Repeated intravenous cocaine administration: Locomotor activity and dopamine D2/D3 receptors

Synapse

Volumn 23, Issue 3, 1996, Pages 152-163

  Wallace, David R ^a   Mactutus, Charles F ^b,c,d   Booze, Rosemarie M ^a,c  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b Department of Pharmaceutical Sciences College of Pharmacy   (United States)

^c Dept of Nutrition and Food Science   (United States)

^d Tobacco and Health Research Institute   (United States)

Author keywords

Nucleus accumbens; Psychostimulant; Sensitization; Striatum; Vascular access port

Indexed keywords

COCAINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ABUSE; DRUG RECEPTOR BINDING; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; REINFORCEMENT;

ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; COCAINE; DOPAMINE UPTAKE INHIBITORS; DRUG TOLERANCE; INJECTIONS, INTRAVENOUS; MALE; MOTOR ACTIVITY; NARCOTICS; NEOSTRIATUM; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3;

EID: 0029901688     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(199607)23:3<152::AID-SYN4>3.0.CO;2-7     Document Type: Article

References (86)

1. Ackerman, J.M., and White, F.J. (1990) A10 somatodendritic dopamine autoreceptor sensitivity following withdrawal from repeated cocaine treatment. Neurosci. Lett., 117:181-187.
2. Akimoto, K., Hamamura, T., and Otsuki, S. (1989) Subchronic cocaine treatment enhances cocaine-induced dopamine efflux, studied by in vivo intracerebral dialysis. Brain Res., 490: 339-344.
3. Antelman, S.M., and Chiodo, L.A. (1981) Dopamine autoreceptor subsensitivity: A mechanism common to the treatment of depression and induction of amphetamine psychosis. Biol. Psychiatr., 16:717-727.
4. Bennett, J.P., and Yamamura, H.I. (1985) Neurotransmitter, hormone or drug receptor binding methods. In: Neurotransmitter Receptor Binding. H.I. Yamamura, S.J. Enna, and M.J. Kuhar, eds. Raven Press, New York, pp. 61-89.
5. 125I]-Iodosulpride. Synapse, 19:1-13.
6. Booze, R.M., Lehner, A.F., Wallace, D.R., Welch, M.A., and Mactutus, C.F. (1996) Dose-response cocaine pharmacokinetics and metabolite profile following intravenous administration and arterial sampling in unanesthetized freely moving male rats. Neurotoxicol. Teratology, submitted.
7. Borison, R.L., Hitri, A., Klawans, H.L., and Diamond, B.I. (1979) A new model for schizophrenia: Behavioral and receptor binding studies. In: Catecholamines: Basic and Clinical Frontiers. E. Usdin, I.J. Kopin, and J. Barchas, eds. Pergamon Press, New York, pp. 719-722.
8. Boundy, V.A., Luedtke, R.R., Gallitano, A.L., Smith, J.E., Filtz, T.M., Kallen, R.G., and Molinoff, R.B. (1993) Expression and characterization of the rat D3 dopamine receptor: Pharmacological properties and development of antibodies. J. Pharmacol. Exp. Ther., 264:1002-1011.
9. 2 receptor mRNA. Brain Res., 564:203-219.
10. Caine, S.B., and Koob, G.F. (1993) Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science, 260:1814-1816.
11. Cass, W.A., Gerhardt, G.A., Gillespie, K., Curella, P., Mayfield, R.D., and Zahniser, N.R. (1993) Reduced clearance of exogenous dopamine in rat nucleus accumbens, but not in dorsal striatum, following cocaine challenge in rats withdrawn from repeated cocaine administration. J. Neurochem., 61:273-283.
12. 3 receptor ligand. Eur. J. Pharmacol., 249:R9-R10.
13. DeVane, C.L., Simpkins, J.W., Miller, R.L., and Braun, S.B. (1989) Tissue distribution of cocaine in the pregnant rat. Life Sci., 45:1271-1276.
14. 3 receptor in the rat brain. Neuroscience, 65:731-745.
15. Dow-Edwards, D. (1990) Fetal and maternal cocaine levels peak rapidly following intragastric administration in the rat. J. Subst. Abuse, 2:427-437.
16. Downs, A.W., and Eddy, N.B. (1932) The effect of repeated doses of cocaine on the rat. J. Pharmacol. Exp. Ther., 46:199-200.
