Are Alzheimer's disease, hypertension, and cerebrocapillary damage related?

Neurobiology of Aging

Volumn 21, Issue 2, 2000, Pages 235-243

  Farkas, Eszter ^a   De Vos, Rob A I ^b   Steur, Ernst N H Jansen ^b   Luiten, Paul G M ^a  

^a Grad Sch Behav Cogn N   (Netherlands)

^b MEDISCH SPECTRUM TWENTE   (Netherlands)

Author keywords

Alzheimer's disease; Carotid occlusion; Cerebral capillaries; Cerebral hypoperfusion; Chronic hypertension

Indexed keywords

ALZHEIMER DISEASE; ANIMAL MODEL; BRAIN BLOOD FLOW; BRAIN CAPILLARY; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; CHRONIC DISEASE; COGNITIVE DEFECT; CONFERENCE PAPER; DEGENERATION; DEMENTIA; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; HYPERTENSION; MICROVASCULATURE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; ULTRASTRUCTURE; VASCULAR DISEASE;

AGED; ALZHEIMER DISEASE; ANIMALS; CAPILLARIES; CEREBROVASCULAR CIRCULATION; HUMANS; HYPERTENSION; MIDDLE AGED; RATS;

EID: 0034603411     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(00)00122-6     Document Type: Conference Paper

References (56)

