Characterization of B-cell responses to Chlamydia trachomatis antigens in humans with trachoma

Infection and Immunity

Volumn 65, Issue 12, 1997, Pages 4958-4964

  Ghaem Maghami, Sadaf ^a   Bailey, Robin L ^b   Mabey, David C W ^b   Hay, Phillip E ^a   Mahdi, Olaimatu S M ^d   Joof, Hassan M ^d   Whittle, Hilton C ^d   Ward, Michael E ^c   Lewis, David J M ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^d MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; OUTER MEMBRANE PROTEIN;

ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CHILD; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MUCOSAL IMMUNITY; PATHOGENESIS; PRIORITY JOURNAL; TRACHOMA;

EID: 0030807908     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.12.4958-4964.1997     Document Type: Article

References (50)

1. Bailey, R. L., T. Duong, and R. Carpenter. 1996. Age dependence of incidence, duration, and clinical features of trachoma episodes in hyperendemic areas. Proc. Eur. Soc. Chlamydial Res. 3:177.
2. Bailey, R. L., T. J. Hampton, L. J. Hayes, M. E. Ward, H. C. Whittle, and D. C. W. Mabey. 1994. Polymerase chain reaction for the detection of ocular chlamydial infection in trachoma-endemic communities. J. Infect. Dis. 170: 709-712.
3. Bailey, R. L., L. Hayes, M. Pickett, H. C. Whittle, M. E. Ward, and D. C. Mabey. 1994. Molecular epidemiology of trachoma in a Gambian village. Br. J. Ophthalmol. 78:813-817.
4. Bailey, R. L., M. J. Holland, H. C. Whittle, and D. C. Mabey. 1995. Subjects recovering from human ocular chlamydial infection have enhanced lymphoproliferative responses to chlamydial antigens compared with those of persistently diseased controls. Infect. Immun. 63:389-392.
5. Bailey, R. L., M. Kajbaf, H. C. Whittle, M. E. Ward, and D. C. Mabey. 1993. The influence of local antichlamydial antibody on the acquisition and persistence of human ocular chlamydial infection: IgG antibodies are not protective. Epidemiol. Infect. 111:315-324.
6. Bobo, L., N. Novak, H. Mkocha, S. Vitale, S. West, and T. C. Quinn. 1996. Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma. Infect. Immun. 64:3273-3279.
7. Brunham, R. C., C. C. Kuo, L. Cles, and K. K. Holmes. 1983. Correlation of host immune response with quantitative recovery of Chlamydia trachomatis from the human endocervix. Infect. Immun. 39:1491-1494.
8. Brunham, R. C., I. W. Maclean, B. Binns, and R. W. Peeling. 1985. Chlamydia trachomatis: its role in tubal infertility. J. Infect. Dis. 152:1275-1282.
9. Brunham, R. C., R. Peeling, I. Maclean, M. L. Kosseim, and M. Paraskevas. 1992. Chlamydia trachomatis-associated ectopic pregnancy: serologic and histologic correlates. J. Infect. Dis. 165:1076-1081.
10. Brunham, R. C., R. Peeling, I. Maclean, J. McDowell, K. Persson, and S. Osser. 1987. Postabortal Chlamydia trachomatis salpingitis: correlating risk with antigen-specific serological responses and with neutralization. J. Infect. Dis. 155:749-755.
11. Brunham, R. C., and R. W. Peeling. 1994. Chlamydia trachomatis antigens: role in immunity and pathogenesis. Infect. Agents Dis. 3:218-233.
12. Castello-Branco, L. R. R., G. E. Griffin, T. A. Poulton, G. Dougan, and D. J. M. Lewis. 1994. Characterisation of the circulating T cell response after oral immunisation of human volunteers with cholera toxin B subunit. Vaccine 12:65-72.
