Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 13, 2000, Pages 1447-1450

  Amori, Laura ^a   Costantino, Gabriele ^a   Marinozzi, Maura ^a   Pellicciari, Roberto ^a   Gasparini, Fabrizio ^b   Flor, Peter J ^b   Kuhn, Rainer ^b   Vranesic, Ivo ^b  

^a Unita di Riabilitazione Cognitiva   (Italy)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINO 2 CYCLOPENTENE 3 PHOSPHONO 1 CARBOXYLIC ACID; 1 AMINO 3 CYCLOPENTENE 3 PHOSPHONO 1 CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; GLUTAMATE RECEPTOR AGONIST; METABOTROPIC RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; RECEPTOR BINDING;

ANIMALS; BIOLOGICAL ASSAY; CHO CELLS; CRICETINAE; CYCLOPENTANES; EXCITATORY AMINO ACID AGONISTS; FORSKOLIN; HUMANS; MOLECULAR STRUCTURE; RECEPTORS, METABOTROPIC GLUTAMATE;

ANIMALIA;

EID: 0034601129     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00247-X     Document Type: Article

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