δ-, but not μ- and κ-, opioid receptor activation protects neocortical neurons from glutamate-induced excitotoxic injury

Brain Research

Volumn 885, Issue 2, 2000, Pages 143-153

  Zhang, Junhui ^a   Haddad, Gabriel G ^a   Xia, Ying ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

opioid receptors; Excitotoxicity; Glutamate; Hypoxia; Neurons; Protection

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; GLUTAMIC ACID; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALTRINDOLE; OPIATE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HYPOXIA; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PATHOGENESIS; PREGNANCY; PRIORITY JOURNAL; RAT; RECEPTOR ACTIVATION; SEIZURE;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; ANIMALS; CELLS, CULTURED; CYTOPROTECTION; EMBRYO; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, LEUCINE-2-ALANINE; EXCITATORY AMINO ACID AGONISTS; FEMALE; GLUTAMIC ACID; L-LACTATE DEHYDROGENASE; NALTREXONE; NARCOTIC ANTAGONISTS; NEOCORTEX; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU;

EID: 0034624288     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02906-1     Document Type: Article

References (60)

1. 2+) currents in rat sensory neurons
2. Alkaloid δ agonist BW 373U86 increases hypoxia tolerance
3. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
4. 5]-enkephalin)
5. Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity
6. Glutamate neurotoxicity and diseases of the nervous system
7. The role of glutamate neurotoxicity in hypoxia-ischemic neuronal death (Review)
8. Kappa opiate receptor multiplicity: evidence for two U50, 488-sensitive kappa 1 subtypes and a novel kappa 3 subtype
9. Kappa-opioid tolerance and dependence in cultures of dopaminergic midbrain neurons
10. Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line
11. Dextrorphan reduces infarct volume. Vascular injury, and brain edema after ischemic brain injury
12. Delta and kappa opiate receptors in primary astroglial cultures from rat cerebral cortex
13. Suppression of evoked potentials with continued ion transport during anoxia in turtle brain
14. +
15. Opioid-induced second window of cardioprotection potential role of mitochondrial K(ATP) channels
16. Dextromethorphan reduces neocortical ischemic neuronal damage in vivo
17. Dextrorphan and dextromethorphan attenuate hypoxic injury in neuronal culture
18. Hypoxic neuronal injury in vitro depends on extracellular glutamine
19. 2 deprivation induces a major depolarization in brain stem neurons in the adult but not in the neonatal rat
20. 2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury
21. 3H]PL017) to mu opioid receptors in rat brain
22. Laminar distribution of the multiple opioid receptors in the human cerebral cortex
23. 2+ transients by a μ-opioid receptor agonist in dorsal horn neurons
24. 2+ exchange in the rat brain during ontogeny
25. Opioids and pain
26. Protection of rat spinal cord from ischemia with dextrorphan and cyloheximide: effects on necrosis and apoptosis
27. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
28. Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain
29. Delta-Opioid receptor-mediated regulation of central dopaminergic neurons in the rat
30. Neuroprotective profile of lifarizine (RS-87476) in rat cerebrocortical neurons in culture
31. Role of endogenous opioid receptors in the acute adaptation to hypoxia
32. Delta-1 opioid receptor dependence of acute hypoxic adaptation
33. Delta-1 opioid agonist acutely increases hypoxic tolerance
34. Opioid receptors participate in ischemic preconditioning in rabbits (Abstract)
35. Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
36. + currents in magnocellular neurons of the supraoptic nucleus in rat
37. Hypoxia and brain development
38. Chondroitin sulfate proteoglycans protect cultured rat's cortical and hippocampal neurons from delayed cell death induced by excitatory amino acids
39. Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist
40. Application of the message-address concept in the design of highly potent and selective non-peptide δ opioid receptor antagonists
41. Design of peptidomimetic δ opioid receptor antagonists using the message-address concept
42. Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia
43. Glutamate and pathophysiology of hypoxic-ischemic brain damage
44. Excitotoxicity and the NMDA receptor
45. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart
46. 1- but not μ- or κ-opioid receptors
47. 1-opioid receptor agonist, reduces infarct size via activation of Gi/o protein and K(ATP) channels
48. Neuroanatomical patterns of the μ, δ, and κ opioid receptors of rat brain as determined by quantitative in vitro autoradiography
49. Time window for the contribution of the delta-opioid receptor to cardioprotection by ischemic preconditioning in the rat heart
50. Calcium and neuronal ageing (Review)
51. Turtle cortical neurons survive glutamate exposures that are lethal to mammalian neurons
52. Major differences in CNS sulfonylurea receptor distribution between the rat (newborn, adult) and turtle
53. Ontogeny and distribution of opioid receptors in the rat brainstem
54. Neuroanatomical distribution and binding properties of saxitoxin sites in the rat and turtle CNS
55. + channels: differential regulation in adult versus fetal rat brains
56. Major differences in δ-opioid receptor density and binding affinity between turtle and rat brains
57. Oxidative and glycolytic pathways in rat (newborn, adult) and turtle: Role in anoxia
58. Evidence for p53-mediated modulation of neuronal viability
59. 2+ stores in NG108-15 cells
60. Age-related mu-, delta- and kappa-opioid ligands in respiratory-related brain regions of piglets: effect of prenatal cocaine