Antihistamine terfenadine potentiates NMDA receptor-mediated calcium influx, oxygen radical formation, and neuronal death

Brain Research

Volumn 880, Issue 1-2, 2000, Pages 17-27

  Díaz Trelles, Ramón ^a   Novelli, Antonello ^a,b   Vega, Jose A ^b   Marini, Ann ^c   Fernández Sánchez, M Teresa ^a  

^a UNIVERSIDAD DE OVIEDO   (Spain)

^b UNIVERSITY OF OVIEDO   (Spain)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

Cultured cerebellar neurons.; Excitatory aminoacid receptors; Histamine; Intracellular calcium; Reactive oxygen species; Terfenadine

Indexed keywords

ALPHA TOCOPHEROL; CHLORPHENIRAMINE; CYCLIC GMP; DIZOCILPINE; EXCITOTOXIN; GLUTAMIC ACID; HISTAMINE H1 RECEPTOR ANTAGONIST; MELATONIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OXATOMIDE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; TERFENADINE; TRIPROLIDINE;

ANIMAL CELL; ANIMAL TISSUE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CEREBELLUM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; RNA SYNTHESIS;

EID: 0034644860     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02627-5     Document Type: Article

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