Development of an efficient intermediate, α-[2-(trimethylsilyl)ethoxy]-2-N-[2-(trimethylsilyl)ethoxycarbonyl]folic acid, for the synthesis of folate (γ)-conjugates, and its application to the synthesis of folate-nucleoside conjugates

Journal of Organic Chemistry

Volumn 65, Issue 16, 2000, Pages 5016-5021

  Nomura, Makoto ^a,b   Shuto, Satoshi ^a   Matsuda, Akira ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID; FOLIC ACID DERIVATIVE; NUCLEOSIDE;

ARTICLE; CONJUGATE; SYNTHESIS;

FOLIC ACID; MODELS, CHEMICAL; NUCLEOSIDES; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE;

EID: 0034637570     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo000132a     Document Type: Article

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