The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: Implications for substrate channeling in a bifunctional enzyme

Structure

Volumn 8, Issue 1, 2000, Pages 35-46

  Kohls, Darcy ^a   Sulea, Traian ^b   Purisima, Enrico O ^b   MacKenzie, Robert E ^a   Vrielink, Alice ^a  

^a Montreal Joint Centre for Structural Biology   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Bifunctional enzyme; Formiminotransferase cyclodeaminase; Substrate channeling; Tetrahydrofolate; X ray diffraction

Indexed keywords

ENZYME; FOLINIC ACID; FORMIMINOGLUTAMIC ACID; GLUTAMIC ACID; TETRAHYDROFOLIC ACID;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; STEREOISOMERISM; STRUCTURE ANALYSIS;

EID: 0034650448     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00078-2     Document Type: Article

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