1. Arendash G.W., Su G.C., Crawford F.C., Bjugstad K.B., Mullan M. Intravascular beta-amyloid infusion increases blood pressure implications for a vasoactive role of beta-amyloid in the pathogenesis of Alzheimer's disease . Neurosci Lett. 268:1999;17-20.
2. Buée L., Hof P.R., Delacourte A. Brain microvascular changes in Alzheimer's disease and other dementias. Ann NY Acad Sci. 826:1997;7-24.
3. Claudio L. Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients. Acta Neuroptahol. 91:1996;6-14.
4. Claus J.J., Walstra G.J., Hijdra A., Van Royen E.A., Verbeeten B. Jr, van Gool W.A. Measurement of temporal regional cerebral pefusion with single-photon emission tomography predicts rate of decline in language function and survival in early Alzheimer's disease. Eur J Nucl Med. 26:(3):1999;265-271.
5. Croughwell N.D., Newman M.F., Blumenthal J.A., et al. Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass. Ann Thorac Surg. 58:1994;1702-1708.
6. De Jong G.I., Farkas E., Stienstra C.M., et al. Cerebral hypoperfusion yields capillary damage in hippocampus CA1 that correlated to spatial memory impairment. Neurosci. 91:(1):1999;203-210.
7. de la Torre J.C., Fortin T., Park G.A.S., et al. Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats. Brain Res. 582:1992;186-195.
8. de la Torre J.C., Mussivand T. Can disturbed brain microcirculation cause Alzheimer's disease? Neurol Res. 15:1993;146-153.
9. de la Torre J.C., Cada A., Nelson N., Davis G., Sutherland R.J., Gonzalez-Lima F. Reduced cytochrome oxidase and memory dysfunction after chronic brain ischemia in aged rats. Neurosci Lett. 233:1997;165-168.
10. de la Torre J.C. Critical threshold cerebral hypoperfusion causes Alzheimer's disease? Acta Neuropathol. 98:1999;1-8.
11. DeKosky S.T., Shih W.J., Schmitt F.A., Coupal J., Kirkpatrick C. Assessing utility of single photon emission computed tomography (SPECT) scan in Alzheimer disease correlation with cognitive severity . Alzheimer Dis Assoc Disord. 4:(1):1990;14-23.
12. Dickinson C.J. Cerebral oxidative metabolism in hypertension. Clin Sci. 91:1996;539-550.
13. Eberling J.L., Jagust W.J., Reed B.R., Baker M.G. Reduced temporal lobe blood flow in Alzheimer's disease. Neurobiol Aging. 13:1992;483-491.
14. Elias M.F., Wolf P.A., D'Agostino R.B., Cobb J., White L.R. Untreated blood pressure level is inversely related to cognitive functioning the Framingham Study . Am J Epidemiol. 138:1993;353-364.
15. Farkas E., De Jong G.I., De Vos R.A.I., Jansen Steur E.N.H., Luiten P.G.M. Cerebral microvascular breakdown in Alzheimer's disease and in experimental cerebral hypoperfusion. Iqbal K., Swaab D.F., Winblad B., Wisniewski H.M. Alzheimer's disease and related disorders. 1999;165-170 John Wiley & Sons Ltd, New York.
16. Farkas E, De Jong GI, De Vos RAI, Jansen Steur ENH, Luiten PGM. Pathological features of cerebral cortical capillaries are doubled in Alzheimer's disease and Parkinson's disease. Submitted to Acta Neuropathol. In press, 2000.
17. Farkas E, De Jong GI, Apró E, De Vos RAI, Jansen Steur ENH, Luiten PGM. Similar ultrastructural breakdown of cerebrocortical capillaries in Alzheimer's disease, Parkinson's disease and experimental hypertension. What is the functional link? Ann NY Acad Sci, in press, 2000.
18. Forette F., Rigaud A.S., Morin M., Gisselbrecht M., Bert P. Assessing vascular dementia. Neth J Med. 47:(4):1995;185-194.
19. Forette F., Seux M.L., Staessen, et al. Prevention of dementia in randomized double-blind placebo-controlled Systolic Hypertension in Europe (Sys-Eur) trial. Lancet. 352:(9137):1998;1347-1351.
20. Fukuyama H., Ogawa M., Yamaguchi H., et al. Altered cerebral energy metabolism in Alzheimer's disease a PET study . J Nucl Med. 35:(1):1994;1-6.
21. Fujii K., Sadoshima S., Okada Y., Yao H., Kuwabara Y., Ichiya Y., Fujishima M. Cerebral blood flow and metabolism in normotensive and hypertensive patients with transient neurologic deficits. Stroke. 21:(2):1990;283-290.
22. Fujishima M., Ibayashi S., Fujii K., Mori S. Cerebral blood flow and brain function in hypertension. Hypertens Res. 18:(2):1995;111-117.
23. Fujishima M., Tsuchihashi T. Hypertension and dementia. Clin Exp Hypertension. 1999;21(5&6):927-35
24. Furlan A.J., Sila C.A., Chimowitz M.I., Jones S.C. Neurologic complications related to cardiac surgery. Neurol Clin. 10:(1):1992;145-166.
25. Gunaydin B., Babacan A. Cerebral hypoperfusion after cardiac surgery and anesthetic strategies a comparative study with high dose fentanyl and barbiturate anesthesia . Ann Thorac Cardiovasc Surg. 4:(1):1998;12-17.
26. Herbert R., Brayne C. Epidemiology of vascular dementia. Neuroepidemiology. 14:(5):1995;240-257.
27. Harik S.I. Changes in the glucose transporter of brain capillaries. Can J Physiol Pharmacol. 70:(suppl):1992;S113-S117.
28. Horwood N., Davies D.C. Immunolabeling of hippocampal microvessel glucose transporter protein is reduced in Alzheimer's disease. Virchows Arch. 425:(1):1994;69-72.
