Comparison between anthracyclines and rhodamine-123 accumulation in chronic lymphoid leukemia: Effect of cyclosporin A and verapamil

Tumor Biology

Volumn 19, Issue 1, 1997, Pages 41-51

  Maia, Raquel C ^a,b   Vasconcelos, Flávia C ^a   Harab, Ramza C ^a   Coelho, Arthur Moellman ^a   Dobbin, Jane A ^a   Rumjanek, Vivian M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Anthracyclines; Multidrug resistance; P glycoprotein; Rhodamine 123

Indexed keywords

ALKALINE PHOSPHATASE; ANTHRACYCLINE DERIVATIVE; CYCLOSPORIN A; DAUNORUBICIN; EPIRUBICIN; GLYCOPROTEIN P; IDARUBICIN; PHOSPHATASE; RHODAMINE 123; VERAPAMIL; VINCRISTINE;

ADULT; AGED; ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG ACCUMULATION; DRUG TRANSPORT; FEMALE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL;

EID: 0031469539     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000029973     Document Type: Article

References (38)

1. Catovsky D, Murphy RLW: Key issues in the treatment of chronic lymphocytic leukemia (CLL). Eur J Cancer 1995;31A:2146-2154.
2. Chabner BA, Bates SE, Fojo AT, Spolyar M, Wilson WH: Drug resistance in adult lymphomas. Semin Hematol 1994;31:70-87.
3. Sparrow RL, Hall FG, Firegar H, Van Der Weyden MB: Common expression of the multidrug resistance marker P-glycoprotein in B-cell chronic lymphocytic leukaemia and correlation with in vitro drug resistance. Leuk Res 1993;17:941-947.
4. Gottesman MM, Pastan I: The multidrug transporter, a double-edged sword. J Biol Chem 1988;263: 12163-12166.
5. Riordan JR, Deuchars K, Karner N, Alon N, Trend J, Ling V: Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature 1995;316:817-819.
6. Beck WT: The cell biology of multiple drug resistance. Biochem Pharmacol 1987;36:2879-2887.
7. Krishan A, Ganapathi R: Laser flow cytometric studies on intracellular fluorescence of anthracyclines. Cancer Res 1980;40:3895-3900.
8. Herweijer H, Sonneveld P, Baas F, Nooter K: Expression of mdr-1 and mdr-3 multidrug resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporin. J Natl Cancer Inst 1990;82:1133- 1140.
9. Neyfakh AA: Use of fluorescent dyes as molecular probes for the study of multidrug resistance. Exp Cell Res 1988;174:168-176.
10. Grulois I, Fardel O, Drenou B, Lamy T, Le Prisé PI, Fauchet R: Multidrug resistance in B-cell chronic lymphocytic leukemia. Acta Haematol 1995;94:78-83.
11. Ludescher C, Hilbe W, Eisterer W, Preuss E, Huber C, Gotwald M, Huffman J, Thaler J: Activity of P- glycoprotein in B-cell chronic lymphocytic leukemia determined by a flow cytometric assay. J Natl Cancer Inst 1993;85:1751-1758.
12. Wall DM, Sparrow R, Hu XF, Nadalin G, Zalcberg JR, Marschner IC, Van Der Weyden M, Parkin JD: Clinical application of a rapid, functional assay for multidrug resistance based on accumulation of the fluorescent dye, fluo 3. Eur J Cancer 1993;29A:1024-1027.
13. Wulf G, Kluding H, Ho AD, Doerner M, Daehner H, Manegold C, Hunstein W: Multidrug resistance phenotype in patients with chronic lymphocytic leukemia as detected by immunofluorescence (FACS) and Northern blot analysis. Leukemia Res 1994;18:475-484.
14. Sonneveld P, Nooter K, Burghous JT, Heweijer H, Adriaansen HJ, van Donguen JJ: High expression of the mdr 3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia. Blood 1992;79:1496- 1500.
15. Smit JJM, Schinkel AH, Oude Elferink RPJ, Groen AK, Wagenaar E, van Deemter L, Mol CAAM, Ottenhoff R, van der Lugt NMT, van Roon MA, van der Valk MA, Offerhaus GJA, Berns AJM, Borst P: Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 1993;75:451-462.
16. Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AMV, Deeley RG: Overexpression of a novel transporter gene in a multidrug resistant human lung cancer cell line. Science 1992;258:1650- 1654.
17. Higgins CF: ABC transporters from microorganisms to man. Annu Rev Cell Biol 1992;8:67-113.
18. Burger H, Nooter K, Zaman GJR, Sonneveld P, Van Wingerden KE, Oostrum RG, Stoter G: Expression of the multidrug resistance-associated protein (MRP) in acute and chronic leukemias. Leukemia 1994; 8:990-997.
