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Volumn 39, Issue 13, 2000, Pages 2290-2294

Total synthesis of bryostatin 3

Author keywords

Antitumor agents; Bryostatins; Macrolides; Natural products; Total synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; BRYOSTATIN; BRYOSTATIN 1; BRYOSTATIN 2; BRYOSTATIN 3; UNCLASSIFIED DRUG;

EID: 0034600771     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3773(20000703)39:13<2290::AID-ANIE2290>3.0.CO;2-6     Document Type: Article
Times cited : (156)

References (39)
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    • PhD thesis, Keio University
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    • Ohmori, K.1
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    • note
    • 1H NMR spectroscopy and the configuration of the resulting olefin was confirmed by ROESY experiments.
  • 39
    • 0343172866 scopus 로고    scopus 로고
    • note
    • The conformational difference between 21 and 22 had an influence on the stereoselectivity of methoxycarbonylmethylene introduction; the desired stereochemistry (Z:E = 8:1) was obtained by reagent C in the ease of 21, whereas 22 gave rise to no reaction under the same conditions. Additionally, reaction of 22 with A proceeded in favor of the undesired selectivity (Z:E = 1:4).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.