Polymyxin permeabilization as a tool to investigate cytotoxicity of therapeutic aromatic alkylators in DNA repair-deficient Escherichia coli strains

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 467, Issue 2, 2000, Pages 129-138

  Salmelin, Camilla ^a   Hovinen, Jari ^b   Vilpo, Juhani ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

3 Methyladenine DNA glycosylase; Alkylating agents; Chlorambucil; DNA repair; Escherichia coli; Mismatch repair; O6 Methylguanine DNA methyltransferase

Indexed keywords

3 METHYLADENINE; ALKYLATING AGENT; ANTINEOPLASTIC AGENT; AROMATIC COMPOUND; CHLORAMBUCIL; CHLORPHENACYL; CISPLATIN; CLADRIBINE; DNA GLYCOSYLTRANSFERASE; DOXORUBICIN; FLUDARABINE; IMMUNOSUPPRESSIVE AGENT; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITRONITROSOGUANIDINE; PHENYLACETIC ACID DERIVATIVE; POLYMYXIN B NONAPEPTIDE; UNCLASSIFIED DRUG; VINCRISTINE; VINCRISTINE SULFATE;

ARTICLE; BASE MISPAIRING; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; DNA CROSS LINKING; DNA REPAIR; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME DEFICIENCY; ESCHERICHIA COLI; EXCISION REPAIR; GENETIC ENGINEERING; MEMBRANE PERMEABILITY; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

ALKYLATING AGENTS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL MEMBRANE PERMEABILITY; CHLORAMBUCIL; CULTURE MEDIA; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; GENOTYPE; METHYLNITRONITROSOGUANIDINE; MUTAGENICITY TESTS; NITROGEN MUSTARD COMPOUNDS; POLYMYXINS; SENSITIVITY AND SPECIFICITY; ULTRAVIOLET RAYS;

EID: 0034621405     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(00)00026-7     Document Type: Article

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