메뉴 건너뛰기




Volumn 11, Issue 3, 2000, Pages 487-503

A phase I study of intralesional administration of an adenovirus vector expressing the HSV-1 thymidine kinase gene (AdV.RSV-TK) in combination with escalating doses of ganciclovir in patients with cutaneous metastatic malignant melanoma

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; VIRUS VECTOR;

EID: 0034628523     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430340050015950     Document Type: Article
Times cited : (30)

References (58)
  • 1
    • 9044238842 scopus 로고    scopus 로고
    • Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The cytomegalovirus retreatment trial. The Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group
    • ACTG/SOCA. (1996). Combination foscarnet and ganciclovir therapy vs monotherapy for the treatment of relapsed cytomegalovirus retinitis in patients with AIDS. The Cytomegalovirus Retreatment Trial. The Studies of Ocular Complications of AIDS Research Group in Collaboration with the AIDS Clinical Trials Group. Arch. Ophthalmol. 114(1), 23-33.
    • (1996) Arch. Ophthalmol. , vol.114 , Issue.1 , pp. 23-33
  • 2
    • 0028802721 scopus 로고
    • Systemic treatments for advanced cutaneous melanoma
    • discussion 1163-4, 1167-8
    • ANDERSON, C.M., BUZAID, A.C., and LEGHA, S.S. (1995). Systemic treatments for advanced cutaneous melanoma. Oncology (Huntingt). 9(11), 1149-58; discussion 1163-4, 1167-8.
    • (1995) Oncology (Huntingt) , vol.9 , Issue.11 , pp. 1149-1158
    • Anderson, C.M.1    Buzaid, A.C.2    Legha, S.S.3
  • 3
    • 0019461784 scopus 로고
    • A multifactorial analysis of melanoma: III. Prognostic factors in melanoma patients with lymph node metastases (stage II)
    • BALCH, C.M., SOONG, S.J., MURAD, T.M., INGALLS, A.L., and MADDOX, W.A. (1981a). A multifactorial analysis of melanoma: III. Prognostic factors in melanoma patients with lymph node metastases (stage II). Ann. Surg. 193(3), 377-88.
    • (1981) Ann. Surg. , vol.193 , Issue.3 , pp. 377-388
    • Balch, C.M.1    Soong, S.J.2    Murad, T.M.3    Ingalls, A.L.4    Maddox, W.A.5
  • 4
    • 0021077073 scopus 로고
    • A multifactorial analysis of melanoma. IV. Prognostic factors in 200 melanoma patients with distant metastases (stage III)
    • BALCH, C.M., SOONG, S.J., MURAD, T.M., SMITH, J.W., MADDOX, W.A., and DURANT, J.R. (1983b). A multifactorial analysis of melanoma. IV. Prognostic factors in 200 melanoma patients with distant metastases (stage III). J. Clin. Oncol. 1(2), 126-34.
    • (1983) J. Clin. Oncol. , vol.1 , Issue.2 , pp. 126-134
    • Balch, C.M.1    Soong, S.J.2    Murad, T.M.3    Smith, J.W.4    Maddox, W.A.5    Durant, J.R.6
  • 5
    • 0028238797 scopus 로고
    • Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells
    • BALZARINI, J., BOHMAN, C., WALKER, R.T., and DE CLERCQ, E. (1994). Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Mol. Pharmacol. 45(6), 1253-8.
    • (1994) Mol. Pharmacol. , vol.45 , Issue.6 , pp. 1253-1258
    • Balzarini, J.1    Bohman, C.2    Walker, R.T.3    De Clercq, E.4
  • 6
    • 0028323573 scopus 로고
    • Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors
    • BARBA, D., HARDIN, J., SADELAIN, M., and GAGE, F.H. (1994). Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc. Natl. Acad. Sci. USA 91(10), 4348-52.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , Issue.10 , pp. 4348-4352
    • Barba, D.1    Hardin, J.2    Sadelain, M.3    Gage, F.H.4
  • 7
    • 0008921627 scopus 로고
    • Long-term results of intralesional BCG for locally advanced recurrent melanoma
    • BAUER, R., KOPALD, K., LEE, J., WONG, J., and MORTON, D. (1990). Long-term results of intralesional BCG for locally advanced recurrent melanoma. Proc. Amer. Soc. Clin. Oncol. 9, 276.
