HIV-1 Tat represses transcription from the mannose receptor promoter

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 7035-7041

  Caldwell, R L ^a   Egan, B S ^a   Shepherd, V L ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMINOID; ANTIGEN; LUCIFERASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNOSE RECEPTOR; TRANSACTIVATOR PROTEIN; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; PHAGOCYTOSIS; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR DOWN REGULATION; REPORTER GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0034671817     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.7035     Document Type: Article

References (54)

1. Biology of animal lectins
2. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment downregulation by cytokines and bacterial products
3. The mannose receptor is a pattern recognition receptor involved in host defense
4. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules
5. Ingestion of Candida albicans down-regulates mannose receptor expression on rat macrophages
6. Down-regulation of mannose receptors on macrophages after infection with Leishmania donovani
7. Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation
8. Viral strategies of immune evasion
9. HIV-1 regulatory/accessory genes. Keys to unraveling viral and host cell biology
10. Repression of MHC class I gene promoter activity by two-exon Tat of HIV
11. HIV Tat represses transcription through Sp1-like elements in the basal promoter
12. HIV-1 Tat binds TAF(II)250 and represses TAF(II)250-dependent transcription of major histocompatibility class I genes
13. 2-microglobulin promoter
14. On the role of the second coding exon of the HIV-1 Tat protein in virus replication and MHC class I downregulation
15. Regulation of HIV expression mechanisms of action of Tat and Rev
16. Control of RNA initiation and elongation at the HIV-1 promoter
17. The human immunodeficiency virus type-1 (HIV-1) Tat protein and bcl-2 gene expression
18. The Tat protein of HIV-1 induces tumor necrosis factor-alpha production implications for HIV-1-associated neurological diseases
19. HIV type 1 Tat protein inhibits interleukin 12 production by human peripheral blood mononuclear cells
20. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes
21. Activation of monocytes by HIV-Tat treatment is mediated by cytokine expression
22. Human immunodeficiency virus type 1 tat gene up-regulates interleukin-4 receptors on a human B-lymphoblastoid cell line
23. HIV-1 tat induces the expression of a new hematopoietic cell-specific transcription factor and down-regulates MIP-1α gene expression in activated T-cells
24. HIV-1 tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes
25. + T cells
26. A negative regulatory element of the macrophage-specific human mannose receptor gene represses its expression in nonmyeloid cells
27. PU 1 and USF are required for macrophage-specific mannose receptor promoter activity
28. Site directed mutagenesis by overlap extension using the polymerase chain reaction
29. Equine infectious anemia virus transactivator is a homeodomain-type protein
30. An autocrine loop of HIV type 1 Tat protein responsible for the improved survival/proliferation capacity of permanently Tat-transfected cells and required for optumal human immunodeficiency virus type 1 long terminal repeat transactivation activity
31. Paracrine activation of the HIV-1 LTR promoter by the viral Tat protein is mechanistically similar to trans-activation within a cell
32. Involvement of mannose receptors in cytokine interleukin-1β (IL-1β), IL-6 and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1β (MIP-1β), MIP-2, and KC responses, caused by attachment of Candida albicans to macrophages
33. Secretion of TNF-α by alveolar macrophages in response to Candida albicans mannan
34. Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan
35. The mannose receptor mediates induction of IFN-α in peripheral blood dendritic cells by enveloped RNA and DNA viruses
36. HIV-1 attachment another look
37. From negative factor to a critical role in virus pathogenesis the changing fortunes of Nef
38. In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor
39. Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat
40. Start site selection by Sp1 in the TATA-less human Ha-ras promoter
41. Transcription from a TATA-less promoter requires a multisubunit TFIID complex
42. Murine macrophage mannose receptor promoter is regulated by the transcription factors PU 1 and Sp1
43. Contributions of the TATA box sequence to rate-limiting steps in transcription initiation by RNA polymerase II
44. 133 phosphorylation and activation of CREB transcription factor in both Jurkat lymphoblastoid T cells and primary peripheral blood mononuclear cells
45. Extracellular HIV type 1 Tat protein induces CD69 expression through NF-κB activation possible correlation with cell surface Tat-binding proteins
46. Upregulation of c-Fos in activated T lymphoid and monocytic cells by human immunodeficiency virus-1 Tat protein
47. Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1
48. HIV-1 tat immunosuppression via TGF-β1 reduction
49. Charactenzation of the murine macrophage mannose receptor demonstration that the downregulation of receptor expression mediated by interferon-γ occurs at the level of transcription
50. Cellular uptake of the Tat protein from human immunodeficiency virus
51. Nuclear and nucleolar targeting sequences of c-erb-A, c-myc, N-myc, p53, HSP70, and HIV tat proteins
52. 3 integrins and by mobilizing sequestered basic fibroblast growth factor
53. HIV-1 Tat protein mimicry of chemokines
54. Human immunodeficiency virus type 1 genome activation induced by human T-cell leukemia virus type 1 Tax protein is through cooperation of NF-κB and Tat