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Volumn 383, Issue 2, 2000, Pages 197-205

1α,25-dihydroxy-16-ene-23-yne-vitamin D3 and 1α,25-dihydroxy-16-ene-23-yne-20-epi-vitamin D3: Analogs of 1α,25-dihydroxyvitamin D3 that resist metabolism through the C-24 oxidation pathway are metabolized through the C-3 epimerization pathway

(9) Reddy, G S a Rao, D S a Siu Caldera, M L a Astecker, N a Weiskopf, A b Vouros, P c Sasso, G J d Manchand, P S d Uskokovic, M R d

a BROWN UNIVERSITY (United States)

b Cetek Corproation (United States)

c NORTHEASTERN UNIVERSITY (United States)

d HOFFMANN LA ROCHE INC (United States)

Author keywords

1 ,25(OH)2 16 ene 23 yne 20 epi D3; 1 ,25(OH)2 3 epi D3; 1 ,25(OH)2 16 ene 23 yne D3; 1 ,25(OH)2D3; C 3 epimerization; Metabolism

Indexed keywords

1ALPHA,25 DIHYDROXY 16 ENE 23 YNE 20 EPI VITAMIN D3; 1ALPHA,25 DIHYDROXY 16 ENE 23 YNE VITAMIN D3; CALCITRIOL; UNCLASSIFIED DRUG; 9,10 SECOCHOLESTA 5,7,10(19),16 TETRAEN 23 YNE 1,3,25 TRIOL; DRUG DERIVATIVE; OXYGEN; RO 23-7553;

ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE METABOLISM; HORMONE STRUCTURE; HORMONE SYNTHESIS; HYDROXYLATION; MOUSE; NONHUMAN; OSTEOSARCOMA CELL; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; ANIMAL; CELL CULTURE; CHEMISTRY; MASS FRAGMENTOGRAPHY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSTEOSARCOMA; RAT; TIME;

ANIMALIA;

ANIMALS; CALCITRIOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MAGNETIC RESONANCE SPECTROSCOPY; OSTEOSARCOMA; OXYGEN; RATS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0034669367 PISSN: 00039861 EISSN: None Source Type: Journal
DOI: 10.1006/abbi.2000.2074 Document Type: Article

Times cited : (26)

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