Disruption of the 14-3-3 binding site within the B-raf kinase domain uncouples catalytic activity from PC12 cell differentiation

Journal of Biological Chemistry

Volumn 275, Issue 6, 2000, Pages 3803-3809

  MacNicol, Melanie C ^a   Muslin, Anthony J ^b   MacNicol, Angus M ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHOSERINE; RAF PROTEIN; UNCOUPLING PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CATALYSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE DISRUPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; RAT; XENOPUS;

14-3-3 PROTEINS; ANIMALS; BINDING SITES; CELL DIFFERENTIATION; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NERVE GROWTH FACTOR; OOCYTES; PC12 CELLS; PHOSPHORYLATION; PROGESTERONE; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS C-RAF; RATS; TYROSINE 3-MONOOXYGENASE; XENOPUS;

ANIMALIA;

EID: 0034635482     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.6.3803     Document Type: Article

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