J., S. Pies, S. Schneider: Klinik und Diagnostik des Insulinoms. In: J. R. Siewert, F. Harder, M. Rothmund; Endokrine Chirurgie, Springer Verlag, in press 1999.
4. 4 Bolli, G. B. et.al: Abnormal glucose counterregulation in insulin dependent diabetes mellitus: interaction of antiinsulin antibodies and impaired glucagons and epinephrine secretion. Diabetes 32 (1983), 143-141.
5. 5 Bolli, G. B.: Prevention and treatment of hypoglycemia unawareness in type I diabetes mellitus. Acta Diabetologica 35 (1998), 183-193.
6. 6 Boos, K. S., B. Wilmers, R. Sauerbrey, E. Schlimme: Development and performance of an automated HPLC-analizer for catecholamines. Chromatographia 24 (1987), 363.
7. 7 Boyle, P. J., S. E. Kempers, A. M. O'Connor, R. J. Nagy: Brain glucose uptake and unawareness of hypoglycemia in patients with insulin dependent diabetes mellitus. N. Engl. J. Med. 333 (1995), 977-986.
8. 8 Cryer, P. E., I. N. Fisher, H. Shamoon: Hypoglycemia. Diab. Care 17 (1994), 734-755.
9. 9 Cox, D., et.al.: A multicenter evaluation of blood glucose awareness training II. Diabetes Care 18 (1995), 523-528.
10. 10 Dagogo-Jack, S. E., P. E. Cryer: Hypoglycemic-associated autonomic failure in insulin dependent diabetes mellitus. J. Clin. Invest 91 (1993), 818-819.
11. 11 Davis, M. R., H. Shamoon: Counterregulatory adaptation to recurrent hypoglycemia in normal humans. J. Clin. Endocrinol. Metabl. 73 (1991), 955-1001.
12. 12 Davis, S. N., C. Shavers, F. Costa, R. M. Garcia: Role of cortisol in the pathogenesis of deficient counterregulation after antecedent hypoglycemia in normal humans. J. Clin. Invest. 98 (1996), 680-691.
13. 13 Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes and the development and progression of longterm complications in insulin dependent diabetes mellitus. N. Engl. J. Med. 329 (1993), 977-986.
14. 14 Diabetes Control and Complications Trial Research Group: Hypoglycemia in the Diabetes Control and Complications Trial. Diabetes 46 (1997), 1726-1731.
15. 15 Fanelli, C., L. Epifano, A. M. Rambotti et. al.: Meticulous prevention of hypoglycemia normalizes the glycemic threshold and magnitude of most of neuroendocrine responses to symptoms of and cognitin function during hypoglycemia in intensively treated patients with short term diabetes. Diabetes 42 (1993), 1683-1689.
16. 16 Fanelli, C., C. Pampanelli, C. Lalli et.al: Long term intensive therapy of IDDM patients with clinically overt autonomic neuropathy. Diabetes 46 (1997), 1172-1181.
17. 17 Frier, B. , B. Fischer et. al.: Counterregulatory hormonal response to hypoglycemia in type-I-diabetes. Diabetologia 31 (1988), 421 -429.
18. 18 Gerich, J., M. Mokan, T. Veneman et al.: Hypoglycemia unawareness. Endocrinol. Rev. 12 (1991), 356-371.
19. 19 Genovely, H., M. A. Pfeifer: The autonomic test of choice in diabetes. Diab. Metab. Rev. 4 (1988), 255-271.
20. 20 Hepburn, D., D. Eadington, A. Patrick: Symptomatic awareness of hypoglycemia. Diab. Med. 6 (1989), 586-590.
21. 21 McCall, A., L. B. Fixman, N. Fleming, K. Tornheim, W. Chick, N. B. Ruderman: Chronic hypoglycemia increases brain glucose uptake. Am. J. Physiol. 251 (1986), 442-447.
22. 22 Meyer, C, R. Großmann et.al.: Effects of autonomic neuropathy on counterregulation and awareness of hypoglycemia in type I diabetic patients. Diabetes Care 21 ( 1998), 1960-66.
23. 23. Mitrakou, A., C. Fanelli, T. Venneman et.al.: Reversibility of unawareness of hypoglycemia in patients with insulinoma. N. Engl. J. Med. 329 (1993), 834-839.
24. 24 Mitrakou, A., C. Ryan, T. Veneman et al.: Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am. J. Physiol. 260 (1991), 67-74.
25. 1c, risk of severe and mild hypoglycaemia, status of counterregulation and awareness of hypoglycaemia. Diabetologia 39 (1996), 677-686.
26. 26 Sereno Diagnostik: Arbeitsanleitung für ein Radioimmunoassay zur quantitativen Bestimmung von Glukagon. (August 1990).
27. 27 Veneman, T., A. Mitrakou, M. Mokan, P. E. Cryer, J. Gerich: Induction of hypoglycemia unawareness by asymptomatic noctural hypoglycemia. Diabetes 42 (1993), 1233-1237.
28. 28 Widom, B., D. C. Simonson: Intermittent hypoglycemia impairs glucose counterregulation. Diabetes 41 (1992), 1597-1602.
29. 29 Young, M., A. Boulton, A. Macleod, D. Wiliams, P. Senksen: A multicenter study of the prevalence of diabetic peripheral neuropathy in the U.K. hospital clinic population. Diabetologia 36 (1993), 150-154.