    • (1990) Proc. Amer. Soc. Clin. Oncol. , vol.9 , pp. 276
    • Bauer, R.1    Kopald, K.2    Lee, J.3    Wong, J.4    Morton, D.5
  • 8
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy
    • BI, W.L., PARYSEK, L.M., WARNICK, R., and STAMBROOK, P.J. (1993). In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum. Gene Ther. 4(6), 725-31.
    • (1993) Hum. Gene Ther. , vol.4 , Issue.6 , pp. 725-731
    • Bi, W.L.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 9
    • 0021807545 scopus 로고
    • Metabolic activation of the nucleoside analog 9-[(2-hydroxy-1- (hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus
    • BIRON, K.K., STANAT, S.C., SORRELL, J.B., FYFE, J.A., KELLER, P.M., LAMBE, C.U., and NELSON, D.J. (1985). Metabolic activation of the nucleoside analog 9-[(2-hydroxy-1- (hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus. Proc. Natl. Acad. Sci. USA 82(8), 2473-7.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , Issue.8 , pp. 2473-2477
    • Biron, K.K.1    Stanat, S.C.2    Sorrell, J.B.3    Fyfe, J.A.4    Keller, P.M.5    Lambe, C.U.6    Nelson, D.J.7
  • 13
    • 0028237365 scopus 로고
    • Adenovirus-mediated in vivo gene transfer
    • discussion 101-3
    • BRODY, S.L., and CRYSTAL, R.G. (1994). Adenovirus-mediated in vivo gene transfer. Ann. N.Y. Acad. Sci. 716, 90-101; discussion 101-3.
    • (1994) Ann. N.Y. Acad. Sci. , vol.716 , pp. 90-101
    • Brody, S.L.1
  • 14
    • 0002890136 scopus 로고
    • Clinical safety of intravenous ganciclovir
    • S.A. Spector, ed., (Marcel-Dekker, Inc., New York)
    • BUHLES, W.C. (1991b). Clinical safety of intravenous ganciclovir. In Ganciclovir Therapy for Cytomegalovirus Infection, S.A. Spector, ed., (Marcel-Dekker, Inc., New York), pp. 31-69.
    • (1991) Ganciclovir Therapy for Cytomegalovirus Infection , pp. 31-69
    • Buhles, W.C.1
  • 15
    • 0024040718 scopus 로고
    • Ganciclovir treatment of life-or sight-threatening cytomegalovirus infection: Experience in 314 immunocompromised patients
    • BUHLES, W.C., JR., MASTRE, B.J., TINKER, A.J., STRAND, V., and KORETZ, S.H. (1988a). Ganciclovir treatment of life-or sight-threatening cytomegalovirus infection: experience in 314 immunocompromised patients. Rev. Infect. Dis. 10 Suppl 3, S495-506.
    • (1988) Rev. Infect. Dis. , vol.10 , Issue.SUPPL. 3
    • Buhles W.C., Jr.1    Mastre, B.J.2    Tinker, A.J.3    Strand, V.4    Koretz, S.H.5
  • 16
    • 0028202066 scopus 로고
    • Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
    • CHEN, S.H., SHINE, H.D., GOODMAN, J.C., GROSSMAN, R.G., and WOO, S.L.C. (1994). Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl. Acad. Sci. USA 91(8), 3054-7.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , Issue.8 , pp. 3054-3057
    • Chen, S.H.1    Shine, H.D.2    Goodman, J.C.3    Grossman, R.G.4    Woo, S.L.C.5
  • 18
    • 0029161615 scopus 로고
    • The "bystander effect": Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice
    • COLOMBO, B.M., BENEDETTI, S., OTTOLENGHI, S., MORA, M., POLLO, B., POLI, G., and FINOCCHIARO, G. (1995). The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice. Hum. Gene Ther. 6(6), 763-72.
    • (1995) Hum. Gene Ther. , vol.6 , Issue.6 , pp. 763-772
    • Colombo, B.M.1    Benedetti, S.2    Ottolenghi, S.3    Mora, M.4    Pollo, B.5    Poli, G.6    Finocchiaro, G.7
  • 19
    • 0018615446 scopus 로고
    • Racial differences in melanoma incidence
    • CROMBIE, I.K. (1979). Racial differences in melanoma incidence. Br. J. Cancer 40(2), 185-93.
