Altered activity of midbrain dopamine neurons following 7-day withdrawal from chronic cocaine abuse is normalized by D2 receptor stimulation during the early withdrawal phase

Neuropsychopharmacology

Volumn 21, Issue 1, 1999, Pages 127-136

  Lee, Tong H ^a   Gao, Wei Ying ^a   Davidson, Colin ^a   Ellinwood, Everett H ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bursting; Cocaine; D2 receptor; Dopamine; Single unit; Substantia nigra; Ventral tegmental area

Indexed keywords

APOMORPHINE; COCAINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 2 RECEPTOR; ECOPIPAM; QUINPIROLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DRUG WITHDRAWAL; INJECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SUBCUTANEOUS DRUG ADMINISTRATION; SUBSTANTIA NIGRA; SUPERSENSITIVITY; VENTRAL TEGMENTUM;

ANIMALS; APOMORPHINE; BENZAZEPINES; COCAINE-RELATED DISORDERS; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; ELECTROPHYSIOLOGY; MALE; MESENCEPHALON; NEURONS; QUINPIROLE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANTIA NIGRA; VENTRAL TEGMENTAL AREA;

EID: 0033020945     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00011-1     Document Type: Article

References (50)

1. Ackerman J.M., White F.J. Decreased activity of rat A10 dopamine neurons following withdrawal from repeated cocaine. Eur J Pharmacol. 218:1992;171-173.
2. Bunney B.S., Aghajanian G.K., Roth R.H. Comparison of effects of L-DOPA, amphetamine and apomorphine on firing rate of rat dopaminergic neurons. Nature. 245:1973;123-125.
3. Bunney B.S., Grace A.A. Acute and chronic haloperidol treatment. Comparison of effects on nigral dopaminergic cell activity Life Sci. 23:1978;1715-1727.
4. Cameron D.L., Williams J.T. Dopamine D1 receptors facilitate transmitter release. Nature. 366:1993;344-347.
5. Charlety P.J., Grenhoff J., Chergui K., De la Chapelle B., Buda M., Svensson T.H., Chouvet G. Burst firing of mesencephalic dopamine neurons is inhibited by somatodendritic application of kynurenate. Acta Phys Scand. 142:1991;105-112.
6. Chiodo L.A., Bunney B.S. Typical and atypical neuroleptics. Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons J Neurosci. 3:1983;1607-1619.
7. Dai M., Tepper J.M. Do silent dopaminergic neurons exist in rat substantia nigra in vivo? Neuroscience. 85:1998;1089-1099.
8. Ellinwood E.H. Jr., Lee T.H. Effect of continuous systematic infusion of d-amphetamine on the sensitivity of nigral dopamine cells to apomorphine inhibition of firing rate. Brain Res. 273:1983;379-383.
9. Gallager D.W., Pert A., Bunney W.E. Jr. Haloperidol-induced presynaptic dopamine supersensitivity is blocked by chronic lithium. Nature. 273:1978;309-312.
10. Gao W.Y., Lee T.H., King G.R., Ellinwood E.H. Alterations in baseline activity and quinpirole sensitivity in putative dopamine neurons in the substantia nigra and ventral tegmental area after withdrawal from cocaine pretreatment. Neuropsychopharmacology. 18:1998;222-232.
11. Gariano R.F., Groves P.M. Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices. Brain Res. 462:1988;194-198.
12. Gawin F.H., Ellinwood E.H. Jr. Cocaine and other stimulants. Actions, abuse and treatments N Engl J Med. 318:1988;1173-1182.
13. Gawin F.H., Khalsa H., Ellinwood E.H. Jr. Stimulants. Galanter M., Kleber H.D. Textbook of Substance Abuse. 1994;111-139 D.C., American Psychiatric Press, Washington.
14. Giannini A.J., Folts D.J., Feather J.N., Sullivan B.S. Bromocriptine and amantadine in cocaine detoxification. Psychiatry Res. 29:1989;11-16.
15. Gold M.S., Miller S., Jonas J.N. Cocaine (and crack). Neurobiology Lowinson J.H., Ruiz P., Millman R.B., Langrod J.G. Substance Abuse. A Comprehensive Textbook:1992;222-235 Williams and Wilkins, Baltimore, MD.
16. Gonon F.G. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience. 24:1988;19-28.
17. Grace A.A., Bunney B.S. The control of firing pattern in nigra dopamine neurons. Burst firing J Neurosci. 4:1984;2877-2890.
18. Henry D.J., Greene M.A., White F.J. Electrophysiological effect of cocaine in the mesoaccumbens dopamine system. Repeated administration J Pharmacol Exp Ther. 251:1989;833-839.
19. Inada T., Polk K., Purser C., Hume A., Hoskins B., Ho I.K., Rockhold R.W. Behavioral and neurochemical effects of continuous infusion of cocaine in rats. Neuropharmacology. 31:1992;701-708.
20. Jeziorski M., White F.J. Dopamine agonists at repeated "autoreceptor selective" doses. Effects upon the sensitivity of A10 dopamine neurons Synapse. 4:1989;267-280.
21. Joyner C., King G.R., Lee T.H., Ellinwood E.H. Jr. A technique for the continuous infusion of high doses of cocaine by osmotic minipump. Pharmacol Biochem Behav. 44:1993;971-973.
22. Kalivas P.W. Neural basis of behavioral sensitization to cocaine. Hammer R.P. Jr. The Neurobiology of Cocaine. Cellular and Molecular Mechanisms:1995;81-98 CRC Press, Boca Raton, FL.
23. Kalivas P.W., Duffy P. Repeated cocaine administration alters extracellular glutamate in the ventral tegmental area. J Neurochem. 70:1998;1497-1502.
