A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases

Journal of Molecular Biology

Volumn 300, Issue 2, 2000, Pages 353-362

  Podobnik, Marjetka ^a,b   McInerney, Peter ^a   O'Donnell, Mike ^a   Kuriyan, John ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

DNA replication; Primase; RNA polymerase; Topoisomerase; TOPRIM

Indexed keywords

BACTERIAL ENZYME; DNA PRIMASE; DNA TOPOISOMERASE; RNA POLYMERASE;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DNA REPLICATION; DNA TEMPLATE; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

ESCHERICHIA COLI;

EID: 0034616957     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.3844     Document Type: Article

References (35)

1. Toprim - A conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
2. Structural similarities between topoisomerases that cleave one or both DNA strands
3. Structure and mechanism of DNA topoisomerase
4. Crystallography and NMR system: A new software suite for macromolecular structure determination
5. The CCP4 suite: Programs for protein crystallography
6. Identification of activesite residues in Escherichia coli DNA topoisomerase I
7. Identification of the primase active site of the herpes simplex virus type 1 helicase-primase
8. Performance evalu ation of amino acid substitution matrices
9. Protein structure comparison by alignment of distance matrices
10. Organization and evolution of bacterial and bacteriophage primase-helicase systems
11. Improved methods for building protein models in electron density maps and the location of errors in these models
12. Structure of the RNA polymerase domain of E. coli primase
13. Not your average density
14. PROCHECK: A program to check the stereochemical quality of protein structures
15. Did DNA replication evolve twice independently?
16. Three-dimensional structure of the 67 K N-terminal fragment of E. coli DNA topoisomerase I
17. A multienzyme system for priming the replication of phiX174 viral DNA
18. Studies of the functional topography of the catalytic center of Escherichia coli primase
19. Protein folding and association: Insights from the interracial and thermodynamic properties of hydrocarbons
20. Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11
21. Processing of X-ray diffraction data collected in oscillation mode
22. Structure of the zinc-binding domain of Bacillus stearothermophilus DNA primase
23. Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinase
24. A mechanism for all polymerases
25. A common sequence motif, -E-G-Y-A-T-A-, identified within the primase domains of plasmid-encoded I- and P-type DNA primases and the alpha protein of the Escherichia coli satellite phage P4
26. Difference refinement: Obtaining differences between two related structures
27. The CLUSTAL-X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
28. The interaction between helicase and primase sets the replication fork clock
29. Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork
30. Magnesium acetate induces a conformational change in Escherichia coli primase
31. The Haemophilus influenzae dnaG sequence and conserved bacterial primase motifs
32. DNA topoisomerases
33. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 Å resolution
34. Site-directed mutagenesis of conserved aspartates, glutamates and arginines in the active site region of Escherichia coli DNA topoisomerase I