    • (1979) Br. J. Cancer , vol.40 , Issue.2 , pp. 185-193
    • Crombie, I.K.1
  • 20
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • CULVER, K.W., RAM, Z., WALLBRIDGE, S., ISHII, H., OLDFIELD, E.H., and BLAESE, R.M. (1992). In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors [see comments]. Science 256(5063), 1550-2.
    • (1992) Science , vol.256 , Issue.5063 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 21
    • 85041132416 scopus 로고
    • Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML
    • DEISSEROTH, A.B., ZU, Z., CLAXTON, D., HANANIA, E.G., FU, S., ELLERSON, D., GOLDBERG, L., THOMAS, M., JANICEK, K., ANDERSON, W.F., and et al. (1994). Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML. Blood. 83(10), 3068-76.
    • (1994) Blood , vol.83 , Issue.10 , pp. 3068-3076
    • Deisseroth, A.B.1    Zu, Z.2    Claxton, D.3    Hanania, E.G.4    Fu, S.5    Ellerson, D.6    Goldberg, L.7    Thomas, M.8    Janicek, K.9    Anderson, W.F.10
  • 22
    • 0008886159 scopus 로고
    • Spontaneous regression of malignant melanoma
    • T.C. Everson and W.M. Cole, eds., (W.B. Saunders, Philadelphia, PA)
    • EVERSON, T.C., and COLE, W.M. (1966). Spontaneous regression of malignant melanoma. In Spontaneous Regression of Cancer, T.C. Everson and W.M. Cole, eds., (W.B. Saunders, Philadelphia, PA), pp. 164-215.
    • (1966) Spontaneous Regression of Cancer , pp. 164-215
    • Everson, T.C.1    Cole, W.M.2
  • 23
    • 0025233918 scopus 로고
    • Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections
    • FAULDS, D., and HEEL, R.C. (1990). Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections. Drugs 39(4), 597-638.
    • (1990) Drugs , vol.39 , Issue.4 , pp. 597-638
    • Faulds, D.1    Heel, R.C.2
  • 25
    • 0027381621 scopus 로고
    • Chemotherapy and chemoimmunotherapy in disseminated malignant melanoma
    • GARBE, C. (1993). Chemotherapy and chemoimmunotherapy in disseminated malignant melanoma. Melanoma Res. 3(4), 291-9.
    • (1993) Melanoma Res. , vol.3 , Issue.4 , pp. 291-299
    • Garbe, C.1
  • 26
    • 0023837138 scopus 로고
    • The role of regional hyperthermic cytostatic perfusion in the treatment of extremity melanoma
    • GHUSSEN, F., KRUGER, I., GROTH, W., and STUTZER, H. (1988). The role of regional hyperthermic cytostatic perfusion in the treatment of extremity melanoma. Cancer 61(4), 654-9.
    • (1988) Cancer , vol.61 , Issue.4 , pp. 654-659
    • Ghussen, F.1    Kruger, I.2    Groth, W.3    Stutzer, H.4
  • 27
    • 0030138247 scopus 로고    scopus 로고
    • Potential salmon sperm origin of the E3 region insert of the adenovirus 5 d1309 mutant
    • GINGRAS, M.C., AREVALO, P., and AGUILAR-CORDOVA, E. (1996). Potential salmon sperm origin of the E3 region insert of the adenovirus 5 d1309 mutant. Cancer Gene Ther. 3(3), 151-4.
    • (1996) Cancer Gene Ther. , vol.3 , Issue.3 , pp. 151-154
    • Gingras, M.C.1    Arevalo, P.2    Aguilar-Cordova, E.3
  • 28
    • 0024372662 scopus 로고
    • The emerging epidemic of melanoma and squamous cell skin cancer
    • GLASS, A.G., and HOOVER, R.N. (1989). The emerging epidemic of melanoma and squamous cell skin cancer [see comments]. JAMA 262(15), 2097-100.
    • (1989) JAMA , vol.262 , Issue.15 , pp. 2097-2100
    • Glass, A.G.1    Hoover, R.N.2
  • 29
    • 0024409501 scopus 로고
    • GM-CSF with ganciclovir for the treatment of CMV retinitis in AIDS
    • GROSSBERG, H.S., BONNEM, E.M., and BUHLES, W.C., JR. (1989). GM-CSF with ganciclovir for the treatment of CMV retinitis in AIDS [letter]. N. Engl. J. Med. 320(23), 1560.
