G-protein activation by putative antagonists at mutant Thr373Lys α(2A) adrenergic receptors

British Journal of Pharmacology

Volumn 126, Issue 4, 1999, Pages 939-948

  Wurch, T ^a   Colpaert, F C ^a   Pauwels, P J ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Antagonist trafficking; G protein coupling; Intrinsic ligand activity; (2A) adrenergic receptor

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; 2 (2 ETHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 6 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 1H 3 BENZAZEPINE; ADRENALIN; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ATIPAMEZOLE; BRIMONIDINE; CLONIDINE; DELEQUAMINE; GUANABENZ; GUANINE NUCLEOTIDE BINDING PROTEIN; IDAZOXAN; INOSITOL PHOSPHATE; LYSINE; OXYMETAZOLINE; PERTUSSIS TOXIN; PROTEIN SUBUNIT; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR AFFINITY;

EID: 0032939454     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702379     Document Type: Article

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