Attempts to control haemonchosis in grazing ewes by vaccination with gut membrane proteins of the parasite

Veterinary Parasitology

Volumn 92, Issue 1, 2000, Pages 15-23

  Kabagambe, E K ^a   Barras, S R ^a   Li, Y ^a   Pena M T ^a   Smith, W D ^b   Miller, J E ^a,c  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^c Louisiana Agric Exp Stn L ^*  (United States)

Author keywords

Ewes; Haemonchus contortus; Integral membrane proteins; Pasture challenge; Vaccine

Indexed keywords

ADJUVANT; ALBENDAZOLE; ANTIGEN; IVERMECTIN; LEVAMISOLE; MEMBRANE PROTEIN; VACCINE;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FEMALE; HAEMONCHUS CONTORTUS; HEMATOCRIT; INTESTINE; NONHUMAN; SHEEP; STATISTICAL ANALYSIS; TRICHOSTRONGYLOSIS; UNITED STATES; VACCINATION; WORM EGG;

ANIMALS; ANTIBODIES, HELMINTH; DIGESTIVE SYSTEM; HAEMONCHIASIS; HAEMONCHUS; HELMINTH PROTEINS; PARASITE EGG COUNT; SHEEP; SHEEP DISEASES; VACCINATION;

HAEMONCHUS CONTORTUS; OVIS; OVIS ARIES;

EID: 0034633356     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4017(00)00272-7     Document Type: Article

References (17)

1. Bahirathan M., Miller J.E., Barras S.R., Kearney M.T. Susceptibility of Suffolk and Gulf Coast Native suckling lambs to naturally acquired strongylate nematode infection. Vet. Parasitol. 65:1996;259-268.
2. Conder G.A., Campbell W.C. Chemotherapy of nematode infections of veterinary importance, with special reference to drug resistance. Adv. Parasitol. 35:1995;1-84.
3. Miller J.E., Bahirathan M., Lemarie S.L., Hembry F.G., Kearney M.T., Barras S.R. Epidemiology of gastrointestinal nematode parasitism in Suffolk and Gulf Coast Native sheep with special emphasis on relative susceptibility to Haemonchus contortus infection. Vet. Parasitol. 74:1998;55-74.
4. Newton S.E. Progress on vaccination against Haemonchus contortus. Int. J. Parasitol. 25:1995;1281-1289.
5. Newton S.E., Morrish L.E., Martin P.J., Montague P.E., Rolph T.P. Protection against multiple drug-resistant and geographically distant strains of Haemonchus contortusvaccination with H11, a gut membrane-derived protective antigen. Int. J. Parasitol. 25:1995;511-521.
6. Newton S.E., Munn E.A. The development of vaccines against gastro-intestinal nematode parasites particularly Haemonchus contortus. Parasitol. Today. 15:1999;116-122.
7. Prichard R.K. Anthelmintic resistance. Int. J. Parasitol. 54:1994;259-268.
8. Sangster N.C. Anthelmintic resistance: past, present and future. Int. J. Parasitol. 29:1999;115-124.
9. Schallig H.D.F.H., Van Leeuwen M.A.W., Hendrikx W.M.L. Immune responses of Texel sheep to excretory/secretory products of adult Haemonchus contortus. Parasitology. 108:1994;351-357.
10. Schallig H.D.F.H., Van Leeuwen M.A.W. Protective immunity to the blood feeding nematode Haemonchus contortusinduced by vaccination with parasite low molecular weight antigens. Parasitology. 114:1997;293-299.
11. Smith W.D. Prospects for vaccines of helminth parasites of grazing ruminants. Int. J. Parasitol. 29:1999;17-24.
12. Smith W.D., Smith S.K. Evaluation of aspects of protection afforded to sheep immunised with a gut membrane protein of Haemonchus contortus. Res. Vet. Sci. 55:1993;1-9.
13. Smith W.D., Smith S.K., Murray J.M. Protection studies with integral membrane fractions of Haemonchus contortus. Parasite Immunol. 16:1994;231-241.
14. Smith S.K., Pettit D., Newlands G.F.J., Redmond D.L., Skuce P.J., Knox D.P., Smith W.D. Further immunisation and biochemical studies with a protective antigen complex from the microvillar membrane of the intestine of Haemonchus contortus. Parasite Immunol. 21:1999;187-199.
15. Tavernor A.S., Smith T.S., Langford C.F., Munn E.A., Graham M. Vaccination of young Dorset lambs against haemonchosis. Parasite Immunol. 14:1992;645-655.
16. Tavernor A.S., Smith T.S., Langford C.F., Graham M., Munn E.A. Immune response of Clun Forest sheep to vaccination with membrane glycoproteins from Haemonchus contortus. Parasite Immunol. 14:1992;671-675.
17. Waller P.J. The development of anthelmintic resistance in ruminant livestock. Acta Trop. 56:1994;233-243.