13. Castello-Branco, L. R. R., G. E. Griffin, T. A. Poulton, and D. J. M. Lewis. 1993. T cell responses after oral immunisation of humans with cholera toxin B subunit. Clin. Sci. 84:6-7.
14. Cui, Z. D., D. Tristram, L. J. LaScolea, T. Kwiatkowski, Jr., S. Kopti, and P. L. Ogra. 1991. Induction of antibody response to Chlamydia trachomatis in the genital tract by oral immunization. Infect. Immun. 59:1465-1469.
15. Czerkinsky, C., A. M. Svennerholm, and J. Holmgren. 1993. Induction and assessment of immunity at enteromucosal surfaces in humans: implications for vaccine development. Clin. Infect. Dis. 16:S106-S116.
16. Czerkinsky, C., A. M. Svennerholm, M. Quiding, R. Jonsson, and J. Holmgren. 1991. Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans. Infect. Immun. 59:996-1001.
17. Czerkinsky, C. C., L. A. Nilsson, H. Nygren, O. Ouchterlony, and A. Tarkowski. 1983. A solid phase enzyme linked immunospot (ELISPOT) assay for enumeration of specific antibody secreting cells. J. Immunol. Methods 65:109-121.
18. Ford, W. L. 1975. Lymphocyte migration and immune responses. Prog. Allergy 19:1-59.
19. Hall, J. G. 1980. An essay on lymphocyte circulation and the gut. Monogr. Allergy 16:100-111.
20. Ho, F., J. E. Lortan, I. C. MacLennan, and M. Khan. 1986. Distinct short-lived and long-lived antibody-producing cell populations. Eur. J. Immunol. 16:1297-1301.
21. Holmgren, J., and C. Czerkinsky. 1992. Cholera as a model for research on mucosal immunity and development of oral vaccines. Curr. Opin. Immunol. 4:387-391.
22. Holt, P. G., J. D. Sedgwick, G. A. Stewart, C. O'Leary, and K. Krska. 1984. ELISA plaque assay for the detection of antibody secreting cells: observations on the nature of the solid phase and on variations in plaque diameter. J. Immunol. Methods 74:1-7.
23. Johansson, E., M. Fredriksson, M. Lindblad, H. Caldwell, C. Czerkinsky, and J. Holmgren. 1995. Cholera toxin B subunit as mucosal immunogens and carrier/adjuvent molecules for inducing genital immunity. Clin. Immunol. Immunopathol. 76:S43-S44.
24. Johansson, M., K. Schon, M. Ward, and N. Lycke. 1997. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response. Infect. Immun. 65:1032-44.
25. Kantele, A., H. Arvilommi, and I. Jokinen. 1986. Specific immunoglobulin-secreting human blood cells after peroral vaccination against Salmonella typhi. J Infect. Dis. 153:1126-31.
26. Lewis, D. J. M., P. Novotny, G. Dougan, and G. E. Griffin. 1991. The early cellular and humoral immune response to primary and booster oral immunisation with cholera toxin B subunit. Eur. J. Immunol. 21:2087-2094.
27. Magee, D. M., D. M. Williams, J. G. Smith, C. A. Bleicker, B. G. Grubbs, J. Schachter, and R. G. Rank. 1995. Role of CD8 T cells in primary Chlamydia infection. Infect. Immun. 63:516-521.
28. Malinverni, R. 1996. The role of cytokines in chlamydial infections. Curr. Opin. Infect. Dis. 9:150-155.
29. Manclark, C. R., B. D. Meade, and D. G. Burstyn. 1986. Serological response to Bordetella pertussis, p. 388-394. In N. R. Rose, H. Friedman, and J. L. Fahey (ed.). Manual of clinical immunology, 3 ed. American Society for Microbiology, Washington, D.C.
30. McDermott, M. R., and J. Bienenstock. 1979. Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissues. J. Immunol. 122:1892-1898.
31. Mestecky, J. 1988. Immunobiology of IgA. Am. J. Kidney Dis. 12:378-383.
32. Morrison, R. P. 1991. Chlamydial hsp60 and the immunopathogenesis of chlamydial disease. Semin. Immunol. 3:25-33.
