Perinatal exposure to zidovudine - Benefits and risks

New England Journal of Medicine

Volumn 343, Issue 11, 2000, Pages 803-805

  Mofenson, L M ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ZIDOVUDINE;

DRUG INDICATION; DRUG USE; EDITORIAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PERINATAL DRUG EXPOSURE; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS;

CLINICAL APPROACH/SOURCE; HEALTH CARE AND PUBLIC HEALTH; PREGNANT WOMEN; PROFESSIONAL PATIENT RELATIONSHIP; RISKS AND BENEFITS;

ANTI-HIV AGENTS; DISEASE TRANSMISSION, VERTICAL; FEMALE; HEART VENTRICLES; HIV INFECTIONS; HUMANS; INFANT, NEWBORN; LONGITUDINAL STUDIES; MITOCHONDRIA, HEART; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANT WOMEN; PRENATAL CARE; PRENATAL EXPOSURE DELAYED EFFECTS; RISK ASSESSMENT; VENTRICULAR FUNCTION, LEFT; ZIDOVUDINE;

EID: 0034648733     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200009143431110     Document Type: Editorial

References (15)

1. Reduction of maternal-infant transmission of human immunodeficicncy virus type 1 with zidovudine treatment
2. Advances and research directions in the prevention of mother-to-child HIV-1 transmission
3. Trends in perinatal transmission of HIV/AIDS in the United States
4. Public Health Service Task Force recommendations for the use of antiretroviral drugs in pregnant women infected with HIV-1 for maternal health and for reducing perinatal HIV-1 transmission in the United States
5. Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero
6. Short-course zidovudine for perinatal HIV-1 transmission in Bangkok Thailand: A randomised controlled trial
7. Short-course oral zidovudine for prevention of mother-to-child transmission of HIV-1 in Abidjan, Cote D'Ivoire: A randomised trial
8. 6-Month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Cote d'Ivoire and Burkina Faso: A double-blind placebo-controlled multicentre trial
9. Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women
10. Lack of tumors in infants with perinatal HIV-1 exposure and fetal/neonatal exposure to zidovudine
11. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues
12. Fetal mitochondrial heart avid skeletal muscle damage in Etythrocebus patas monkeys exposed in utero to 3'azido-3'-deoxythymidinc
13. Absence of cardiac toxicity of zidovudine in infants