A novel type of mutation in the cysteine rich domain of the RET receptor causes ligand independent activation

Oncogene

Volumn 19, Issue 30, 2000, Pages 3445-3448

  Arlt, D H ^a   Baur, B ^a   Wagner, B ^b   Hoppner W ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Additional cysteine 634; Ligand independent dimerization; MEN 2; RET proto oncogene

Indexed keywords

AMINO ACID; CYSTEINE; DISULFIDE; LIGAND; ONCOPROTEIN; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; BASE PAIRING; CANCER SUSCEPTIBILITY; CHROMOSOME DUPLICATION; CODON; CONTROLLED STUDY; DIMERIZATION; GENE ACTIVATION; GENE INSERTION SEQUENCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOUSE; NONHUMAN; ONCOGENE RET; PRIORITY JOURNAL; SHORT SURVEY; SIPPLE SYNDROME;

ANIMALIA;

EID: 0034644196     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203688     Document Type: Short Survey

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