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Volumn 34, Issue 6, 1998, Pages 908-913

Efficacy of MGI 114 (6-hydroxymethylacylfulvene, HMAF) against the mdr1/gp170 metastatic MV522 lung carcinoma xenograft

Author keywords

6 hydroxymethylacylfulvene; Antitumour activity; Carcinoma; Gp170; HMAF; Mdr1; MGI 114; MV522; Non small cell lung cancer; NSC 683863; Xenograft

Indexed keywords

6 HYDROXYMETHYLACYLFULVENE; ANTINEOPLASTIC AGENT; DOXORUBICIN; MITOMYCIN C; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; UNCLASSIFIED DRUG; VINBLASTINE SULFATE;

EID: 0032077401     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00033-1     Document Type: Article
Times cited : (41)

References (31)
  • 2
    • 0030971388 scopus 로고    scopus 로고
    • The multimodality treatment of stage III A/B non-small cell lung cancer
    • Lee JD, Ginsberg RJ. The multimodality treatment of stage III A/B non-small cell lung cancer. Hematol Oncol Clin 1997,11, 279-301.
    • (1997) Hematol Oncol Clin , vol.11 , pp. 279-301
    • Lee, J.D.1    Ginsberg, R.J.2
  • 3
    • 0027210487 scopus 로고
    • Polychemotherapy in advanced non small cell lung cancer: A meta-analysis
    • Souquet PJ, Chauvin F, Boissel JP, et al. Polychemotherapy in advanced non small cell lung cancer: a meta-analysis. Lancet 1993, 342, 19-21.
    • (1993) Lancet , vol.342 , pp. 19-21
    • Souquet, P.J.1    Chauvin, F.2    Boissel, J.P.3
  • 4
    • 0025155530 scopus 로고
    • Treatment of small-cell lung cancer with an alternating chemotherapy regimen given at weekly intervals: A Southwest Oncology Group pilot study
    • Taylor CW, Crowley J, Williamson SK, et al. Treatment of small-cell lung cancer with an alternating chemotherapy regimen given at weekly intervals: a Southwest Oncology Group pilot study. 3 Clin Oncol 1990, 8, 1811-1817.
    • (1990) 3 Clin Oncol , vol.8 , pp. 1811-1817
    • Taylor, C.W.1    Crowley, J.2    Williamson, S.K.3
  • 6
    • 0026440636 scopus 로고
    • Chemotherapy of lung cancer
    • Ihde DC. Chemotherapy of lung cancer. New Engl J Med 1992, 27, 1434-1441.
    • (1992) New Engl J Med , vol.27 , pp. 1434-1441
    • Ihde, D.C.1
  • 8
    • 0025168447 scopus 로고
    • Preclinical evaluation of illudins as anti-cancer agents. Basis for selective cytotoxicity
    • Kelner MJ, McMorris TC, Taetle R. Preclinical evaluation of illudins as anti-cancer agents. Basis for selective cytotoxicity. J Natl Cancer Inst 1990, 82, 156-165.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 156-165
    • Kelner, M.J.1    McMorris, T.C.2    Taetle, R.3
  • 9
    • 0029142483 scopus 로고
    • In vitro and in vivo studies on the anticancer activity of dehydroilludin M
    • Kelner MJ, McMorris TC, Taetle R. In vitro and in vivo studies on the anticancer activity of dehydroilludin M. Anticancer Res 1995, 15, 873-878.
    • (1995) Anticancer Res , vol.15 , pp. 873-878
    • Kelner, M.J.1    McMorris, T.C.2    Taetle, R.3
  • 10
  • 11
    • 0028883899 scopus 로고
    • Efficacy of acylfulvene illudin analogs against a metastatic lung carcinoma MV522 nonresponsive to traditional anticancer agents
    • Kelner MJ, McMorris TC, Estes L, et al. Efficacy of acylfulvene illudin analogs against a metastatic lung carcinoma MV522 nonresponsive to traditional anticancer agents. Cancer Res 1995, 55, 4936-4940.
    • (1995) Cancer Res , vol.55 , pp. 4936-4940
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3
  • 12
    • 0029800935 scopus 로고    scopus 로고
    • Efficacy of HMAF (MGI 114) in the MV522 metastatic lung carcinoma model nonresponsive to traditional anticancer agents
    • Kelner MJ, McMorris TC, Estes L, Wang W, Samson KM, Taetle R. Efficacy of HMAF (MGI 114) in the MV522 metastatic lung carcinoma model nonresponsive to traditional anticancer agents. Invest New Drugs 1996, 141, 161-167.
    • (1996) Invest New Drugs , vol.141 , pp. 161-167
