The effect of periaqueductal gray lesions on responses to age-specific threats in infant rats

Developmental Brain Research

Volumn 120, Issue 2, 2000, Pages 191-198

  Wiedenmayer, Christoph P ^a   Goodwin, Gregory A ^b   Barr, Gordon A ^a,c  

^a New York State Psychiatric Institute ^*  (United States)

^b SKIDMORE COLLEGE   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Analgesia; Immobility; Lesion; Periaqueductal gray; Rat; Ultrasonic vocalization

Indexed keywords

AGE; ANALGESIA; ANIMAL MODEL; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SOCIAL ISOLATION; THREAT; VOCALIZATION;

AGING; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BODY WEIGHT; FEAR; FEMALE; MALE; MATERNAL DEPRIVATION; PAIN; PAIN MEASUREMENT; PERIAQUEDUCTAL GRAY; RATS; RATS, LONG-EVANS; REACTION TIME; SOCIAL BEHAVIOR; SOCIAL ISOLATION; STRESS, PSYCHOLOGICAL; VOCALIZATION, ANIMAL;

ANIMALIA;

EID: 0034646859     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(00)00009-2     Document Type: Article

References (43)

1. R. Bandler, P. Carrive, A. Depaulis, Emerging principles of organization of the midbrain periaqueductal gray matter, in: A. Depaulis, R. Bandler (Eds.), The Midbrain Periaqueductal Gray Matter, Vol. 213, Plenum, New York, 1991, pp. 1-9.
2. R. Bandler, M.T. Shipley, Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?, TINS 17 (1994) 379-389.
3. G.A. Barr, Behavioral effects of opiates during development, in: M.W. Miller (Ed.), Development of the Central Nervous System, Effects of Alcohol and Opiates, Wiley-Liss, New York, 1992, pp. 221-254.
4. G.A. Barr, D.Y. Miya, W. Paredes, Analgesic effects of intraventricular and intrathecal injection of morphine and ketocyclazocine in the infant rat, Brain Res. 584 (1992) 83-91.
5. G.A. Barr, S. Wang, Mu and delta opiates induce analgesia when injected into the PAG or NRM in preweanling rats, Regul. Pept. 54 (1994) 17-18.
6. M.M. Behbehani, Functional characteristics of the midbrain periaqueductal gray, Prog. Neurobiol. 46 (1995) 575-605.
7. A.J. Beitz, Anatomic and chemical organization of descending pain modulation systems, in: C.E. Short, A. Van Poznak (Eds.), Animal Pain, Churchill-Livingstone, New York, 1992, pp. 31-62.
8. P.S.F. Bellgowan, F.J. Helmstetter, Neural systems for the expression of hypoalgesia during nonassociative fear, Behav. Neurosci. 110 (1996) 727-736.
9. R.C. Bolles, P.J. Woods, The ontogeny of behaviour in the albino rat, Anim. Behav. 12 (1964) 427-441.
10. P. Carrive, The periaqueductal gray and defensive behavior: functional representation and neuronal organization, Behav. Brain Res. 58 (1993) 27-47.
11. B.M. De Oca, J.P. DeCola, S. Maren, M.S. Fanselow, Distinct regions of the periaqueductal gray are involved in the acquisition and expression of defensive responses, J. Neurosci. 18 (1998) 3426-3432.
12. M.S. Fanselow, The midbrain periaqueductal gray as a coordinator of action in response to fear and anxiety, in: A. Depaulis, R. Bandler (Eds.), The Midbrain Periaqueductal Gray Matter, Vol. 213, Plenum, New York, 1991, pp. 151-173.
13. H.L. Fields, A.I. Basbaum, Central nervous system mechanisms of pain modulation, in: P.D. Wall, R. Melzack (Eds.), Textbook of Pain, Churchill-Livingstone, Edinburgh, 1999, pp. 309-329.
14. G.A. Goodwin, G.A. Barr, Behavioral and heart rate effects of infusing kainic acid into the dorsal midbrain during early development in the rat, Dev. Brain Res. 107 (1998) 11-20.
15. G. A. Goodwin, G.A. Barr, Developmental changes in the behavioral and autonomic effects of kappa opioid receptor stimulation in the midbrain periaqueductal gray (submitted for publication).
16. M. Graham, R. Letz, Within-species variation in the development of ultrasonic signaling of preweanling rats, Dev. Psychobiol. 12 (1979) 129-136.
17. F.J. Helmstetter, J. Landeira-Fernandez, Conditional hypoalgesia is attenuated by naltrexone applied to the periaqueductal gray, Brain Res. 537 (1990) 88-92.
