Inverse agonism at α2-adrenoceptors in native tissue

European Journal of Pharmacology

Volumn 398, Issue 2, 2000, Pages 185-191

  Murrin, L Charles ^a   Gerety, Moira E ^a   Happe, H Kevin ^a   Bylund, David B ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Agonist; G protein coupled receptor; GTP; Inverse; MK 912; Rauwolscine; RX821002; 2 Adrenoceptor

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; GUANOSINE TRIPHOSPHATE; RAUWOLSCINE; TRITIUM;

AGONIST; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN; CELL CULTURE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; INVERSE AGONIST; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BINDING, COMPETITIVE; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANOSINE TRIPHOSPHATE; IDAZOXAN; KINETICS; PROTEIN BINDING; QUINOLIZINES; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; TRITIUM; YOHIMBINE;

EID: 0034674747     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00317-4     Document Type: Article

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