Surprises from Drosophila: Genetic mechanisms of synaptic development and plasticity

Brain Research Bulletin

Volumn 53, Issue 5, 2000, Pages 501-511

  Featherstone, David E ^a   Broadie, Kendal ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Drosophila; Glutamate decarboxylase; Latheo; Neuromuscular junction; Synaptogenesis

Indexed keywords

GLUTAMATE DECARBOXYLASE; PROTEIN LATHEO; UNCLASSIFIED DRUG;

CELL INTERACTION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; MUTANT; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SYNAPTOGENESIS; TECHNIQUE;

ANIMALS; CELL COMMUNICATION; DROSOPHILA; MODELS, ANIMAL; NERVOUS SYSTEM; NEUROMUSCULAR JUNCTION; NEURONAL PLASTICITY; SYNAPSES;

EID: 0034668722     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(00)00383-X     Document Type: Review

References (104)

1. The role of neural activity in synaptic development and its implications for adult brain function
2. The genome sequence of Drosophila melanogaster
3. Development of the giant fiber neuron of Drosophila melanogaster
4. Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila
5. Drosophila UNC-13 is essential for synaptic transmission
6. Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvae
7. Electrophysiological development of central neurons in the Drosophila embryo
8. Development of larval body wall muscles
9. A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function
10. GABA-induced motility of spinal neuroblasts develops along a ventrodorsal gradient and can be mimicked by agonists of GABAA and GABAB receptors
11. Clearance of glutamate inside the synapse and beyond
12. A role for PS integrins in morphological growth and synaptic function at the postembryonic neuromuscular junction of Drosophila
13. Segment polarity genes in neuroblast formation and identity specification during Drosophila neurogenesis
14. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
15. Latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis
16. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
17. Forward and reverse genetic approaches to synaptogenesis
18. Activity-dependent development of the neuromuscular synapse during Drosophila embryogenesis
19. Innervation directs receptor synthesis and localization in Drosophila embryo synaptogenesis
20. Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila
21. Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function
22. Synaptogenesis in Drosophila; Coupling genetics and electrophysiology
23. Development of larval muscle properties in the embryonic myotubes of Drosophila melanogaster
24. Development of the embryonic neuromuscular synapse of Drosophila melanogaster
25. Slit proteins; Key regulators of axon guidance, axonal branching, and cell migration
26. Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg
27. Morphological plasticity of motor axons in Drosophila mutants with altered excitability
28. Neurogenesis in Drosophila; An historical perspective and some prospects
29. A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis
30. Assembly of functionally active Drosophila origin recognition complex from recombinant proteins
31. 'Painting' the target; How local molecular cues define synaptic relationships
32. Fasciclin III as a synaptic target recognition molecule in Drosophila
33. Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila
34. Synapse-specific control of synaptic efficacy at the terminals of a single neuron
35. Genetic dissection of structural and functional components of synaptic plasticity. III. CREB is necessary for presynaptic functional plasticity
36. Physiology and biochemistry of Drosophila learning mutants
37. Glutamate receptor expression regulates quantal size and quantal content at the Drosophila neuromuscular junction
38. Gene discovery in Drosophila; New insights for learning and memory
39. Presynaptic glutamic acid decarboxylase (GAD) is required for induction of the postsynaptic receptor field at a glutamatergic synapse
40. The long and the short of long-term memory-A molecular framework
41. Clustering membrane proteins; It's all coming together with the PSD-95/SAP90 protein family
42. A Drosophila homolog of the yeast origin recognition complex
43. Assembly and maturation of the Drosophila larval neuromuscular junction
44. Glia development in the embryonic CNS of Drosophila
45. Dynamics of nerve-muscle interaction in developing and mature neuromuscular junctions
46. The Drosophila tumor suppressor gene, dlg, is involved in structural plasticity at a glutamatergic synapse
47. The homeobox gene repo is required for the differentiation and maintenance of glia function in the embryonic nervous system of Drosophila melanogaster
48. Neuropil pattern formation and regulation of cell adhesion molecules in Drosophila optic lobe development depend on synaptobrevin
49. Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro
50. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein
51. Mediatophore, a protein supporting quantal acetylcholine release
52. GAL4-responsive UAS-tau as a tool for studying the anatomy and development of the Drosophila central nervous system
53. Inhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular origin
54. L-glutamate as an excitatory transmitter at the Drosophila larval neuromuscular junction
55. Stereotypic morphology of glutamatergic synapses on identified muscle cells of Drosophila larvae
56. Transmitter leakage from motor nerve endings
57. Drosophila larval neuromuscular junction; Molecular components and mechanisms underlying synaptic plasticity
58. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation
59. Homophilic synaptic target recognition mediated by immunoglobulin-like cell adhesion molecule Fasciclin III
60. Modifications of seizure susceptibility in Drosophila
61. The origin, location, and projections of the embryonic abdominal motorneurons of Drosophila
62. Synaptic plasticity; Fastening synapses by adhesion
63. Rapid, activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons
64. GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis
65. A genetic analysis of synaptic development; Pre- and postsynaptic dCBP control transmitter release at the Drosophila NMJ
66. A simple chemosensory response in Drosophila and the isolation of acj mutants in which it is affected
67. Formation of the neuromuscular junction; Molecules and mechanisms
68. The role of GABA during development of the outer retina in the rabbit
69. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein
70. The role of cell adhesion molecules in synaptic plasticity and memory
71. Connectin; A homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila
72. Seizures and failures in the giant fiber pathway of Drosophila bang-sensitive paralytic mutants
73. Genetic analysis of glutamate receptors in Drosophila reveals a retrograde signal regulating presynaptic transmitter release
74. Isolation of mutations affecting neural circuitry required for grooming behavior in Drosophila melanogaster
75. latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant
76. Integrating bits and pieces; Synapse structure and formation in Drosophila embryos
77. Presynaptic development at the Drosophila neuromuscular junction; Assembly and localization of presynaptic active zones
78. Ultrastructural correlates of neuromuscular junction development
79. Llatheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity
80. A single growth cone is capable of integrating simultaneously presented and functionally distinct molecular cues during target recognition
81. ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP
82. Distribution of functional glutamate receptors in cultured embryonic Drosophila myotubes revealed using focal release of L-glutamate from caged compound by laser
83. Neural activity affects distribution of glutamate receptors during neuromuscular junction formation in Drosophila embryos
84. Development of the vertebrate neuromuscular junction
85. Clonal analysis of Drosophila embryonic neuroblasts; Neural cell types, axon projections and muscle targets
86. Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth
87. Genetic dissection of structural and functional components of synaptic plasticity. II. Fasciclin II controls presynaptic structural plasticity
88. Synapse formation by hippocampal neurons from agrin-deficient mice
89. Homeostasis of synaptic transmission in Drosophila with genetically altered nerve terminal morphology
90. Coordination of legs during straight walking and turning in Drosophila melanogaster
91. The ultrastructural interactions of identified pre- and postsynaptic cells during synaptic target recognition in Drosophila embryos
92. Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects
93. The molecular biology of axon guidance
94. Genes that control neuromuscular specificity in Drosophila
95. Concomitant alterations of physiological and developmental plasticity in Drosophila CaM kinase II-inhibited synapses
96. Repo encodes a glial-specific homeo domain protein required in the Drosophila nervous system
97. CREB as a memory modulator; Induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila
98. Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila
99. Synaptic plasticity in Drosophila memory and hyperexcitable mutants; Role of cAMP cascade
100. Altered nerve terminal arborization and synaptic transmission in Drosophila mutants of cell adhesion molecule fasciclin I
101. Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade
102. Watching a synapse grow; Noninvasive confocal imaging of synaptic growth in Drosophila