Vaccines for Moraxella catarrhalis

Vaccine

Volumn 19, Issue SUPPL. 1, 2000, Pages

  McMichael, John C ^a  

^a PFIZER INC   (United States)

Author keywords

Moraxella (Branhamella) catarrhalis; Otitis media; Vaccine

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL VACCINE; BACTERIUM LIPOPOLYSACCHARIDE; BINDING PROTEIN; CATARRHALIS OUTER MEMBRANE PROTEIN B; E PORIN; HEMAGGLUTININ; LACTOFERRIN BINDING PROTEIN A; LACTOFERRIN BINDING PROTEIN B; MEMBRANE PROTEIN; PORIN; PROTEIN CD; TRANSFERRIN BINDING PROTEIN A; TRANSFERRIN BINDING PROTEIN B; UBIQUITOUS SURFACE PROTEIN A1; UBIQUITOUS SURFACE PROTEIN A2; UNCLASSIFIED DRUG;

ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ANTIGENICITY; ARTICLE; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIUM ADHERENCE; INFECTION PREVENTION; LUNG CLEARANCE; MORAXELLA CATARRHALIS; NONHUMAN; NUTRITION; OTITIS MEDIA; PATHOGENICITY; PRIORITY JOURNAL; SEROLOGY; VACCINE PRODUCTION;

EID: 0034623920     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00287-5     Document Type: Short Survey

References (53)

1. Branhamella catarrhalis: An organism gaining respect as a pathogen
2. Branhamella catarrhalis: Epidemiology, surface antigenic structure, and immune response
3. Moraxella (Branhamella) catarrhalis: Clinical, microbiological and immunological features in lower respiratory tract infections
4. Possible presence of a capsule in Branhamella catarrhalis
5. The presence of fimbriae (pili) in three species of Neisseria
6. The role of Branhamella catarrhalis in the 'Bloody Nose Syndrome' of Cynomologus macaques
7. Pulmonary clearance of Moraxella catarrhalis in an animal model
8. An aerosol challenge mouse model for Moraxella catarrhalis
9. Evaluation of purified UspA from Moraxella catarrhalis as a vaccine in a murine model after active immunization
10. Enhancement of pulmonary clearance of Moraxella (Branhamella) catarrhalis following immunization with outer membrane protein CD in a mouse model
11. Studies on haemagglutination and serum resistance status of strains of Moraxella catarrhalis isolated from the elderly
12. Correlation between hemagglutination and globotetraosylceramide binding by Branhamella catarrhalis
13. Phenotypic effect of isogenic uspA1 and uspA2 mutations on Moraxella catarrhalis strain O35E
14. Isolation and characterization of two proteins from Moraxella catarrhalis that bear a common epitope
15. The UspA1 protein and a second type of UspA2 protein mediate adherence of Moraxella catarrhalis to human epithelial cells in vitro
16. Characterization of the Moraxella catarrhalis UspA1 and UspA2 genes and their encoded products
17. Serum resistance in Haemophilus ducreyi requires outer membrane protein DsrA
18. A large, antigenically conserved protein on the surface of Moraxella catarrhalis is a target for protective antibodies
19. The levels and bactericidal capacity of antibodies directed against the UspA1 and UspA2 outer membrane proteins of Moraxella (Branhamella) catarrhalis in adults and children
20. Immune responses to specific antigens of Streptococcus pneumoniae and Moraxella catarrhalis in the respiratory tract
21. The major heat-modifiable outer membrane protein CD is highly conserved among strains of Branhamella catarrhalis
22. Middle ear mucin glycoprotein: Purification and interaction with nontypeable Haemophilus influenzae and Moraxella catarrhalis
23. Kinetics of the ascension of NTHi from the nasopharynx to the middle ear coincident with adenovirus-induced compromise in the chinchilla
24. Biochemical and immunological properties of lactoferrin binding proteins from Moraxella (Branhamella) catarrhalis
25. Analysis of the immunological responses to transferrin and lactoferrin receptor proteins from Moraxella catarrhalis
26. Transferrin receptors of Neisseria meningitidis: Promising candidates for a broadly cross-protective vaccine
27. Cloning and expression of the Moraxella catarrhalis lactoferrin receptor genes
28. Characterization of an outer membrane protein of Moraxella catarrhalis
29. Outer membrane protein B1, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin
30. Evaluation of a 74-kDa transferrin binding protein from Moraxella (Branhamella) catarrhalis as a vaccine candidate
31. The transferrin binding protein B of Moraxella catarrhalis elicits bactericidal antibodies and is a potential vaccine antigen
32. Construction and characterization of Moraxella catarrhalis mutants defective in expression of transferrin receptors
33. Expression of the CopB outer membrane protein by Moraxella catarrhalis is regulated by iron and affects iron acquisition from transferrin and lactoferrin
34. Growth of Moraxella catarrhalis with human transferrin and lactoferrin: Expression of iron-repressible proteins without siderophore production
35. A major outer membrane protein of Moraxella catarrhalis is a target for antibodies that enhance pulmonary clearance of the pathogen in an animal model
36. Mapping of a protective epitope of the CopB outer membrane protein of Moraxella catarrhalis
37. Molecular cloning and characterization of outer membrane protein E of Moraxella (Branhamella) catarrhalis
38. Sequence conservation and stability of outer membrane protein E of Moraxella catarrhalis recovered from the human respiratory tract
39. Serological typing of Branhamella catarrhalis strains on the basis of lipopolysaccharide antigens
40. Antibody response in rabbits to serotype-specific determinants in lipopolysaccharides from Moraxella catarrhalis
41. Synthesis and characterization of lipooligosaccharide-based conjugates as vaccine candidates for Moraxella (Branhamella) catarrhalis
42. An isolate of Moraxella catarrhalis undergoes variation in colony morphology and expression of UspA2
43. Control mechanism of the 200 kDa protein gene expression in Moraxella (Branhamella) catarrhalis
44. Differences in complement activation between complement-resistant and complement-sensitive Moraxella (Branhamella) catarrhalis strains occur at the level of membrane attack complex formation
45. Immunoglobulin G antibodies directed against protein III block killing of serum-resistant Neisseria gonorrhoeae by immune serum
46. Sequence of the structural gene (rmpM) for the class 4 outer membrane protein of Neisseria meningitidis, homology of the protein to gonococcal protein III and Escherichia coli OmpA, and construction of menigococcal strains that lack Class 4 proteins
47. A 200 kDa protein is associated with haemagglutinating isolates of Moraxella (Branhamella) catarrhalis
48. A protective epitope of Moraxella catarrhalis is encoded by two different genes
49. Characterization of an antigenically conserved heat-modifiable major outer membrane protein of Branhamella catarrhalis
50. The major outer membrane protein, CD, extracted from Moraxella (Branhamella) catarrhalis is a potential vaccine antigen that induces bactericidal antibodies
51. Antigenic characterization and analysis of the human immune response to outer membrane protein E of Branhamella catarrhalis