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3    Wang, W.4    Samson, K.M.5    Taetle, R.6
  • 13
    • 0031031009 scopus 로고    scopus 로고
    • Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S
    • MacDonald JR, Muscoplat CC, Dexter DL, et al. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S. Cancer Res 1997, 57, 279-283.
    • (1997) Cancer Res , vol.57 , pp. 279-283
    • MacDonald, J.R.1    Muscoplat, C.C.2    Dexter, D.L.3
  • 14
    • 0028168639 scopus 로고
    • Characterization of illudin S sensitivity in DNA repair deficient Chinese hamster cells: Unusually high sensitivity of ERCC2 and ERCC3 DNA helicase deficient mutants in comparison to other chemotherapeutic agents
    • Kelner MJ, McMorris TC, Estes L, et al. Characterization of illudin S sensitivity in DNA repair deficient Chinese hamster cells: unusually high sensitivity of ERCC2 and ERCC3 DNA helicase deficient mutants in comparison to other chemotherapeutic agents. Biochem Pharmacol 1994, 48, 403-409.
    • (1994) Biochem Pharmacol , vol.48 , pp. 403-409
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3
  • 15
    • 0024279163 scopus 로고
    • The multidrug transporter, a double-edged sword
    • Gottesman MM, Pastan I. The multidrug transporter, a double-edged sword. J Biol Chem 1988, 263, 12163-12166.
    • (1988) J Biol Chem , vol.263 , pp. 12163-12166
    • Gottesman, M.M.1    Pastan, I.2
  • 16
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumours
    • Simon SM, Schindler M. Cell biological mechanisms of multidrug resistance in tumours. Proc Natl Acad Sci USA 1994, 91, 3497-3504.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 17
    • 0002140454 scopus 로고
    • The multidrug-resistance gene (MDR1) represents a potential target for reversing drug resistance in human malignancies
    • Dalton W, Sikic BI. The multidrug-resistance gene (MDR1) represents a potential target for reversing drug resistance in human malignancies. J NIH Res 1994, 6, 54-58.
    • (1994) J NIH Res , vol.6 , pp. 54-58
    • Dalton, W.1    Sikic, B.I.2
  • 18
    • 0003009070 scopus 로고
    • Multidrug resistance is not an important factor in therapeutic outcome in human malignancies
    • Houghton PJ, Kaye SB. Multidrug resistance is not an important factor in therapeutic outcome in human malignancies. J NIH Res 1994, 6, 55-61.
    • (1994) J NIH Res , vol.6 , pp. 55-61
    • Houghton, P.J.1    Kaye, S.B.2
  • 19
    • 0028894303 scopus 로고
    • Multidrug-resistance modulation in metastatic breast cancer patients
    • Mross K. Multidrug-resistance modulation in metastatic breast cancer patients. J Clin Oncol 1995, 13, 303-304.
    • (1995) J Clin Oncol , vol.13 , pp. 303-304
    • Mross, K.1
  • 20
    • 0029059773 scopus 로고
    • Multidrug resistance is more than MDR1 activity
    • Preisler HD. Multidrug resistance is more than MDR1 activity. Leukemia Res 1995, 19, 429-431.
    • (1995) Leukemia Res , vol.19 , pp. 429-431
    • Preisler, H.D.1
  • 21
    • 0027459423 scopus 로고
    • MDR-1 gene expression, anthracycline retention, and cytotoxicity in human-tumor cells from refractory patients
    • Ramachandran C, Sauertegit A, Sridhar KS, Thuler RJ, Krishan A. MDR-1 gene expression, anthracycline retention, and cytotoxicity in human-tumor cells from refractory patients. Cancer Chemother Pharmacol 1993, 31, 431-441.
    • (1993) Cancer Chemother Pharmacol , vol.31 , pp. 431-441
    • Ramachandran, C.1    Sauertegit, A.2    Sridhar, K.S.3    Thuler, R.J.4    Krishan, A.5
  • 22
    • 0028983195 scopus 로고
    • Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents
    • Kelner MJ, McMorris TC, Estes L, et al. Nonresponsiveness of the metastatic human lung carcinoma MV522 xenograft to conventional anticancer agents. Anticancer Res 1995, 15, 867-872.
    • (1995) Anticancer Res , vol.15 , pp. 867-872
