Behavioral and heart rate effects of infusing kainic acid into the dorsal midbrain during early development in the rat

Developmental Brain Research

Volumn 107, Issue 1, 1998, Pages 11-20

  Goodwin, G A ^a   Barr, G A ^a,b  

^a Columbia Univ Coll Phys Surgs 722 W 168th St ^*  (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Central gray; Defensive response; Development; Excitatory amino acid; Heart rate; Kainate; Rat; Ultrasonic vocalization

Indexed keywords

EXCITATORY AMINO ACID; KAINIC ACID; KAINIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BODY TEMPERATURE; BRAIN DEVELOPMENT; CONTROLLED STUDY; ESCAPE BEHAVIOR; HEART RATE; IMMOBILIZATION; LOCOMOTION; MESENCEPHALON; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; TOPOGRAPHY; VOCALIZATION;

ANIMALIA;

EID: 0032540258     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(97)00209-5     Document Type: Article

References (20)

1. Adolf E.F. Capacities for regulation of heart rate in fetal, infant, and adult rats. Am. J. Physiol. 209:1965;1095-1105.
2. Bell R.W. Ultrasonic control of maternal behavior: developmental implications. Am. Zool. 19:1979;413-418.
3. Blanchard D.C., Williams G., Lee E.M.C., Blanchard R.J. Taming of wild Rattus norvegicus by lesions of the mesencephalic central gray. J. Physiol. Psychol. 9:1981;157-163.
4. Brandão M.L., Cardoso S.H., Melo L.L., Motta V., Coimbra N.C. Neural substrate of defensive behavior in the midbrain tectum. Neurosci. Biobehav. Rev. 18:1994;339-346.
5. Carden S.E., Davachi L., Hofer M.A. U50,488 increases ultrasonic vocalizations in 3-, 10-, and 18-day-old rat pups in isolation and the home cage. Dev. Psychobiol. 27:1994;65-83.
6. Dean P., Redgrave P., Westby W.M. Event or emergency? Two response systems in the mammalian superior colliculus. Trends Neurosci. 12:1989;137-147.
7. Depaulis A., Keay K.A., Bandler R. Longitudinal neuronal organization of defensive reactions in the midbrain periaqueductal gray region of the rat. Exp. Brain Res. 90:1992;307-318.
8. Fernandez de Molina A., Hunsperger R.W. Organization of the subcortical system governing defense and flight reactions in the cat. J. Physiol. 160:1962;200-213.
9. Graeff F.G. Neuroanatomy and neurotransmitter regulation of defensive behaviors and related emotions in mammals. Braz. J. Med. Biol. Res. 27:1994;811-829.
10. Hård E., Engel J., Musi B. The ontogeny of defensive reactions in the rat: influence of the monoamine transmission systems. Scand. J. Psychol. 1:1982;90-96. Suppl.
11. Heller A., Hutchens J.L., Kirby M.L., Karapas F., Fernandez C. Stereotaxic electrode placement in the neonatal rat. J. Neurosci. Methods. 1:1979;41-76.
12. Hilton S.M., Redfern W.W. A search for brain stem cell groups integrating the defense reaction in the rat. J. Physiol. 378:1986;213-228.
13. Hofer M.A., Reiser M.F. The development of cardiac rate regulation in preweanling rats. Psychosom. Med. 31:1960;372-388.
14. Jürgens U. The role of the periaqueductal gray in vocal behavior. Behav. Brain Res. 62:1994;107-117.
15. Lovick T.A. The periaqueductal gray-rostral medulla connection in the defence reaction: efferent pathways and descending control mechanisms. Behav. Brain Res. 58:1993;19-25.
16. Noirot E. Ultrasounds in young rodents: II. Changes with age in albino rats. Anim. Behav. 16:1968;129-134.
17. Quigley K.S., Shair H.N., Meyers M.M. Parasympathetic control of heart period during early postnatal development in the rat. J. Auton. Nerv. Sys. 59:1996;75-82.
18. Schenberg L.C., Vasquez E.C., Barcellos da Costa M. Cardiac baroreflex dynamics during the defence reaction in freely moving rats. Brain Res. 621:1993;50-58.
19. Tive L.A., Barr G.A. Analgesia from the periaqueductal gray in the developing rat: focal injections of morphine or glutamate and effects of intrathecal injection of methysergide or phentolamine. Brain Res. 584:1992;92-109.
20. Goodwin, Barr, submitted.