The dopamine D2/D3 antagonist DS121 potentiates the effect of cocaine on locomotion and reduces tolerance in cocaine tolerant rats

Behavioural Brain Research

Volumn 116, Issue 2, 2000, Pages 169-175

  Ellinwood, Everett H ^a   King, George R ^b   Davidson, Colin ^a   Lee, Tong H ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Autoreceptor; Cocaine; Dopamine; DS121; Locomotor activity; Tolerance

Indexed keywords

3 (1 PROPYL 3 PIPERIDINYL)BENZONITRILE; COCAINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DOPAMINE AUTORECEPTOR; 3 (3 CYANOPHENYL) N N PROPYLPIPERIDINE; 3-(3-CYANOPHENYL)-N-N-PROPYLPIPERIDINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DRD3 PROTEIN, RAT; NITRILE; PIPERIDINE DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; DRUG TOLERANCE; LOCOMOTION; MALE; NONHUMAN; OSMOTIC MINIPUMP; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY; WAKEFULNESS; ANIMAL; COCAINE DEPENDENCE; DOSE RESPONSE; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; LOCOMOTION; MALE; NITRILES; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3;

EID: 0034610185     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(00)00270-9     Document Type: Article

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