The novel heteromeric bivalent ligand SB9 potently antagonizes P2Y1 receptor-mediated responses

Journal of the Autonomic Nervous System

Volumn 81, Issue 1-3, 2000, Pages 171-177

  Lambrecht, Günter ^a   Ganso, Matthias ^a   Bäumert, Hans G ^b   Spatz Kümbel, Gerhard ^b   Hildebrandt, Caren ^a   Braun, Kirsten ^a   Mutschler, Ernst ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Bivalent ligand; Ileum (guinea pig); P2 receptor antagonist; PPADS (pyridoxal 5' phosphate 6 phenylazo 2',4' disulfonate); SB9 (6 (4,6,8 trisulfo 1 naphthyl)iminocarbonyl 1,3 (4 methylphenylene)iminocarbonyl 1,3 phenylene azo pyridoxal 5' phosphate); Suramin; Vas deferens (rat)

Indexed keywords

6 [(4,6,8 TRISULFO 1 NAPHTHYL)IMINOCARBONYL 1,3 (4 METHYLPHENYLENE)IMINOCARBONYL 1,3 PHENYLENE AZO]; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL 5'PHOSPHATE; SURAMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVOUS SYSTEM; DRUG EFFECT; GUINEA PIG; ILEUM; LIGAND BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VAS DEFERENS;

5'-NUCLEOTIDASE; ADENOSINE TRIPHOSPHATE; ANIMALS; FEMALE; GUINEA PIGS; ILEUM; KINETICS; LIGANDS; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PLATELET AGGREGATION INHIBITORS; PYRIDOXAL PHOSPHATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; SURAMIN; VAS DEFERENS; XENOPUS LAEVIS;

EID: 0034601163     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(00)00135-1     Document Type: Article

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