Increase of the single-channel conductance of KvLQT1 potassium channels induced by the association with minK

Pflugers Archiv European Journal of Physiology

Volumn 437, Issue 1, 1998, Pages 172-174

  Pusch, Michael ^a  

^a CNR   (Italy)

Author keywords

IsK; Long QT syndrome; Noise analysis

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ARTICLE; HEART MUSCLE CONDUCTION DISTURBANCE; LONG QT SYNDROME; MEMBRANE CHANNEL; NONHUMAN; OOCYTE; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; ELECTRIC CONDUCTIVITY; FEMALE; HUMANS; OOCYTES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; RECOMBINANT PROTEINS; TRANSFECTION; XENOPUS;

EID: 0032435120     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050765     Document Type: Article

References (8)

1. Barhanin J, Lesage F, Guillemare E, Fink M, Lazdunski M, Romey G (1996) K(V)LQT1 and IsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384:78-80
2. Pusch M, Steinmeyer K, Jentsch TJ (1994) Low single channel conductance of the major skeletal muscle chloride channel, CIC-1. Biophys J 66:149-152
3. Pusch M, Magrassi R, Wollnik B, Conti F (1998) Activation and inactivation of homomeric KvLQT1 potassium channels. Biophys J 75:785-792
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5. Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT (1996) Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel. Nature 384:80-83
6. Sesti F, Goldstein AN (1998) IKs channels: minK/KvLQT1 heteromultimers have a larger unitary conductance than homomeric KvLQT1 channels (abstract). Biophys J 74:A346
7. + channel (minK) subunits. J Physiol (Lond) 510:37-45
8. Yang Y, Sigworth FJ (1998) The conductance of KvLQT1 channels (abstract). Biophys J 74:A19