17. Dunwiddie, T.V. (1988) Mechanisms of cocaine abuse and toxicity : An overview. In: Mechanisms of Cocaine Abuse and Toxicity, NIDA Research Monograph 88, D. Clouet, K. Asghar, and R. Brown, eds. U.S. Government Printing Office, Washington, pp. 336-353.
18. Emmett-Oglesby, M.W. (1995) Sensitization and tolerance to motivational and subjective effects of psychostimulants. In: The Neurobiology of Cocaine: Cellular and Molecular Mechanisms, R.P. Hammer, Jr., ed. CRC Press, Boca Raton, pp. 31-47.
19. Evans, S.M., Cone, E.J., and Henningfield, J.E. (1995) Rapid arterial kinetics of intravenous and smoked cocaine: Relationship to subjective and cardiovascular effects. In: Natl. Inst. Drug Abuse Res. Monogr. Ser. 153: Problems of Drug Dependence 1994: Proceedings of the 56th Annual Scientific Meeting, L.S. Harris, ed. U.S. Government Printing Office, Washington, D.C., p. 223.
20. Evenden, J.L., and Ryan, C.N. (1988) Behavioral responses to psychomotor stimulant drugs: Localization in the central nervous system. Pharmacol. Ther., 36:151-172.
21. Fallon, J.H., and Moore, R.Y. (1979) Catecholamine innervation of the basal forebrain. IV. Topography of the dopamine projection to the basal forebrain and the neostriatum. J. Comp. Neurol., 180:545-580.
22. Fitzgerald, L.W., and Nestler, E.J. (1995) Cocaine regulation of signal transduction pathways. In: The Neurobiology of Cocaine: Cellular and Molecular Mechanisms, R.P. Hammer, Jr., ed. CRC Press, Boca Raton, pp. 225-246.
23. 3 receptors in rat brain. Eur. J. Pharmacol., 211:189-194.
24. 3 agonist, 7-OH-DPAT, reduces dopamine release in the nucleus accumbens and electrical self-stimulation to the ventral tegmentum. Brain res., 681:1-7.
25. Godbout, R., Mantz, J., Pirot, S., Glowinski, J., and Thierry, A.M. (1991) Inhibitory influence of the mesocortical dopaminergic neurons on their target cells: Electrophysiological and pharmacological characterization. J. Pharmacol. Exp. Ther., 258:728-733.
26. Goeders, N.B. (1990) The effects of chronic cocaine administration on brain neurotransmitter receptors. Drug Dev. Res., 20:349-357.
27. Goeders, N.E., and Kuhar, M.J. (1987) Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens. Alcohol Drug Res., 7:207-216.
28. Henry, D.J., and White, F.J. (1991) Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens. J. Pharmacol. Exp. Ther., 258:882-890.
29. Henry, D.J., Greene, M.A., and White, F.J. (1989) Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: Repeated administration. J. Pharmacol. Exp. Ther., 251:833-839.
30. 3H]7-hydroxy-N,N-di-n-propyl-2-aminotetralin. Brain Res., 648:222-228.
31. Imperato, A., Angelucci, L., Casolini, P., Zocchi, A., and Puglisi-Allegra, S. (1992) Repeated stressful experiences differently affect limbic dopamine release during and following stress. Brain Res., 577:194-199.
32. Kalivas, PW. (1995) Neural basis of behavioral sensitization to cocaine. In: The Neurobiology of Cocaine: Cellular and Molecular Mechanisms, R.P. Hammer, Jr., ed. CRC Press, Boca Raton, pp. 81-98.
33. Kalivas, P.W., and Duffy, P. (1990) Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens. Synapse, 5:48-58.
34. Kalivas, P.W., and Stewart, J. (1991) Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Rev., 16:223-244.
35. Kalivas, P.W., and Weber, B. (1988) Amphetamine injection into the ventral mesencephalon sensitizes rats to peripheral amphetamine and cocaine. J. Pharmacol. Exp. Ther., 245:1095-1102.
36. Kalivas, P.W., Duffy, P., DuMars, L.A., and Skinner, C. (1988) Neurochemical and behavioral effects of acute and daily cocaine. J. Pharmacol. Exp. Ther., 245:1095-1102.
37. Keefe, K.A., and Gerfen, C.R. (1995) D1-D2 dopamine receptor synergy in striatum: Effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression. Neuroscience, 66:903-913.
38. Keppel, G. (1973) Design and analysis: A researcher's handbook. Prentice-Hall, Englewood Cliffs, New Jersey.
