Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus

Journal of Biological Chemistry

Volumn 275, Issue 5, 2000, Pages 3065-3074

  Fernández Lozano, M José ^a   Remsing, Lily L ^b   Quirós, Luis M ^a   Braña, Alfredo F ^a   Fernández, Ernestina ^a   Sánchez, César ^a   Méndez, Carmen ^a   Rohr, Jürgen ^b   Salas, José A ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; METHYLTRANSFERASE; MITHRAMYCIN; PLASMID DNA; POLYKETIDE;

ACTINOBACTERIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOSYNTHESIS; DNA SEQUENCE; DRUG STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STREPTOMYCES;

AMINO ACID SEQUENCE; ANTIBIOTICS, ANTINEOPLASTIC; BACTERIAL PROTEINS; BASE SEQUENCE; CLONING, MOLECULAR; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; PLICAMYCIN; STREPTOMYCES; SUBSTRATE SPECIFICITY;

ACTINOBACTERIA (CLASS); PROKARYOTA; SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES; STREPTOMYCES ARGILLACEUS; STREPTOMYCES LIVIDANS; TRITIUM;

EID: 0034603167     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.5.3065     Document Type: Article

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