A 20-epi side chain restores growth-regulatory and transcriptional activities of an A ring-modified hybrid analog of 1α,25-dihydroxyvitamin D3 without increasing its affinity to the vitamin D receptor

Journal of Cellular Biochemistry

Volumn 63, Issue 2, 1996, Pages 149-161

  Peleg, Sara ^a   Liu, Yan Yun ^a   Reddy, Saravathy ^a   Horst, Ronald L ^b   White, M Christina ^c   Posner, Gary H ^c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NATIONAL ANIMAL DISEASE CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

1 ,25 dihydroxyvitamin D3; 20 epi analogs; growth inhibition; hybrid analogs; transcription; vitamin D receptor

Indexed keywords

CALCITRIOL RECEPTOR; COLECALCIFEROL; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DOSE RESPONSE; DRUG EFFECT; DRUG RECEPTOR BINDING; GROWTH INHIBITION; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; TRANSCRIPTION REGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCITRIOL; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DNA; HUMANS; OSTEOCALCIN; PROTEIN CONFORMATION; RECEPTORS, CALCITRIOL; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0029853866     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19961101)63:2<149::AID-JCB3>3.0.CO;2-Y     Document Type: Article

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