Cutting edge: Differential constitutive expression of functional receptors for lysophosphatidic acid by human blood lymphocytes

Journal of Immunology

Volumn 164, Issue 10, 2000, Pages 4996-4999

  Goetzl, Edward J ^a   Kong, Yvonne ^a   Voice, Julia K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 2; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; SPHINGOSINE 1 PHOSPHATE;

ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0034657254     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.10.4996     Document Type: Article

References (22)

1. Spiegel, S., and S. Milstein. 1995. Sphingolipid metabolites: members of a new class of lipid second messengers. J. Membr. Biol. 146:225.
2. Moolenaar, W. H., O. Kranenburg, F. R. Postma, and G. Zondag. 1997. Lysophosphatidic acid: G protein signaling and cellular responses. Curr. Opin. Cell Biol. 9:168.
3. Goetzl, E. J., and S. An. 1998. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12:1589.
4. An, S., E. J. Goetzl, and H. Lee. 1998. Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate. J. Cell. Biochem. Suppl. 30/31:147.
5. Hecht, J. H., J. A. Weiner, S. R. Post, and J. Chun. 1996. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell Biol. 135:1071.
6. Lee, M.-J., J. R. Van Brocklyn, S. Thangada, C. H. Liu, A. R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279:1552.
7. Lynch, K. R., and D.-S. Im. 1999. Life on the Edg. Trends Pharmacol. Sci. 20:473.
8. Goetzl, E. J., and K. R. Lynch, eds. 2000. Lysophospholipid and eicosanoid mediators in physiology and diseases. Ann. NY Acad. Sci. In press.
9. Tigyi, G., D. L. Dyer, and R. Miledi. 1994. Lysophosphatidic acid possesses dual action in cell proliferation Proc. Natl. Acad. Sci. USA 91:1908.
10. Cuvillier, O., D. S. Rosenthal, M. E. Smulson, and S. Spiegel. 1998. Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. J. Biol. Chem. 273:2910.
11. Goetzl, E. J., Y. Kong, and B. Mei. 1999. Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. J. Immunol. 162:2049.
12. Goetzl, E. J., Y. Kong, and J. S. Kenney. 1999. Lysophospholipid enhancement of human T cell sensitivity to diphtheria toxin by increased expression of heparin-binding epidermal growth factor. Proc. Assoc. Am. Physicians 111:259.
13. Stam, J. C., F. Michiels, R. A. van der Kammen, W. H. Moolenaar, and J. G. Collard. 1998. Invasion of T lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. EMBO J. 17:4066.
14. Goetzl, E. J., Y. Kong, and J. K. Voice. 2000. Lysophosphatidic acid and sphingosine 1-phosphate stimulation of Jurkat T cell transmigration of a model basement membrane. FASEB J. In press (Abstr.).
15. An, S., T. Bleu, O. G. Hallmark, and E. J. Goetzl. 1998. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J. Biol. Chem. 273:7906.
16. An, S., T. Bleu, Y. Zheng, and E. J. Goetzl. 1998. Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization. Mol. Pharmacol. 54:881.
17. Goetzl, E. J., H. Dolezalova, Y. Kong, and L. Zeng. 1999. Dual mechanisms for lysophospholipid induction of proliferation of human breast carcinoma cells. Cancer Res. 59:4732.
18. Bandoh, K., J. Aoki, H. Hosono, S. Kobayashi, T. Kobayashi, K. Murakami-Murofushi, M. Tsugimoto, H. Arai, and K. Inoue. 1999. Molecular cloning and characterization of a novel G protein-coupled receptor, EDG-7, for lysophosphatidic acid. J. Biol. Chem. 274:27776.
19. Goetzl, E. J., H. Dolezalova, Y. Kong, Y.-L. Hu, R. B. Jaffe, K. R. Kalli, and C. A. Conover. 1999. Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. Cancer Res. 59:5370.
20. Olivera, A., T. Kohama, L. Edsall, V. Nava, O. Cuvillier, S. Poulton, and S. Spiegel. 1999. Sphingosine kinase expression increases intracellular sphingosine 1-phosphate and promotes cell growth and survival. J. Cell Biol. 147:545
21. Hedin, K. E., M. P. Bell, C. J. Huntoon, L. M. Kamitz, and D. J. McKean. 1999. Gi proteins use a novel β/γ- and ras-independent pathway to activate extracellular signal-regulated kinase and mobilize AP-1 transcription factors in Jurkat T lymphocytes. J. Biol. Chem. 274:19992.
22. Gupta, S. K., C. Gallego, G. L. Johnson, and L. E. Heasley. 1992. MAP kinase (p42) is constitutively activated in gip2 and src transformed rat 1a fibroblasts. J. Biol. Chem. 267:7987.