Direct measurement of hole transport dynamics in DNA

Nature

Volumn 406, Issue 6791, 2000, Pages 51-53

  Lewis, Frederick D ^a   Liu, Xiaoyang ^a   Liu, Jianqin ^a   Miller, Scott E ^a   Hayes, Ryan T ^a   Wasielewski, Michael R ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA DAMAGE; ELECTRON TRANSPORT; ELECTRONICS; MOLECULAR DYNAMICS; PHOTOCHEMISTRY; PRIORITY JOURNAL;

BASE PAIRING; DNA; ELECTRONS; GUANINE; NUCLEIC ACID CONFORMATION; PHOTOCHEMISTRY; SPECTRUM ANALYSIS; STILBENES;

EID: 0034612513     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35017524     Document Type: Article

References (22)

1. Becker, D. & Sevilla, M. D. Chemical consequences of radiation damage in DNA. Adv. Radiat. Biol. 17, 121-180 (1993).
2. Armitage, B. Photocleavage of nucleic acids. Chem. Rev. 98, 1171-1200 (1998).
3. Langenbacher, T. et al. Substrate and temperature dependence of DNA photolyase repair activity examined with ultrafast spectroscopy. J. Am. Chem. Soc. 119, 10532-10536 (1998).
4. Ratner, M. A. & Jortner, J. in Molecular Electronics (eds Jortner, J. & Ratner, M.) 5-72 (Blackwell, Oxford, 1997).
5. Anderson, R. F. & Wright, G. A. Energetics and rate of electron transfer from base radical anions to electron-affinic intercalators in aqueous solution. Phys. Chem. Chem. Phys. 1, 4827-4831 (1999).
6. Lewis, F. D. et al. Distance-dependent electron transfer in DNA hairpins. Science 277, 673-676 (1997).
7. Lewis, F. D. et al. Dynamics of photoinduced charge separation and charge recombination in synthetic DNA hairpins with stilbenedicarboxamide linkers. J. Am. Chem. Soc. 122, 2889-2902 (2000).
8. Harriman, A. Electron tunneling in DNA. Angew. Chem. Int. Edn Engl. 38, 945-949 (1999).
9. Fukui, K. et al. Distance dependence of electron transfer in acridine-intercalated DNA. J. Photochem. Photobiol. B 50, 18-27 (1999).
10. Núñez, M. E., Hall, D. B. & Barton, J. A. Long-range oxidative damage to DNA: effects of distance and sequence. Chem. Biol. 6, 85-97 (1999).
11. Meggers, E., Michel-Beyerle, M. E. & Giese, B. Sequence dependent long range hole transport in DNA. J. Am. Chem. Soc. 120, 12950-12955 (1998).
12. Giese, B. et al. On the mechanism of long-range electron transfer through DNA. Angew. Chem. Int. Edn Engl. 38, 996-998 (1999).
13. Henderson, P. T., Jones, D., Hampikian, G., Kan, Y. & Schuster, G. Long-distance charge transport in duplex DNA: the phonon-assisted polaron-like hopping mechanism. Proc. Natl Acad. Sci. USA 96, 8353-8358 (1999).
14. Priyadarshy, S., Risser, S. M. & Beratan, D. N. DNA is not a molecular wire: protein-like electron-transfer predicted for an extended II-electron system. J. Phys. Chem. 100, 17678-17682 (1996).
15. Jortner, J., Bixon, M., Langenbacher, T. & Michel-Beyerle, M. E. Charge transfer and transport in DNA. Proc. Natl Acad. Sci. USA 95, 12759-12765 (1998).
16. Bixon, M. et al. Long-range charge hopping in DNA. Proc. Natl Acad. Sci. USA 96, 11713-11716 (1999).
17. Berlin, Y. A., Burin, A. L. & Ratner, M. On the long-range charge transfer in DNA. J. Phys. Chem. 104, 443-445 (2000).
18. Letsinger, R. L. & Wu, T. Use of a stilbenedicarboxamide bridge in stabilizing, monitoring, and photchemically altering folded conformations of oligonucleotides. J. Am. Chem. Soc. 117, 7323-7328 (1995).
19. Lewis, F. D. et al. Structure and photoinduced electron transfer in exceptionally stable synthetic DNA hairpins with stilbenediether linkers. J. Am. Chem. Soc. 121, 9905-9906 (1999).
20. Lewis, F. D., Liu, X., Miller, S. E. & Wasielewski, M. R. Electronic interactions between π-stacked DNA base pairs and diphenylacetylene-4,4′-dicarboxamide in hairpin DNA. J. Am. Chem. Soc. 121, 9746-9747 (1999).
21. Burrows, C. J. & Muller, J. G. Oxidative nucleobase modifications leading to strand scission. Chem. Rev. 98, 1109-1151 (1998).
22. Steenken, S. Electron transfer in DNA? Competition by ultra-fast proton-transfer? Biol. Chem. 378, 1293-1297 (1997).