    • (1989) N. Engl. J. Med. , vol.320 , Issue.23 , pp. 1560
    • Grossberg, H.S.1    Bonnem, E.M.2    Buhles W.C., Jr.3
  • 31
    • 0030874410 scopus 로고    scopus 로고
    • Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome
    • [published erratum appears in N. Engl. J. Med. 1997 Oct 2;337(14):1019]
    • JACOBSON, M.A. (1997). Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome [published erratum appears in N. Engl. J. Med. 1997 Oct 2;337(14):1019]. N. Engl. J. Med. 337(2), 105-14.
    • (1997) N. Engl. J. Med. , vol.337 , Issue.2 , pp. 105-114
    • Jacobson, M.A.1
  • 32
    • 0028403237 scopus 로고
    • Viral vector systems for gene therapy
    • JOLLY, D. (1994). Viral vector systems for gene therapy. Cancer Gene Ther. 1(1), 51-64.
    • (1994) Cancer Gene Ther. , vol.1 , Issue.1 , pp. 51-64
    • Jolly, D.1
  • 33
    • 0028235166 scopus 로고
    • Retroviral transfer of herpes simplex thymidine kinase gene into glioma cells causes targeting of ganciclovir cytotoxic effect
    • KATO, K., YOSHIDA, J., MIZUNO, M., SUGITA, K., and EMI, N. (1994). Retroviral transfer of herpes simplex thymidine kinase gene into glioma cells causes targeting of ganciclovir cytotoxic effect. Neurol. Med. Chir. (Tokyo). 34(6), 339-44.
    • (1994) Neurol. Med. Chir. (Tokyo) , vol.34 , Issue.6 , pp. 339-344
    • Kato, K.1    Yoshida, J.2    Mizuno, M.3    Sugita, K.4    Emi, N.5
  • 34
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group Trial EST 1684
    • KIRKWOOD, J.M., STRAWDERMAN, M.H., ERNSTOFF, M.S., SMITH, T.J., BORDEN, E.C., and BLUM, R.H. (1996). Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684 [see comments]. J. Clin. Oncol. 14(1), 7-17.
    • (1996) J. Clin. Oncol. , vol.14 , Issue.1 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3    Smith, T.J.4    Borden, E.C.5    Blum, R.H.6
  • 36
    • 0031963294 scopus 로고    scopus 로고
    • Cancer statistics, 1998. CA: Cancer
    • LANDIS, S.H., MURRAY, T., BOLDEN, S., and WINGO, P. (1998). Cancer statistics, 1998. CA: Cancer. J. Clin. 48(1), 6-30.
    • (1998) J. Clin. , vol.48 , Issue.1 , pp. 6-30
    • Landis, S.H.1    Murray, T.2    Bolden, S.3    Wingo, P.4
  • 37
    • 0023633360 scopus 로고
    • Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus
    • LASKIN, O.L., CEDERBERG, D.M., MILLS, J., ERON, L.J., MILDVAN, D., and SPECTOR, S.A. (1987). Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus. Am. J. Med. 83(2), 201-7.
    • (1987) Am. J. Med. , vol.83 , Issue.2 , pp. 201-207
    • Laskin, O.L.1    Cederberg, D.M.2    Mills, J.3    Eron, L.J.4    Mildvan, D.5    Spector, S.A.6
  • 38
    • 0020573744 scopus 로고
    • Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro
    • MAR, E.C., CHENG, Y.C., and HUANG, E.S. (1983). Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro. Antimicrob. Agents Chemother. 24(4), 518-21.
    • (1983) Antimicrob. Agents Chemother. , vol.24 , Issue.4 , pp. 518-521
    • Mar, E.C.1    Cheng, Y.C.2    Huang, E.S.3
  • 39
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • MOOLTEN, F.L. (1986a). Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res. 46(10), 5276-81.
    • (1986) Cancer Res. , vol.46 , Issue.10 , pp. 5276-5281
    • Moolten, F.L.1
  • 40
    • 0025241769 scopus 로고
    • Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
    • MOOLTEN, F.L., and WELLS, J.M. (1990b). Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J. Natl. Cancer Inst. 82(4), 297-300.
