Stability-activity relationships of a family of G-tetrad forming oligonucleotides as potent HIV inhibitors. A basis for anti-HIV drug design

Journal of Biological Chemistry

Volumn 275, Issue 5, 2000, Pages 3421-3430

  Jing, Naijie ^a   De Clercq, Erik ^b   Rando, Robert F ^c   Pallansch, Luke ^d   Lackman Smith, Carol ^d   Lee, Sandy ^a   Hogan, Michael E ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c BioChem Pharma   (Canada)

^d SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; T 30695; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY; VIRUS INHIBITION; VIRUS REPLICATION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTI-HIV AGENTS; DRUG DESIGN; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; OLIGONUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0034603156     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.5.3421     Document Type: Article

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