19. Coley HM, Workman P, Twentyman PR: Retention of activity by selected anthracyclines in a multidrug-resistant human large-cell lung-carcinoma line without P-glycoprotein hyper-expression. Br J Cancer 1991;63:351-357.
20. Tusuruo T, Iida H, Ohkochi E, Tsukagoshi S, Sakurai Y: Establishment and properties of a vincristine-resistant human myelogenous leukemia K562. Jpn J Cancer (Gann) 1983; 74:751-758.
21. Maia RC, Wagner K, Cabral RH, Rumjanek VM: Heparin reverses rhodamine-123 extrusion by multidrug resistant cells. Cancer Lett 1996;106:101-108.
22. Maia RC, Silva EAC, Cabral RH, Lucena M, Pires V, Rumjanek VM: Sensitivity of vincristine-sensitive K562 and vincristine-resistant K562-Lucena 1 cells to anthracyclines and reversal of multidrug resistance. Braz J Med Biol Res 1996; 29:467-472.
23. Rumjanek VM, Lucena M, Campos MM, Marques-Silva VM, Maia RC: Multidrug resistance in leukemias: The problem and some approaches to its circumvention. Ciência Cultura 1994;46:63-69.
24. Cordell JL, Falini B, Erber WN, Abdulazig Z, Mac-Donald S, Pulford KAF, Stein H, Mason DDY: Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984;32:219-229.
25. Speth PAJ, Minderman HJ, Haanen C: Idarubicin vs daunorubicin: Preclinical and clinical pharmacokinetic studies. Semin Oncol 1989; 16(suppl 2):2-9.
26. Boiron JM, Belloc F, Montastruc M, Cony-Makhoul P, Dumain P, Marit G, Mahon F-X, Puntous M, Lopes F, Lacombe F, Reiffers J: Flow cytometric study of idarubicin and daunorubicin accumulation and the effect of verapamil in leukemic cell lines and fresh cells from patients with acute non-lymphoblastic leukemia. Leuk Res 1994;18:313-318.
27. Hargrave RM, Davey MW, Davey RA, Kidman AD: Development of drug resistance is reduced with idarubicin relative to other anthracyclines. Anti-Cancer Drugs 1995;6: 432-437.
28. Chen CJ, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM, Roninson IB: Internal duplication and homology with bacterial transport proteins in the mdr-1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 1986;47:381-389.
29. Van Der Blick AM, Kooiman PM, Schneider C, Borst P: Sequence of mdr3 cDNA encoding a human P- glycoprotein. Gene 1988;71:401- 411.
30. Nooter K, Sonneveld P, Janssen A, Oostrum R, Boersma T, Herwweijer H, Valerio D, Hagemeijer A, Baas F: Expression of the mdr3 gene in prolymphocytic leukemia: Association with cyclosporin A-induced increase in drug accumulation. Int J Cancer 1990;45:626-631.
31. Zaman GJR, Flens MJ, Van Leusden MR, Haas M, Mülder HS, Lankelma J, Pinedo HM, Scheper RJ, Baas F, Broxterman HJ, Borst P: The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc Natl Acad Sci USA 1994;91:8822- 8826.
32. Burger H, Nooter K, Sonneveld P, Van Wingerder KE, Zaman GJ, Stoter G: High expression of the multidrug resistance-associated protein (MRP) in chronic and prolymphocytic leukemia. Br J Haematol 1994;88:348-356.
33. Davey MW, Hargrave RM, Davey RA: Comparison of drug accumulation in P-glycoprotein-expressing and MRP-expressing human leukaemia cells. Leuk Res 1996;20: 657-664.
34. Feller N, Kuiper CM, Lankelma J, Ruhdal JK, Scheper RJ, Pinedo HM, Broxterman HJ: Functional detection of MDR1/P170 and MRP/P190 mediated multidrug resistance in tumor cells by flow cytometry. Br J Cancer 1995;72:543- 549.
35. Aftab DT, Yangg JM, Hait WN: Functional role of phosphorylation of the multidrug transporter by protein kinase C in multidrug-resistant MCF-7 cells. Oncol Res 1994;6:59- 70.
36. Bates SE, Lee JS, Dickstein B, Spolyaar M, Fojo AT: Differential modulation of P-glycoprotein transporter by protein kinase inhibition. Biochemistry 1993;32:9156-9164.
37. Weinstein RS, Kuszak JR, Jakate SM, Lebovitz MD, Klustens LF, Coon JS: ABO blood type predicts the cytolocalization of anti-P-glycoprotein monoclonal antibody reactivity in human colon and ureter. Hum Pathol 1990;21:949-958.
38. Beck J, Niethammer D, Geleker V: MDR1, MRP, topoisomerase II α/β, and cyclin A gene expression in acute and chronic leukemias. Leukemia 1996;10(suppl 3):S39-S45.