Accomodation of S-cis-tamoxifen-N2-guanine adduct within a bent and widened DNA minor groove

Journal of Molecular Biology

Volumn 302, Issue 2, 2000, Pages 375-391

  Shimotakahara, Sakurako ^a   Gorin, Andrey ^a   Kolbanovskiy, Alexander ^b   Kettani, Abdelali ^a   Hingerty, Brian E ^c   Amin, Shantu ^d   Broyde, Suse ^b   Geacintov, Nicholas ^b   Patel, Dinshaw J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

^d AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

Covalent tamoxifen complex; Groove binding; Localized helical perturbation; Widened minor groove

Indexed keywords

GUANINE DERIVATIVE; OLIGONUCLEOTIDE; TAMOXIFEN; TAMOXIFEN DERIVATIVE;

AMINO ACID SEQUENCE; ARTICLE; BASE PAIRING; BREAST CANCER; DNA ADDUCT; DRUG CONFORMATION; DRUG STRUCTURE; ENDOMETRIUM CANCER; HUMAN; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN CONFORMATION; STEREOISOMERISM; STRUCTURE ANALYSIS;

EID: 0034665637     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4071     Document Type: Article

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