    • Kelner, M.J.1    McMorris, T.C.2    Estes, L.3
  • 23
    • 0025775062 scopus 로고
    • Feasibility of a high-flux anticancer drug screen using adiverse panel of cultured human cell lines
    • Monks A, Scuderio D, Skehan P, et al. Feasibility of a high-flux anticancer drug screen using adiverse panel of cultured human cell lines. J Natl Cancer Institute 1991, 83, 757-766.
    • (1991) J Natl Cancer Institute , vol.83 , pp. 757-766
    • Monks, A.1    Scuderio, D.2    Skehan, P.3
  • 24
    • 8244228308 scopus 로고
    • Fungal metabolites. the structures of the novel sesquiterpenes illudin-S and -M
    • McMorris TC, Anchel M. Fungal metabolites. The structures of the novel sesquiterpenes illudin-S and -M. J Am Chem Soc 1965, 87, 1594-1600.
    • (1965) J Am Chem Soc , vol.87 , pp. 1594-1600
    • McMorris, T.C.1    Anchel, M.2
  • 25
    • 0029834306 scopus 로고    scopus 로고
    • Hydroxymethylacylfulvene: An illudin derivative with superior antitumor properties
    • McMorris TC, Kelner MJ, Wang W, Yu J, Estes L, Taetle R. Hydroxymethylacylfulvene: an illudin derivative with superior antitumor properties. J Natural Products 1996, 59, 896-899.
    • (1996) J Natural Products , vol.59 , pp. 896-899
    • McMorris, T.C.1    Kelner, M.J.2    Wang, W.3    Yu, J.4    Estes, L.5    Taetle, R.6
  • 26
    • 0013508682 scopus 로고
    • A retrovirus carrying an mdr1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan I, Gottesman MM, Ueda K, Lovelace E, Rutherford AV, Willingham MC. A retrovirus carrying an mdr1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc Natl Acad Sci USA 1988, 85, 4486-4490.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutherford, A.V.5    Willingham, M.C.6
  • 27
    • 0023146915 scopus 로고
    • Use of nude mouse xenografts as preclinical drug screen: In vivo activity of established chemotherapeutic agents against melanomas and ovarian carcinoma xenografts
    • Taetle R, Rosen F, Abramson I, Beneditti J, Howell S. Use of nude mouse xenografts as preclinical drug screen: in vivo activity of established chemotherapeutic agents against melanomas and ovarian carcinoma xenografts. Cancer Treat Rep 1987, 71, 297-304.
    • (1987) Cancer Treat Rep , vol.71 , pp. 297-304
    • Taetle, R.1    Rosen, F.2    Abramson, I.3    Beneditti, J.4    Howell, S.5
  • 28
    • 0029916895 scopus 로고    scopus 로고
    • Effects of all-trans retinoic acid and antireceptor antibodies on growth and programmed cell death of human myeloma cells
    • Taetle R, Dos Santos B, Akamatsu K-I, Koishihara Y, Ohsug Y. Effects of all-trans retinoic acid and antireceptor antibodies on growth and programmed cell death of human myeloma cells. Clin Cancer Res 1996, 2, 253-259.
    • (1996) Clin Cancer Res , vol.2 , pp. 253-259
    • Taetle, R.1    Dos Santos, B.2    Akamatsu, K.-I.3    Koishihara, Y.4    Ohsug, Y.5
  • 30
    • 0029052483 scopus 로고
    • Efficient expression of functional human MDR1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells
    • Licht T, Aksentijevich I, Gottesman MM, Pastan I. Efficient expression of functional human MDR1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells. Blood 1995, 86, 111-121.
    • (1995) Blood , vol.86 , pp. 111-121
    • Licht, T.1    Aksentijevich, I.2    Gottesman, M.M.3    Pastan, I.4
  • 31
    • 0029913728 scopus 로고    scopus 로고
    • Bicistronic and two-gene retroviralectors for using MDR1 as a selectable marker and a therapeutic gene
    • Metz MZ, Matsumoto L, Wintera KA, Doroshow JH, Kane SE. Bicistronic and two-gene retroviralectors for using MDR1 as a selectable marker and a therapeutic gene. Virology 1996, 217, 230-241.
    • (1996) Virology , vol.217 , pp. 230-241
    • Metz, M.Z.1    Matsumoto, L.2    Wintera, K.A.3    Doroshow, J.H.4    Kane, S.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.