39. Kling-Petersen, T., and Svensson, K. (1989) A new computer program for the control of in vivo brain self stimulation: Application to the effects of a new class of central stimulants. Proc. Soc. Neurosci., 15:1134.
40. 125I]trans-7-OH-PIPAT-A. Eur. J. Pharmacol., 235:165-166.
41. 2 synergism are unrelated to changes in striatal receptor density. Synapse, 12:14-26.
42. Landwehrmeyer, B., Mengod, G., and Palacios, J.M. (1993) Differential visualization of dopamine D2 and D3 receptor sites in rat brain: A comparative study using in situ hybridization histochemistry and ligand binding autoradiography. Eur. J. Neurosci., 5:145-153.
43. 3 autoreceptors inhibits firing of ventral tegmental dopaminergic neurones in vivo. Eur. J. Pharmacol., 275:R7-R9.
44. 3 receptors. Synapse, 14:90-95.
45. 3H]hydroxy-N,N-di-n-propyl-2-aminotetralin. Proc. Natl. Acad. Sci. USA, 89:8155-8159.
46. 3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons. Proc. Natl. Acad. Sci. USA, 92:1719-1723.
47. Mactutus, C.F., Herman, A.S., and Booze, R.M. (1994) Chronic intravenous model for studies of drug (ab)use in the pregnant and/or grouphoused rat: An initial study with cocaine. Neurotoxicol. Teratol., 16:183-191.
48. 3 receptors. Eur. J. Pharmacol., 249:R5-R6.
49. Mulder, T.B.A., de Vries, J.B., Dijkstra, D., Wiechers, J.W., Gröl, C.J., and Horn, A.S. (1987) Further in vitro and in vivo studies with the putative presynaptic dopamine agonist, N,N-dipropyl-7-hydroxy-2-aminotetralin. Naunyn-Schmied Arch. Pharmacol., 336:494-501.
50. 125I]epidepride. Eur. J. Pharmacol., 227:443-445.
51. ou in discrete regions of rat brain. J. Neurochem., 55:1079-1082.
52. Nestler, E.J. (1994) Molecular neurobiology of drug addiction. Neuropsychopharmacology, 11:77-97.
53. Nisenbaum, L.K., Zigmond, M.J., Sved, A.F., and Abercrombie, E.D. (1991) Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor. J. Neurosci., 11:1478-1484.
54. Orona, R.A., Mayfield, R.D., Cline, E.J., and Zahniser, N.R. (1994) Repeated intravenous cocaine administration to rats produces behavioral sensitization without changing brain cocaine levels. Neurosci. Lett., 167:121-124.
55. Peris, J., Boyson, S.J., Cass, W.A., Curella, P., Dwoskin, L.P., Larson, G., Lin, L.-H., Yasuda, R.P., and Zahniser, N.R. (1990) Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. J. Pharmacol. Exp. Ther., 253:38-44.
56. Persico, A.M., Schindler, C.W., Zaczek, R., Brannock, M.T., and Uhl, G.R. (1995) Brain transcription factor gene expression, neurotrasmitter levels, and novelty response behaviors: Alterations during rat amphetamine withdrawal and following chronic injection stress. Synapse, 19:212-227.
57. Perugini, M., and Vezina, P. (1994) Amphetamine administered to the ventral tegmental area sensitizes rats to the locomotor effects of nucleus accumbens amphetamine. J. Pharmacol. Exp. Ther., 270:690-696.
58. Pettit, H.O., Pan, H.-T., Parsons, L.H., and Justice, J.B., Jr. (1990) Extracellular concentrations of cocaine and dopamine are enhanced during chronic administration. J. Neurochem., 55:798-804.
59. Post, R.M. (1980) Intermittent versus continuous stimulation: Effect of time interval on the development of sensitization or tolerance. Life Sci., 26:1275-1282.
60. Post, R.M., and Contel, N.R. (1983) Human and animals studies of cocaine: Implications for development of behavioral pathology. In: Stimulants: Neurochemical, Behavioral and Clinical Perspectives, I. Creese, ed. Raven Press, New York, pp. 169-203.
61. Ritz, M.C., Lamb, R.J., Goldberg, S.R., and Kuhar, M.J. (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science, 237:1219-1223.
62. 3 receptors and σ sites in the bovine caudate nucleus. Eur. J. Pharmacol., 242:R1-R2.
63. 2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain. Proc. Natl. Acad. Sci. USA, 86:10156-10160.
64. o proteins in nucleus accumbens reduces both cocaine and heroin reinforcement. J. Neurosci., 14:6239-6247.
65. 3) as a target for neuroleptics. Nature, 347:146-151.