    • (1990) J. Natl. Cancer Inst. , vol.82 , Issue.4 , pp. 297-300
    • Moolten, F.L.1    Wells, J.M.2
  • 41
    • 0026599586 scopus 로고
    • Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine : A negative selection system
    • MULLEN, C.A., KILSTRUP, M., and BLAESE, R.M. (1992). Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine : a negative selection system. Proc. Natl. Acad. Sci. USA 89(1), 33-7.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , Issue.1 , pp. 33-37
    • Mullen, C.A.1    Kilstrup, M.2    Blaese, R.M.3
  • 42
    • 0027343870 scopus 로고
    • Chemotherapy of malignant melanoma
    • L. Nathanson, ed., (Kluwer Academic Publishers, Boston)
    • NATHANSON, L., and JILANI, S. (1993). Chemotherapy of malignant melanoma. In Current Research and Clinical Management of Melanoma., L. Nathanson, ed., (Kluwer Academic Publishers, Boston), pp. 335-354.
    • (1993) Current Research and Clinical Management of Melanoma , pp. 335-354
    • Nathanson, L.1    Jilani, S.2
  • 43
    • 0030855528 scopus 로고    scopus 로고
    • Sensitivity and reproducibility in adenoviral infectious titer determination
    • NYBERG-HOFFMAN, C., SHABRAM, P., LI, W., GIROUX, D., and AGUILAR-CORDOVA, E. (1997). Sensitivity and reproducibility in adenoviral infectious titer determination. Nat. Med. 3(7), 808-11.
    • (1997) Nat. Med. , vol.3 , Issue.7 , pp. 808-811
    • Nyberg-Hoffman, C.1    Shabram, P.2    Li, W.3    Giroux, D.4    Aguilar-Cordova, E.5
  • 44
    • 0027548077 scopus 로고
    • Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir
    • OLDFIELD, E.H., RAM, Z., CULVER, K.W., BLAESE, R.M., DEVROOM, H.L., and ANDERSON, W.F. (1993). Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum. Gene Ther. 4(1), 39-69.
    • (1993) Hum. Gene Ther. , vol.4 , Issue.1 , pp. 39-69
    • Oldfield, E.H.1    Ram, Z.2    Culver, K.W.3    Blaese, R.M.4    Devroom, H.L.5
  • 47
    • 0023485229 scopus 로고
    • The rate of malignant melanoma in the United States: Are we making an impact?
    • RIGEL, D.S., KOPF, A.W., and FRIEDMAN, R.J. (1987). The rate of malignant melanoma in the United States: are we making an impact? J. Am. Acad. Dermatol. 17(6), 1050-3.
    • (1987) J. Am. Acad. Dermatol. , vol.17 , Issue.6 , pp. 1050-1053
    • Rigel, D.S.1    Kopf, A.W.2    Friedman, R.J.3
  • 48
    • 0027529476 scopus 로고
    • Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer
    • [published erratum appears in J. Natl. Cancer. Inst. 1993 Jul 7:85(13):1091]
    • ROSENBERG, S.A., LOTZE, M.T., YANG, J.C., TOPALIAN, S.L., CHANG, A.E., SCHWARTZENTRUBER, D.J., AEBERSOLD, P., LEITMAN, S., LINEHAN, W.M., SEIPP, C.A., and et al. (1993). Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer [published erratum appears in J. Natl. Cancer. Inst. 1993 Jul 7:85(13):1091]. J. Natl. Cancer Inst. 85(8), 622-32.
    • (1993) J. Natl. Cancer Inst. , vol.85 , Issue.8 , pp. 622-632
    • Rosenberg, S.A.1    Lotze, M.T.2    Yang, J.C.3    Topalian, S.L.4    Chang, A.E.5    Schwartzentruber, D.J.6    Aebersold, P.7    Leitman, S.8    Linehan, W.M.9    Seipp, C.A.10
  • 49
    • 0031025998 scopus 로고    scopus 로고
    • Gene therapy for cancer: What have we done and where are we going?
    • ROTH, J.A., and CRISTIANO, R.J., (1997). Gene therapy for cancer: what have we done and where are we going? J. Natl. Cancer. Inst. 89(1), 21-39.
    • (1997) J. Natl. Cancer. Inst. , vol.89 , Issue.1 , pp. 21-39
    • Roth, J.A.1    Cristiano, R.J.2
  • 50
    • 0028916763 scopus 로고
    • An estimate of the incidence of malignant melanoma in the United States. Based on a survey of members of the American Academy of Dermatology
    • SALOPEK, T.G., MARGHOOB, A.A., SLADE, J.M., RAO, B., RIGEL, D.S., KOPF, A.W., and BART, R.S. (1995). An estimate of the incidence of malignant melanoma in the United States. Based on a survey of members of the American Academy of Dermatology. Dermatol. Surg. 21(4), 301-5.