33. Pal, S., T. J. Fielder, E. M. Peterson, and L. M. de la Maza. 1994. Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumunitis biovar of Chlamydia trachomatis. Infect. Immun. 62:3354-3362.
34. Pal, S., H. R. Taylor, R. B. Huneke, R. A. Prendergast, and J. A. Whittum-Hudson. 1992. Frequency of antigen-specific B cells during experimental ocular Chlamydia trachomatis infection. Infect. Immun. 60:5294-5297.
35. Peeling, R. W., R. L. Bailey, D. J. Conway, M. J. Holland, E. Dillon, A. E. Campbell, and D. C. W. Mabey. 1996. Antibody response to the chlamydial heat shock protein 60 is associated with scarring trachoma. Proc. Eur. Soc. Chlamydial Res. 3:73.
36. Pickett, M. A., M. E. Ward, and I. N. Clarke. 1988. High-level expression and epitope localization of the major outer membrane protein of Chlamydia trachomatis serovar L1. Mol. Microbiol. 2:681-685.
37. Quiding-Jarbrink, M., M. Lakew, I. Nordstrom, J. Banchereau, E. Butcher, J. Holmgren, and C. Czerkinsky. 1995. Human circulating specific antibody-forming cells after systemic and mucosal immunizations: differential homing commitments and cell surface differentiation markers. Eur. J. Immunol. 25:322-327.
38. Rahman, M. U., A. P. Hudson, and H. R. Schumachcr. 1992. Chlamydia and Reiter's syndrome (reactive arthritis). Rheum. Dis. Clin. North Am. 18:67-79.
39. Salmi, M., D. P. Andrew, E. C. Butcher, and S. Jalkanen. 1995. Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms. J. Exp. Med. 181:137-149.
40. Schachter, J., and C. R. Dawson. 1990. The epidemiology of trachoma predicts more blindness in the future. Scand. J. Infect. Dis. Suppl. 69:55-62.
41. Sedgwick, J. D., and P. G. Holt. 1983. A solid phase immunoenzymatic technique for the enumeration of specific antibody secreting cells. J. Immunol. Methods 57:301-309.
42. Sowa, S., J. Sowa, L. H. Collier, and W. A. Blyth. 1969. Trachoma vaccine field trials in The Gambia. J. Hyg. (London) 67:699-717.
43. Sprent, J., and I). F. Tough. 1994. Lymphocyte life-span and memory. Science 265:1395-1400.
44. Treharne, J. D. 1985. The community epidemiology of trachoma. Rev. Infect. Dis. 7:760-764.
45. VanCott, J. L., H. F. Staats, D. W. Pascual, M. Roberts, S. N. Chatfield, M. Yamamoto, M. Coste, P. B. Carter, H. Kiyono, and J. R. McGhee. 1996. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokincs following oral immunization with live recombinant Salmonella. J. Immunol. 156:1504-1514.
46. Wang, S. P., and J. T. Grayston. 1967. Pannus with experimental trachoma and inclusion conjunctivitis agent infection of Taiwan monkeys. Am. J. Ophthalmol. 63(Suppl.):1133-1145.
47. Wang, S. P., J. T. Grayston, and E. R. Alexander. 1967. Trachoma vaccine studies in monkeys. Am. J. Ophthalmol. 63(Suppl.):1615-1630.
48. Ward, M. E. 1995. The immunobiology and immunopathology of chlamydial infections. APMIS 103:769-796.
49. Watson, R. R., J. D. Mull, A. B. MacDonald, S. E. D. Thompson, and S. E. Bear. 1973. Immunity to chlamydial infections of the eve. II. Studies of passively transferred serum antibody in resistance to infection with guinea pig inclusion conjunctivitis. Infect. Immun. 7:597-599.
50. Williams, D. M., J. Schachter, and B. Grubbs. 1987. Role of natural killer cells in infection with the mouse pneumonitis agent (murine Chlamydia trachomatis). Infect. Immun. 55:223-226.