66. 2 receptor. Eur. J. Pharmacol., 225:331-337.
67. Sorg, B.A., and Ulibarri, C. (1995) Application of a protein synthesis inhibitor into the ventral tegmental area, but not the nucleus accumbens, prevents behavioral sensitization to cocaine. Synapse, 20:217-224.
68. Spear, L.P., Frambes, N.A., and Kirstein, C.L. (1989) Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following chronic subcutaneous administration of cocaine during gestation in rats. Psychopharmacology, 97:427-431.
69. Staley, J.K., Basile, M., Ouyang, Q., and Mash, D.C. (1994) Characterization of the D3 receptor in the human brain: regulation by cocaine abuse. Soc. Neurosci. Abstr., 20:221.
70. Stellar, J.R., and Corbett, D. (1989) Regional neuroleptic microinjections indicate a role for the nucleus accumbens in lateral hypothalamic stimulation reward. Brain Res., 477:126-143.
71. 1. Nature, 350:614-619.
72. Taylor, D., Ho, B.T., and Fagan, J.D. (1979) Increased dopamine receptor binding in rat brain by repeated cocaine injection. Commun. Psychopharmacol., 3:137-142.
73. Unterwald, E.M., Ho, A., Rubenfeld, J.M., andKreek, M.J. (1994) Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration. J. Pharmacol. Exp. Ther., 270:1387-1397.
74. 4 receptor with high affinity for the antipsychotic clozapine. Nature, 350:610-614.
75. Vezina, P., and Stewart, J. (1993) Amphetamine injected into the ventral tegmental area sensitizes the nucleus accumbens dopaminergic response to systemic amphetamine: An in vivo microdialysis study in the rat. Brain Res., 605:332-337.
76. 3H]-(±)-7-OH-DPAT and carbetapentane. J. Neurochem., 64:700-710.
77. Waters, N., Lofberg, L., Haadmsa-Svensson, S., Svensson, K., Sonesson, C., and Carlsson, A. (1994) Differential effects of dopamine D2 and D3 receptor antagonists in regard to dopamine release, in vivo receptor displacement and behaviour. J. Neural. Transm., 98:39-55.
78. White, F.J., and Wang, R.Y. (1984) Pharmacological characterization of dopamine autoreceptors in the rat ventral tegmental area: Microinotophoretic studies. J. Pharmacol. Exp. Ther., 231:275-283.
79. Wise, R.A. (1984) Neural mechanisms of the reinforcing action of cocaine. In: Pharmacology, Effects and Treatment of Abuse, National Institute on Drug Abuse Research Monograph No. 50., U.S. Government Printing Office, Washington, DC pp. 153-161.
80. Winer, B.J. (1971) Statistical principles in experimental design. McGraw-Hill, New York.
81. Wise, R.A., and Rompre, P.-P. (1989) Brain dopamine and reward. Annu. Rev. Psychol., 40:191-225.
82. Wolf, M.E., White, F.J., Nassar, R., Brooderson, R.J., and Khansa, M.R. (1993) Differential development of autoreceptor subsensitivity and enhanced dopamine release during amphetamine sensitization. J. Pharmacol. Exp. Ther., 264:249-255.
83. Zahniser, N.R., and Peris, J. (1992) Neurochemical mechansims of cocaine-induced sensitization. In: Cocaine: Pharmacology, Physiology, and Clinical Strategies. J.M. Lakoski, M.P. Galloway, and F.J. White, eds. CRC Press, Boca Raton, pp. 229-260.
84. Zahniser, N.R., Peris, J., Curella, P., Dwoskin, L.P., O'Keefe, L., and Boyson, S.J. (1988a) Repeated cocaine administration results in supersensitive nigrostriatal D-2 dopamine autoreceptors. In: Pharmacology and Functional Regulation of Dopaminergic Neurons. P.M. Beart, G. Woodruff and D.M. Jackson, eds. Macmillan Press, London, pp. 168-174.
85. Zahniser, N.R., Peris, J., Dwoskin, L.P., Curella, P., and Yasuda, R.P. (1988b) Sensitization to cocaine in the nigrostriatal dopamine system. In: National Institute on Drug Abuse Res. Monogr. Ser. 88: Mechanisms of Cocaine Abuse and Toxicity. D. Clouet, K. Asghar, and R. Brown, eds. U.S. Government Printing Office, Washington, D.C., pp. 55-77.
86. Zeigler, S., Lipton, J., Toga, A., and Ellison, G. (1991) Continuous cocaine administration produces persisting changes in brain neurochemistry and behavior. Brain Res., 555:27-35.