NMR line-broadening and transferred NOESY as a medicinal chemistry tool for studying inhibitors of the hepatitis C virus NS3 protease domain

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 20, 2000, Pages 2271-2274

  LaPlante, Steven R ^a   Aubry, Norman ^a   Bonneau, Pierre R ^a   Kukolj, George ^a   Lamarre, Daniel ^a   Lefebvre, Sylvain ^a   Li, Hong ^a   Llinàs Brunet, Montse ^a   Plouffe, Céline ^a   Cameron, Dale R ^a  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SERINE PROTEINASE INHIBITOR; TETRAPEPTIDE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG PROTEIN BINDING; DRUG STRUCTURE; HEPATITIS C; HEPATITIS C VIRUS; NUCLEAR MAGNETIC RESONANCE;

HEPACIVIRUS; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0034675819     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00466-2     Document Type: Article

References (16)