Human tumor necrosis factor-α mutant RGD-V29 (F4614) shows potent antitumor activity and reduced toxicity against human tumor xenografted nude mice

Cancer Letters

Volumn 159, Issue 1, 2000, Pages 33-41

  Kuroda, Kensei ^a   Miyata, Keizo ^a   Fujita, Fumiko ^b   Koike, Masako ^b   Fujita, Masahide ^c,d,e   Nomura, Masanao ^a   Nakagawa, Shinsaku ^f   Tsutsumi, Yasuo ^f   Kawagoe, Tomoko ^a   Mitsuishi, Yachiyo ^a   Mayumi, Tadanori ^f  

^a ISHIHARA SANGYO KAISHA LTD   (Japan)

^b Experimental Cancer Chemotherapy Research Laboratory Co Ltd   (Japan)

^c Association for Anticancer Drug Search   (Japan)

^d Ueda Hospital   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f OSAKA UNIVERSITY   (Japan)

Author keywords

RGD V29 (F4614); Tumor necrosis factor ; Tumor vascular endothelial cells

Indexed keywords

F 4614; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA[5 GLYCINE 6 ASPARTIC ACID 29 VALINE]; TUMOR NECROSIS FACTOR DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SPECIFICITY; ENDOTHELIUM CELL; FIBROSARCOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; ISOELECTRIC POINT; LUNG CANCER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

EID: 0034676244     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00529-2     Document Type: Article

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