18. F.J. Helmstetter, S.A. Tershner, Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses, J. Neurosci. 14 (1994) 7099-7108.
19. M.A. Hofer, Multiple regulators of ultrasonic vocalization in the infant rat, Psychoneuroendocrinology 21 (1996) 203-217.
20. U. Jürgens, The role of the periaqueductal grey in vocal behaviour, Behav. Brain Res. 62 (1994) 107-117.
21. P. Kehoe, E.M. Blass, Behaviorally functional opioid systems in infant rats: II. Evidence for pharmacological, physiological, and psychological mediation of pain and stress, Behav. Neurosci. 100 (1986) 624-630.
22. P. Kehoe, E.M. Blass, Opioid-mediation of separation distress in 10-day-old rats: reversal of stress with maternal stimuli, Dev. Psychobiol. 19 (1986) 385-398.
23. J.J. Kim, R.A. Rison, M.S. Fanselow, Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear, Behav. Neurosci. 107 (1993) 1093-1098.
24. S.-I. Kyuhou, H. Gemba, Two vocalization-related subregions in the midbrain periaqueductal gray of the guinea pig, NeuroReport 9 (1998) 1607-1610.
25. J.E. LeDoux, J. Iwata, P. Cicchetti, D.J. Reis, Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear, J. Neurosci. 8 (1988) 2517-2529.
26. J.M. Liebman, D.J. Mayer, J.C. Liebeskind, Mesencephalic central gray lesions and fear-motivated behavior in rats, Brain Res. 23 (1970) 353-370.
27. P. Martin, P. Bateson, Measuring Behaviour, 2nd edn., Cambridge Univ. Press, Cambridge, 1993.
28. J.A. Mennella, H. Moltz, Infanticide in rats: male strategy and female counter-strategy, Physiol. Behav. 42 (1988) 19-28.
29. E. Noirot, Ultrasounds in young rodents: II. Changes with age in albino rats, Anim. Behav. 16 (1968) 129-134.
30. L. Paul, J. Kupferschmidt, Killing of conspecific and mouse young by male rats, J. Comp. Physiol. Psychol. 88 (1975) 755-763.
31. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 4th edn., Academic Press, San Diego, 1998.
32. J. Sandkühler, The organization and function of endogenous antinociceptive systems, Prog. Neurobiol. 50 (1996) 49-81.
33. W.P. Smotherman, R.W. Bell, W.A. Hershberger, G.D. Coover, Orientation to rat pup cues: effects of maternal experimental history, Anim. Behav. 26 (1978) 265-273.
34. L.P. Spear, E.K. Enters, M.A. Aswad, M. Louzan, Drug and environmentally induced manipulations of the opiate and serotonergic systems alter nociception in neonatal pups, Behav. Neural Biol. 44 (1985) 1-22.
35. L.K. Takahashi, Developmental expression of defensive responses during exposure to conspecific adults in preweanling rats (Rattus norvegicus), J. Comp. Psychol. 106 (1992) 69-77.
36. L.K. Takahashi, J.G. Turner, N.H. Kalin, Development of stress-induced responses in preweanling rats, Dev. Psychobiol. 24 (1991) 341-360.
37. E. Thiels, J.R. Alberts, C.P. Cramer, Weaning in rats: II. Pup behavior patterns, Dev. Psychobiol. 23 (1990) 495-510.
38. L.A. Tive, G.A. Barr, Analgesia from the periaqueductal gray in the developing rat: focal injections of morphine or glutamate and effects of intrathecal injection of methysergide or phentolamine, Brain Res. 584 (1992) 92-109.
39. C.-D. Walker, K.A. Scribner, C.S. Cascio, The pituitary-adrenocortical system of neonatal rats is responsive to stress throughout development in a time-dependent and stressor-specific fashion, Endocrinology 128 (1991) 1385-1395.
40. C.P. Wiedenmayer, G.A. Barr, Development of defensive behavior and analgesia in rat pups to infanticidal threat, in: A.B. Society (Ed.), 1998 Annual Meeting, Animal Behavior Society, Carbondale, IL, 1998.
41. C.P. Wiedenmayer, G.A. Barr, Ontogeny of defensive behavior and analgesia in rat pups exposed to an adult male rat, Physiol. Behav. 63 (1998) 261-269.
42. C.P. Wiedenmayer, G.A. Barr, μ Opioid receptors in the ventrolateral periaqueductal gray mediate stress-induced analgesia but not immobility in rat pups, Behav. Neurosci. 114 (2000) 125-136.
43. Y. Yajima, Y. Hayashi, N. Yoshii, The midbrain central gray substance as a highly sensitive structure for the production of ultrasonic vocalization in the rat, Brain Res. 198 (1980) 446-452.