    • (1995) Dermatol. Surg. , vol.21 , Issue.4 , pp. 301-305
    • Salopek, T.G.1    Marghoob, A.A.2    Slade, J.M.3    Rao, B.4    Rigel, D.S.5    Kopf, A.W.6    Bart, R.S.7
  • 51
    • 0342899204 scopus 로고    scopus 로고
    • Herpes simplex thymidine-kinase (HSV-tk) mediated gene therapy is safe and active against locally recurrent prostate cancer after irradiation therapy
    • SCARDINO, P.T., ADLER, H.L., HERMAN, J.R., WOO, S.L.C., AGUILAR-CORDOVA, E., TIMME, T.L., and THOMPSON, T.C. (1998). Herpes simplex thymidine-kinase (HSV-tk) mediated gene therapy is safe and active against locally recurrent prostate cancer after irradiation therapy. Proc. Amer. Soc. Clin. Oncol. 17, 308a.
    • (1998) Proc. Amer. Soc. Clin. Oncol. , vol.17
    • Scardino, P.T.1    Adler, H.L.2    Herman, J.R.3    Woo, S.L.C.4    Aguilar-Cordova, E.5    Timme, T.L.6    Thompson, T.C.7
  • 55
    • 0001793010 scopus 로고    scopus 로고
    • Prognostic clinical and pathological features
    • C.M. Balch, A.N. Houghton, A.J. Sober, and S.-J. Soong, eds., (Quality Medical Publishing, St. Louis)
    • STADELMAN, W.K., RAPAPORT, D.P., SOONG, S.-J., REITGEN, D.S., BUZAID, A.C., and BLACH, C.M. (1998). Prognostic clinical and pathological features. In Cutaneous Melanoma, C.M. Balch, A.N. Houghton, A.J. Sober, and S.-J. Soong, eds., (Quality Medical Publishing, St. Louis), pp. 11-32.
    • (1998) Cutaneous Melanoma , pp. 11-32
    • Stadelman, W.K.1    Rapaport, D.P.2    Soong, S.-J.3    Reitgen, D.S.4    Buzaid, A.C.5    Blach, C.M.6
  • 56
    • 17344365922 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
    • STERMAN, D.H., TREAT, J., LITZKY, L.A., AMIN, K.M., COONROD, L., MOLNAR-KIMBER, K., RECIO, A., KNOX, L., WILSON, J.M., ALBELDA, S.M., and KAISER, L.R. (1998). Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum. Gene Ther. 9(7), 1083-92.
    • (1998) Hum. Gene Ther. , vol.9 , Issue.7 , pp. 1083-1092
    • Sterman, D.H.1    Treat, J.2    Litzky, L.A.3    Amin, K.M.4    Coonrod, L.5    Molnar-Kimber, K.6    Recio, A.7    Knox, L.8    Wilson, J.M.9    Albelda, S.M.10    Kaiser, L.R.11
  • 57
    • 0026445469 scopus 로고
    • Gene therapy of malignant brain tumors: A rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells
    • TAKAMIYA, Y., SHORT, M.P., EZZEDDINE, Z.D., MOOLTEN, F.L., BREAKEFIELD, X.O., and MARTUZA, R.L. (1992). Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type 1-thymidine kinase gene and wild type retrovirus kills other tumor cells. J. Neurosci. Res. 33(3), 493-503.
    • (1992) J. Neurosci. Res. , vol.33 , Issue.3 , pp. 493-503
    • Takamiya, Y.1    Short, M.P.2    Ezzeddine, Z.D.3    Moolten, F.L.4    Breakefield, X.O.5    Martuza, R.L.6
  • 58
    • 0028075655 scopus 로고
    • Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
    • VILE, R.G., NELSON, J.A., CASTLEDEN, S., CHONG, H., and HART, I.R. (1994). Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component. Cancer Res. 54(23), 6228-34.
    • (1994) Cancer Res. , vol.54 , Issue.23 , pp. 6228-6234
    • Vile, R.G.1    Nelson, J.A.2    Castleden, S.3    Chong, H.4    Hart, I.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.