Enhanced expression of silencer of death domains (SODD/BAG-4) in pancreatic cancer

Biochemical and Biophysical Research Communications

Volumn 271, Issue 2, 2000, Pages 409-413

  Ozawa, Fumiaki ^a   Friess, Helmut ^a   Zimmermann, Arthur ^a   Kleeff, Jörg ^a   Büchler, Markus W ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Apoptosis; BAG 4; Death domain; Gastrointestinal cancer; mRNA; Pancreatic cancer; Self association; Silencer of death domains; TNF ; TNFR 1

Indexed keywords

CELL PROTEIN; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; PANCREAS CANCER; PRIORITY JOURNAL;

EID: 0034630736     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2610     Document Type: Article

References (28)

1. Ashkenazi, A., and Dixit, V. M. (1998) Death receptors: Signaling and modulation. Science 281, 1305-1308.
2. Ashkenazi, A., and Dixit, V. M. (1999) Apoptosis control by death and decoy receptors. Curr. Cell. Biol. 11, 255-260.
3. Tschopp, J., Martinon, F., and Hofmann, K. (1999) Apoptosis: Silencing the death receptors. Curr. Biol. 9, 381-384.
4. Nagata, S. (1997) Apoptosis by death factor. Cell 88, 355-356.
5. Yeh, W. C., Shahinian, A., Speiser, D., Kraunus, J., Billia, F., Wakeham, A., de la Pompa, J. L., Ferrick, D., Hum, B., Iscove, N., Ohashi, P., Rothe, M., Goeddel, D. V., and Mak, T. W. (1997) Early lethality, functional NK-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7, 715-725.
6. Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z., and Leder, P. (1998) The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 8, 297-303.
7. Boldin, M. P., Mett, I. L., Varfolomeev, E. E., Chumakov, I., Shemer-Avni, Y., Camonis, J. H., and Wallach, D. (1995) Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J. Biol. Chem. 6, 387-391.
8. Hsu, H., Huang, J., Shu, H. B., Baichwal, V., and Goeddel, D. V. (1999) TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4, 387-396.
9. Jiang, Y., Woronicz, J. D., Liu, W., and Goeddel, D. V. (1999) Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science 283, 543-546.
10. Frisch, S. M. (1999) Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis. Curr. Biol. 9, 1047-1049.
11. Raitano, A. B., Scuderi, P., and Korc, M. (1990) Binding and biological effect of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells. Pancreas 5, 267-277.
12. Ungefroren, H., Voss, M., Jansen, M., Roeder, C., Henne-Bruns, D., Kremer, B., and Kalthoff, H. (1998) Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis. Cancer Res. 58, 1741-1749.
13. Kleeff, J., Kornmann, M., Sawhney, H., and Korc, M. (2000) Actinomycin D inhibits growth and induces apoptosis in pancreatic cancer cells. Int. J. Cancer, in press.
14. Guo, X. Z., Friess, H., di Mola, F. F., Heinicke, J. M., Abou-Shady, M., Graber, H. U., Baer, H. U., Zimmermann, A., Korc, M., and Buchler, M. W. (1998) KAI1, a new metastasis suppressor gene, is reduced in metastatic hepatocellular carcinoma. Hepatology 28, 1481-1488.
15. di Mola, F. F., Friess, H., Martignoni, M. E., Di Sebastiano, P., Zimmermann, A., Innocenti, P., Graber, H., Gold, L. I., Korc, M., and Buchler, M. W. (1999) Connective tissue growth factor is a regulator for fibrosis in human chronic pancreatitis. Ann. Surg. 230, 63-71.
16. Büchler, M. W., Friess, H., Schultheiss, K. H., Gebhardt, C., Kubel, R., Muhrer, K. H., Winkelmann, M., Wagener, T., Klapdor, R., and Kaul, M. (1991) A randomized controlled trail of adjuvant immunotherapy (murine monoclonal antibody 494/32) in resectable pancreatic cancer. Cancer 68, 1507-1512.
17. Friess, H., Büchler, M. W., Krüger, M., and Beger, H. G. (1992) Treatment of duct carcinoma of pancreas with the LH-RH-analogue buserelin. Pancreas 7, 516-521.
18. Friess, H., Lu, Z., Graber, H. U., Zimmermann, A., Adler, G., Korc, M., Schmid, R. M., and Buchler, M. W. (1998) Bax, but not bcl-2, influences the prognosis of human pancreatic cancer. Gut 43, 414-421.
19. Friess, H., Lu, Z., Andrén-Sandberg, A., Berberat, P., Zimmermann, A., Adler, G., Schmid, R., and Buchler, M. W. (1998) Moderate activation of the apoptosis inhibitor bcl-xL deteriorates the prognosis in pancreatic cancer. Ann. Surg. 228, 780-787.
20. Graber, H. U., Friess, H., Zimmermann, A., Korc, M., Adler, G., Schmid, R., and Buchler, M. W. (1999) Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells. J. Gastrointest. Surg. 3, 74-81.
21. Landowski, T. H., Qu, N., Buyuksal, I., Painter, J. S., and Dalton, W. S. (1997) Mutations in the Fas antigen in patients with multiple myeloma. Blood 90, 4266-4270.
22. Sheridan, J. P., Marsters, S. A., Pitti, R. M., Gurney, A., Skubatch, M., Baldwin, D., Ramakrishnan, L., Gray, C. L., Baker, K., Wood, W. I., Goddard, A. D., Godowski, P., and Ashkenazi, A. (1997) Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277, 818-821.
23. Thompson, C. B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
24. Takayama, S., Xie, Z., and Reed, J. C. (1999) An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. J. Biol. Chem. 274, 781-786.
25. Takayama, S., Krajewski, S., Krajewska, M., Kitada, S., Zapata, J. M., Kochel, K., Knee, D., Scudiero, D., Tudor, G., Miller, G. J., Miyashita, T., Yamada, M., and Reed, J. C. (1998) Expression and location of Hsp70/Hsc-binding anti-apoptotic protein BAG-1 and its variants in normal tissues and tumor cell lines. Cancer Res. 15, 3116-3131.
26. Takayama, S., Bimston, D. N., Matsuyama, S., Freeman, B. C., Aime-Sempe, C., Xie, Z., Morimoto, R. I., and Reed, J. C. (1997) BAG-1 modulates the chaperone activity of Hsp70/Hsc70. EMBO J. 16, 4887-4896.
27. Jaattela, M., (1999) Escaping cell death: Survival proteins in cancer. Exp. Cell. Res. 10, 30-43.
28. Jaattela, M., Wissing, D., Bauer, P. A., and Li, G. C. (1992) Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. EMBO J. 11, 3507-3512.