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Volumn 56, Issue 47, 2000, Pages 9227-9232

Synthesis of 3- and 5-endo-(6-Chloro-3-pyridoxy)-methyl-2-azabicyclo[2.2.0]hexane and 3-endo-(6-Chloro-3-pyridoxy)-methyl-2-azabicyclo[2.2.0]hex-5-ene. ABT-594 analogs

(7) Krow, Grant R a Yuan, Jing a Fang, Yuhong a Meyer, Michael D b Anderson, David J b Campbell, Jeffrey E a Carroll, Patrick J c

a Temple University (United States)

b ABBOTT LABORATORIES (United States)

c UNIVERSITY OF PENNSYLVANIA (United States)

Author keywords

Bicyclic heterocyclic compounds; Grignard reagent; Mitsunobu reaction; Stereocontrol

Indexed keywords

3 ENDO (6 CHLORO 3 PYRIDOXY) METHYL 2 AZABICYCLO[2.2.0]HEXANE; 3 ENDO (6 CHLORO 3 PYROXY) METHYL 2 AZABICYCLO[2.2.0]HEX 5 ENE; 4 HYDROXYMETHYL 1,2 DIHYDROPYRIDINE; 5 (2 AZETIDINYLMETHOXY) 2 CHLOROPYRIDINE; 5 ENDO (6 CHLORO 3 PYRIDOXY) METHYL 2 AZABICYCLO[2.2.0]HEXANE; CYTISINE; DIHYDROPYRIDINE DERIVATIVE; EPIBATIDINE; HEXANE; NICOTINIC AGENT; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYCLIZATION; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; HOT PLATE TEST; HUMAN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0034680681 PISSN: 00404020 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4020(00)00897-8 Document Type: Article

Times cited : (26)

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