24. Kamata K., Rebec G.V. Nigral dopaminergic neurons. Differential sensitivity to apomorphine following long-term treatment with low and high doses of amphetamine Brain Res. 321:1984;147-150.
25. Kilbey M.M., Ellinwood E.H. Jr. Administration of stimulant drugs. Response modification Ellinwood E.H. Jr., Kilbey M.M. Advances in Behavioral Biology. Cocaine and Other Stimulants:1977;409-429 Plenum Press, New York.
26. King G.R., Joyner C., Lee T.H., Kuhn C., Ellinwood E.H. Jr. Intermittent and continuous cocaine administration. Residual behavioral states during withdrawal Pharmacol Biochem Behav. 43:1992;243-248.
27. Kleber H.D. Pharmacology, current and potential for the treatment of cocaine dependence. Clin Neuropharmacol. 18[Suppl 1]:1995;96-s109.
28. Kramer J.C., Fischman V.S., Littlefield D.C. Amphetamine abuse. Pattern and effects of high doses taken intravenously JAMA. 201:1967;305.
29. Lau C.E., Imam A., Fang M., Falk J.L. Acute effects of cocaine on spontaneous and discriminative motor functions. Relation to route of administration and pharmacokinetics J Pharmacol Exper Ther. 257:1991;444-456.
30. Lee T.H., Ellinwood E.H. Jr. Time-dependent changes in the sensitivity of dopamine neurons to low doses of apomorphine following amphetamine infusion. Brain Res. 483:1989;17-29.
31. Lee T.H., Ellinwood E.H., Zhang H. In vitro extracellular recording from nigra dopamine neurons following continuous d-amphetamine infusion. Eur J Pharmacol. 232:1993;125-129.
32. Lee T.H., Gao W.-Y., Ellinwood E.H. Differential effects of SCH 23390 on the apomorphine subsensitivity in the substantia nigra and ventral tegmental area 1 day following withdrawal from continuous or intermittent cocaine pretreatment. Brain Res. 744:1997;293-301.
33. Lee T.H., Gee K.R., Ellinwood E.H., Seidler F.J. Altered cocaine potency in the nucleus accumbens following 7 day withdrawal from intermittent but not continuous treatment. Voltammetric assessment of dopamine uptake in the rat Psychopharmacology. 137:1998;303-310.
34. Mendrek A., Blaha C.D., Phillips A.G. Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule. Psychopharmacology. 135:1998;416-422.
35. Mereu G., Hu X.-T., Wang R.Y., Westfall T.C., Gessa G.L. Failure of subchronic lisuride to modify A10 dopamine autoreceptor's sensitivity. Brain Res. 408:1987;210-214.
36. Nickolson V.J. Detailed analysis of the effects of apomorphine and d-amphetamine on spontaneous locomotor behaviour in rats as measured in a TV-based, automated open-field system. Eur J Pharm. 72:1981;45-56.
37. Overton P.G., Clark D. Burst firing in midbrain dopaminergic neurons. Brain Res Rev. 25:1997;312-334.
38. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed:1986;Academic Press, San Diego.
39. Pitts D.K., Freeman A.S., Kelland M.D., Chiodo L.A. Repeated amphetamine, reduced dopamine neuronal responsiveness to apomorphine but not quinpirole. Eur J Pharmacol. 162:1989;167-171.
40. Pitts D.K., Kelland M.D., Freeman A.S., Chiodo L.A. Repeated amphetamine administration. Role of forebrain in reduced responsiveness of nigrostriatal dopamine neurons to dopamine agonists J Pharmacol Exp Ther. 264:1993;616-621.
41. Post R.M., Contel N.R. Human and animal studies of cocaine. Implications for development of behavioral pathology Creese I. Stimulants. Neurochemical, Behavioral, and Clinical Perspectives:1983;169-203 Raven Press, New York.
42. Post R.M., Rose H. Increasing effects of repetitive cocaine administration in the rat. Nature. 260:1976;731-732.
43. Reith M.E.A., Benuck M., Lajtha A. Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice. J Pharmacol Exp Ther. 243:1987;281-287.
44. Robinson T.E., Berridge K.C. The neural basis of drug craving. An incentive-sensitization theory of addiction Brain Res Rev. 18:1993;247-291.
45. Self D.W., Barnhart W.J., Lehman D.A., Nestler E.J. Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science. 271:1996;1586-1589.
46. Skirboll L.R., Grace A.A., Bunney B.S. Dopamine auto- and postsynaptic receptors. Electrophysiological evidence for differential sensitivity to dopamine agonists Science. 206:1979;80-82.
47. Svensson T.H., Tung C.-S. Local cooling of prefrontal cortex induces pacemaker-like firing of dopamine neurons in rat ventral tegmental area in vivo. Acta Physiol Scand. 136:1989;135-136.
48. Weiss F., Parsons L.H., Markou A. Neurochemistry of cocaine withdrawal. Hammer R.P. Jr. The Neurobiology of Cocaine. Cellular and Molecular Mechanisms:1995;163-181 CRC Press, Boca Raton, FL.
49. White F.J., Hu X.-T., Henry D.J., Zhang X.-F. Neurophysiological alterations in the mesocorticolimbic dopamine system with repeated cocaine administration. Hammer R.P. Jr. The Neurobiology of Cocaine. Cellular and Molecular Mechanisms:1995;99-119 CRC Press, Boca Raton, FL.
50. Zhang H., Lee T.H., Ellinwood E.H. Jr. The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine. Brain Res. 594:1992;315-318.