29. Imran M.B., Kawashima R., Awata S., et al. Tc-99m HMPAO SPECT in the evaluation of Alzheimer's disease correlation between neuropsychiatric evaluation and CBF images . J Neurol Neurosurg Psychiatry. 66:(2):1999;228-232.
30. Kalaria R.N. Cerebral vessels in aging and Alzheimer's disease. Pharmacol Ther. 72:(3):1996;193-214.
31. Katsuta T. Decreased local cerebral blood flow in young and aged spontaneously hypertensive rats. Fukuoka Igaku Zasshi. 88:(3):1997;65-74.
32. Launer L.J., Masaki K., Petrovitch H., Foley D., Havlik R.J. The association between midlife blood pressure levels and late-life cognitive function. The Honolulu-Asia Aging Study JAMA. 274:1995;1846-1851.
33. Lis C.G., Gaviria M. Vascular dementia, hypertension, and the brain. Neurol Res. 19:(5):1997;471-480.
34. 2+ channel blockade in aging normotensive and hypertensive rat strains. Ann NY Acad Sci. 747:1994;431-451.
35. Mooradian A.D., Chung H.C., Shah G.N. GLUT-1 expression in the cerebra of patients with Alzheimer's disease. Neurobiol Aging. 18:(5):1997;469-474.
36. Nagata K., Buchan R.J., Yokoyama E., et al. Misery perfusion with preserved vascular reactivity in Alzheimer's disease. Ann NY Acad Sci. 826:1997;272-281.
37. Nakane H., Ibayashi S., Fujii K., Irie K., Sadoshima S., Fujishima M. Cerebral blood flow and metabolism in hypertensive patients with cerebral infarction. Angiology. 46:(9):1995;801-810.
38. Ni J.W., Ohta H., Matsumoto K., Wanatabe H. Progressive cognitive impairment after chronic cerebral hypoperfusion induced by permanent occlusion of bilateral carotid arteries in rats. Brain Res. 653:1994;231-236.
39. Nobili F., Rodriguez G., Marenco S., et al. Regional cerebral blood flow in chronic hypertension. A correlative study. Stroke. 24:(8):1993;1148-1153.
40. O'Brien J.T., Eagger S., Syed G.M., Sahakian B.J., Levy R. A study of regional cerebral blood flow and cognitive performance in Alzheimer's disease. J Neuro Neurosur Psych. 55:1992;1182-1187.
41. Ohnishi T., Hoshi H., Nagamachi S., Jinnouchi S., Flores L.G. II, Futami S., Watanabe K. High-resolution SPECT to assess hippocampal perfusion in neuropsychiatric diseases. J Nucl Med. 36:1995;1163-1169.
42. Ohta H., Nishikawa H., Kimura H., Anayama H., Miyamoto M. Chronic cerebral hypoperfusion by permanent internal carotid ligation produces learning impairment without brain damage in rats. Neuroscience. 79:(4):1997;1039-1050.
43. Pantoni L, Garcia JH. Cerebral ischemia and cognitive impairment in the elderly. Facts and research in gerontology. Stroke 1996;(suppl.):171-82.
44. Pappas B.A., de la Torre J.C., Davidson C.M., Keyes M.T., Fortin T. Chronic reduction of cerebral blood flow in the adult rat late-emerging CA1 cell loss and memory dysfunction . Brain Res. 708:1996;50-58.
45. Pappas B.A., Davidson C.M., Bennett S.A., de la Torre J.C., Fortin T., Tenniswood M.P. Chronic ischemia memory impairment and neural pathology in the rat . Ann NY Acad Sci. 826:1997;498-501.
46. Pavics L., Grunwald F., Reichmann K., et al. Regional cerebral blood flow single-photon emission tomography with 99 mTc-HMPAO and the acetazolamide test in the evaluation of vascular and Alzheimer's dementia. Eur J Nucl Med. 26:(3):1999;239-245.
47. Perlmutter L.S., Chui H.C. Microangiopathy, the vascular basement membrane and Alzheimer's Disease. Brain Res Bull. 24:1990;677-686.
48. Skoog I., Lernfelt B., Landahl S., et al. A 15-year longitudinal study on blood pressure and dementia. Lancet. 347:1996;1141-1145.
49. Skoog I. The relationship between blood pressure and dementia a review . Biomed Pharmacother. 51:1997;367-375.
50. Sparks D.L., Scheff S.W., Liu H., Landers T.M., Coyne C.M., Hunsaker J.C. III. Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension. J Neurol Sci. 131:1995;162-169.
51. Stump DA, Rogers AT, Hammon JW, Newman SP. Cerebral emboli and cognitive outcome after cardiac surgery. J Cardiothorac Vasc Anesth 1996;10(1):113-8; quiz 118-9.
52. Thomas T., Thomas G., McLendon C., Sutton T., Mullan M. beta-Amyloid mediated vasoactivity and vascular endothelial damage. Nature. 380:(6570):1996;168-171.
53. Tohgi H., Yonezawa H., Takahasi S., et al. Cerebral blood flow and oxygen metabolism in senile dementia of Alzheimer's type and vascular dementia with deep white matter changes. Neuroradiology. 40:(3):1998;131-137.
54. Tsuchiya M., Sako K., Yura S., Yonemasu Y. Cerebral blood flow and histopathological changes after permanent bilateral carotid artery ligation in Wistar rats. Exp Brain Res. 89:(1):1992;87-92.
55. Van Kooten F., Bots M.L., Breteler M.M., et al. The Dutch vascular factors in dementia study rationale and design . J Neurol. 245:(1):1998;32-39.
56. Wyss J.M., Fisk G., van Groen T. Impaired learning and memory in mature spontaneously hypertensive rats. Brain Res. 592:1992;135-140.